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Mutant Class Towers

by Aspect Of Death · 52 champions · 19 Sep 2026

SS Tier: Best for 40 CR 8
These champions have the highest chance to clear a fight in towers with a disadvantage of 40 challenge rating. 

Onslaught - Use heavy attack when opponent is not stunned to pause passives for an extended period and inflict daunted debuffs. Parry to build additional daunted debuffs up to a max of ten. Use sp1 after the first hit of a heavy attack to inflict neurochocks. Build to sp2 and throw after first hit of heavy attack to convert neuros to degeneration passives (relic comes in handy here). Build to over 1.5 bars of power and throw sp1 after heavy attack first hit, another sp1 will be able to be thrown immediately after. Magneto statcast relic preferred. Offensive stat focus special damage.

Jean Grey - Use light ending combos to inflict neuroshock debuffs. Once 12-15 are on the opponent, use sp1 to convert them to passives. Build to 1.5 bars of power, throw relic and use heavy attack throwing sp2 after the first hit of the heavy attacks. Quickly build up to a sp2 again before the passive neuroshocks expire. Time allows for one final sp2 to be thrown without passive neuroshocks by building to 1.5 bars agin relic into heavy and sp2 after first hit. Magneto statcast relic preferred. Offensive stat focus special damage.

Captain Britain - No need to build up psionic charges. Build to three bars of power, parry the opponent and immediately throw sp3. Then throw sp1 followed by building back to two bars of power and throwing sp2. Build back to two bars to throw a second sp2 after which spam sp1. Magneto statcast or gambit battlecast relic preferred. Offensive stat focus special damage or critical rating.

Archangel - Use heavy attacks to inflict bleed debuffs. Block attacks to inflict poisons. Use bleeds on a poisoned opponent to inflict neurotoxin passives. Parry heavy and throw sp2 when possible.  Mister Sinister battlecast relic preferred. Offensive stat focus critical rating.

Dani Moonstar - Every ten hits gain an illusion passive. Illusion passive makes opponents next hit into block trigger falter, gain barbed arrows when opponent misses and gain prowess when hitting faltered opponent. Throw sp1 at five prowess and when opponent is still faltered, sp1 will convert prowess to passives and o flick energy vulnerability. Throw sp2 twice, each time while having five barbed arrows and five prowess buffs. Magneto statcast or gambit battlecast relic preferred. Offensive stat focus special damage or critical rating.

Domino - Goal is to throw sp3 while domino is lucky. Parry opponent before using sp3 and atatck opponent right after. Use sp1 to refresh the bleed debuff from sp3. Magneto statcast relic preferred. Offensive stat focus special damage.

Cyclops - Sp3 is locked until 20 precision passives are gained. Precision passive will be gained every three hits. Additional precisions can be gained using intercepts. Throw sp2 when nearly at three bars of power to gain more precisions. After this, build back to three bars of power, this will be around the time 20 precisions are gained. Spam special attacks as soon as sp3 ends, power efficiency passive from sp3 makes this easy. Storm battlecast relic preferred. Offensive stat focus critical damage rating.

Deadpool X - Slap charges are built on first and third light attack. Build to basically three bars of power, throw sp2 after a light ending combo which disables sp3. While opponent is stunned dash in and quickly throw sp1 for shbleed burst. Quickly build slap charges to 10 and throw a second sp1 before daunted passive expires. With the time remaining build ten slap charges and sp1 for 40 bleed debuffs. Magneto statcast relic preferred. Offensive stat focus special damage.
Videos
S Tier: Very High Damage 11
These champions are some of the most solid in their class for towers. A 35 challenge rating disadvantage is nothing to them

Gentle - Throughout the fight, repeatedly punish the opponents heavy and special attacks to gain muscle mass, it is also possible to create opponents with gentles unstoppable passive to punish opponent. Throw sp2 three times. RNG will determine how quickly 12 muscle mass is built. Gambit battlecast relic preferred. Offensive stat focus special damage.

