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ETERNAL ADVERSARIES

Captain America (WWII)
Red Skull
Captain America (WWII)Well-Timed Blocks generate a Fury Buff increasing Base Attack by 20% for 5 seconds.

Red SkullWell-Timed Blocks have +10% chance to Perfect Block for each Buff on Red Skull.

Unique Synergy: Does not stack with duplicate synergies

ESOTERIC INSIGHT

Iron Man (Infinity War)
Vision (Age of Ultron)
Vision
Iron Man (Infinity War)Molecular Armor is 15% more effective at reducing Power Drain, Power Steal, and Power Burn effectiveness.

Vision (Age of Ultron)Power Burn deals 20% more damage.

VisionPower Burn deals 20% more damage.

Unique Synergy: Does not stack with duplicate synergies.

ENTRÉE

Howard The Duck
Tigra
Vulture
Howard The DuckMax Indefinite Fury Buffs increased by +20.

TigraWhen fighting #Small Champions, Heavy Attacks have +50% increased Attack Rating.

VultureActivating Raptor Strike pauses Siphon Charges and Thermal Feedback Debuffs for 5 seconds.

Unique Synergy: Does not stack with duplicate Synergies.

ENHANCED WITH CARBONADIUM

Omega Red
Red Guardian
Omega RedWhen the fight begins, the Opponent is inflicted with up to 5 Death Spores.

Red Guardiantakes 50% less damage from incoming attacks while the Ablative Shield is at max Durability.

Unique Synergy: Does not stack with duplicate synergies.

ENHANCED SOLDIERS

Killmonger
Winter Soldier
Killmonger[15, 30]% chance to activate True Strike when intercepting the opponent’s Dash. 100% chance to activate True Strike when intercepting the opponent’s Dash.

Winter Soldier+[1, 2]% Attack for each hit of the Combo Meter to maximum of 100 hits. +5% Attack for each hit of the Combo Meter to maximum of 100 hits.

Unique Synergy: Does not stack with duplicate Synergies.

ENHANCED ILLUSIONIST

Mysterio
Spider-Man (Stealth-Suit)
MysterioReflection, Illusion and Frenzy Gas last for an additional 2 seconds.

Solo: Only affects this Champion and does not stack.

ENHANCED FORCEFIELD

Doctor Doom
M.O.D.O.K.
Red Skull
Doctor DoomGains +15% Perfect Block chance.

Solo: Only affects this Champion and does not stack.

ENHANCED ADAMANTIUM

M.O.D.O.K.
Old Man Logan
Wolverine (X 23)
M.O.D.O.K.+1000 Energy Resistance if Force Field is active.

Old Man Logan+10% Attack rating and attacks have a 20% chance to remove 1 Rock Stack or Rock Shield.

Wolverine (X 23)Enemy Bleed Debuffs suffer -25% Potency.

Unique Synergy: Does not stack with duplicate Synergies.

ENGULFED BY THE VOID

Void
Sentry
VoidWhen activating his Special 3, The Void gains a Reality Warp charge for 30 seconds, increasing the duration of any Fury effects activated afterward by 20 seconds.

Unique Synergy: Does not stack with duplicate synergies.

ENGINEERING EXPERTS

Black Panther (Civil War)
Black Panther
Hulkbuster
Mister Fantastic
Black Panther (Civil War)+40% Armor Up Ability Accuracy and Potency.

Black Panther+25% Bleed Debuff Duration.

HulkbusterEach Shock Debuff reduces the opponent’s Offensive Ability Accuracy during Special Attacks by 15%.

Mister Fantastic+1000 Physical Resistance.

Unique Synergy: Does not stack with duplicate Synergies.

ENGINEERING

Doctor Octopus
Vulture
Doctor OctopusResearch Categories no longer fall off over time.

VultureGain an additional +5 Chitauri Charge on Critical Hit.

Unique Synergy: Does not stack with duplicate synergies.

ENERGY CONDUIT - Cyclops

Bishop
Cyclops (Blue Team)
Cyclops (New Xavier School)
BishopStart the fight with +[1, 2] Prowess and +1 Bar of Power.

Cyclops (Blue Team)+[10, 15]% Energy Resistance.

Cyclops (New Xavier School)+[10, 15]% Energy Resistance.

ENERGY CONDUIT - Doctor Strange

Bishop
Doctor Strange
BishopStart the fight with +[1, 2] Prowess and +1 Bar of Power.

Doctor Strange+[10, 15]% Energy Resistance.

ENERGY CONDUIT - Electro

Bishop
Electro
BishopStart the fight with +[1, 2] Prowess and +1 Bar of Power.

Electro+[10, 15]% Energy Resistance.

ENERGY CONDUIT - Storm

Bishop
Storm
BishopStart the fight with +[1, 2] Prowess and +1 Bar of Power.

Storm+[10, 15]% Energy Resistance.

ENERGY ABSORPTION

Bishop
Havok
Mangog
Bishop+25% Regeneration Rate and +30% Prowess potency. Once per fight when struck by an energy attack inflict the Opponent with a Stun Debuff for 1.2 seconds.

Havok+5% Combat Power Rate and +20% Ability Power Rate. Once per fight when struck by an energy attack inflict the Opponent with a Stun Debuff for 1.2 seconds.

MangogOnce per fight when struck by an energy attack inflict the Opponent with a Stun Debuff for 1.2 seconds.

Unique Synergy: Does not stack with duplicate synergies.

ENEMY OF ALCHEMAX

Scorpion
Spider Man 2099
ScorpionIf Scorpion-Sense is active and Scorpion is Stunned, Scorpion’s Evade Ability Accuracy is increased to 100%.

Spider Man 2099When Striking the Opponent's Block, each Wither Debuff on the Opponent has 50% chance to inflict an additional Rupture.

Unique Synergy: Does not stack with duplicate synergies.

ENEMIES OF THE MYSTICAL REALM

Dormammu
Rintrah
Vision (Aarkus)
DormammuAfter Adding 1 Detonation Charge by Heavy Attack, Light attacks have a 30% chance to add 10 Detonation Charges.

RintrahStart the Fight with 5 Mystical Charges.

Vision (Aarkus)Increase Coldsnap Debuff damage by 50%.

Unique Synergy: Does not stack with duplicate synergies.

ENCROACHING INSANITY

Mysterio
Daredevil (Classic)
Daredevil (