Bishop - Best against skill or energy damage opponents. Parry attacks to build prowess and throw sp2 as soon as possible. Three sp2 attacks can be thrown total. Gambit battlecast relic preferred. Offensive stat focus special damage.

Mister Sinister - Holding heavy while opponent is stunned will pause stun and gain vicious passive and genetic manipulation passive (this passive builds bleed debuffs on sinister). Throw sp1 when 9+ bleeds are on sinister, bleeds will be converted to degeneration debuffs on the opponents. Parry and hold heavy attack to pause degeneration debuffs. After knocking down opponent, hold heavy attack before stun expires to pause everything further. Rinse and repeat. Mister sinister battlecast relic preferred. Offensive stat focus special damage.

Shatterstar - Throughout the fight, repeatedly punish the opponents heavy and special attacks to inflict daunted debuffs. Uncanny passive allows sp3 to be thrown before three bars of power are gained. After sp3 throw sp2 as soon as possible. Then throw sp1 twice for bleed bursts. Magneto relic preferred. Offensive stat focus special damage.

Dust - Throughout the fight, repeatedly punish the opponents heavy and special attacks to inflict dust debuffs. Use light attacks to convert dust debuffs to passives, medium attacks inflict dust debuffs. By the time three bars of power are reached, roughly 70 passives will be on the opponent. Parry the opponent and quickly launch sp3, then while opponent is stunned dash in and throw sp2, this will inflict a passive stun and three physical vulnerability debuffs and use light attacks to convert to them to passives. Use a second sp2 and convert to a total of six physical vulnerability passives before spamming sp1 as many times as time will allow. Gambit battlecast relic preferred. Offensive stat focus special damage.

Pixie - The key to this fight is to gain as many soul wisps while building to nearly three bars of power before sp2 then spam sp1. Spells have cooldowns but should be activated as soon as possible. Hold heavy attack and pixie will evade when the opponent tries to strike, this will sleep the opponent, knockdown with heavy attack for additional soul wisp. In between spells, combo the opponent to reduce cooldown. Once at nearly three bars of power, evade once more and heavy attack launching sp2 after the first hit of the heavy attack, this will grant multiple potent prowess passives. From here launch sp1 as frequently as possible until time expires. Magneto statcast relic preferred. Offensive stat focus special damage.

Professor X - Use parry heavy to build charges while building to three bars of power. Once at 100 channeling charges, launch sp3. After sp3 you will want to spam special attacks. Holding block right after the special ends to cancel channeling and gain a prowess, hold heavy right before launching the next special attack to gain an additional prowess on activation. Gambit battlecast relic preferred. Offensive stat focus special damage.

North Star - Build to nearly three bars of power. Dash in and throw sp2 quickly to activate speed burst. Quickly launch sp1 to pause effects. Build to sp2 again and launch followed by sp1 as time nearly expires. Magneto statcast or gambit battlecast relic preferred. Offensive stat focus special damage.

Omega Red - Build to nearly three bars of power and launch sp2 to activate death field. Save relic until death field is going to expire. Quickly throw relic and build back to sp2 to launch again. One final sp2 can be thrown but the spores will not have the time to deal as much damage. (Optional: throw a heavy attack before death field ends after the second sp2 to prevent spores falling off. Mister sinister battlecast relic required. Offensive stat focus critical rating.

Iceman - Critical hits against the opponent have 70% chance to inflict frostbite passives, once these are nearly expired, throw a heavy attack to consume them for burst damage. Throw sp2 three times, each time while ice armor is active for additional attack rating. Gambit battlecast relic preferred. Offensive stat focus critical rating.

Cassandra Nova - link provided
Videos
A Tier: Solid for 35 3
These champions are hard hitters but need optimized gameplay, rotations, or masteries for a good win at 35 challenge rating disadvantage

Storm - Land two or three five hit combos before using heavy attack to pause prowess buffs. Throw sp2 once at two bars, dash in while opponent is stunned and land a heavy attack to further pause followed by a five hit combo. Repeat this for three sp2 total. Gambit relic preferred. Offensive stat focus special damage.


Kitty Pryde - Build to 1.5 bars of power, dash in to activate phase when above three prowess and activate sp1, bonus prowess is gained if the opponent misses while Kitty is dashing. After sp1 build prowess up to 20 max and power to two bars before dashing and launching sp2. Sp1 can be thrown again before a second sp2 but is also fine to skip and go straight to sp2. Gambit battlecast relic preferred. Offensive stat focus special damage. 

Cassandra Nova -

Storm X - Build to nearly two bars of power and punish opponents special attack with a heavy attack knockdown  after charging dormant prowess to 100, this is easiest against a champion will low reach in a special attack that is easy to gauge spacing like captain America or iron fist. Knocking down opponent will activate both tempests for additional damage. Throw sp2 when both tempests are active and at 6* prowess buffs. Three sp2 attacks can be thrown in this way. Gambit or storm battlecast relic preferred. Offensive stat focus special damage. 
B Tier: Decent Damage 4
These champions have either unorthodox playstyle or specific requirements to win at a 35 challenge rating disadvantage such as relics, crit RNG, or opponent AI

Apocalypse - Best if against a mutant opponent. Build to over 1.5 bars of power and throw sp1 after the first hit of a heavy attack. Use heavy attack to refresh debuffs on the opponent while building to two bars of power. Launch sp2 after the first hit if a heavy once again. Now use sp1 as many times as time will allow while using heavies to refresh. The first three special attacks will pause the timer but each after that will not and since the special animation is fairly lengthy, after sp1 sp2 sp1 sp1 time will run out in the middle of the sp1 of the sixth bar of power spent. Gambit battlecast relic preferred. Offensive stat focus special damage.

Wolverine X23 - Throughout the fight, intercept the opponent to gain Frenzy charges, dodging opponents special attack hits also gains frenzy. use medium ending combos only for the fight, throw sp2 twice during the fight with the first 40 seconds of the fight. With twenty seconds remaining, use a light ending combo to inflict eviscerating stun on the opponent. While this stun is active use light attacks only on the opponent until time is nearly expired and throw a final sp2 to kill the opponent. Wolverine battlecast relic preferred. Offensive stat focus critical rating.

Toad - Throw sp1 four times then throw sp2 when the opponent has between 7-9 paralytic poisons inflicted (use light ending combos to prevent applying them and use heavy attacks to consume them, this is how to control how many).
It is possible to, instead of using sp1 four times) push opponent to the wall and bait their special attack. Taking hit while close to the wall will gain paralytic secretions and the same potent prowess passives gained from throwing sp1. Magneto statcast relic or gambit relic preferred. Offensive stat focus special damage or critical rating.

Sunspot -
C Tier: Very Tight 35 4
These champions are the problem children and need a relatively smaller health pool opponent to have a chance at winning a 35 challenge rating disadvantage fight

Wolverine (Weapon X) - 

Emma Frost - 

Dazzler - 
D Tier: Near Impossible 2
These champions are the absolute worst in their class that can still technically pull through a 35 challenge rating disadvantage fight. They require either a fight like rocket raccoon or spider man stark enhanced and still need perfect AI to have a fighting chance

Colossus - One of the most difficult fights in all of towers. Focus must be to parry as often as possible and build armor up buffs. When at two bars of power, stun opponent and use a heavy attack, launching sp2 after the first hit. Build again to two bars of power while using well timed blocks against as many of the opponents special attack hits as possible. The second sp2 has to crit on the last hit or this fight is not possible. With the remaining time build to one bar of power, parry and heavy using sp1 after first hit. Gambit battlecast relic required (prends ma savate rune required). Offensive stat focus special damage.

Cable -
F Tier: Incapable 13
These champions are incapable of a win in a 35 challenge rating disadvantage fight. Nothing is saving them
7* Locked 7
These champions are not available at the seven star rarity...at least not yet

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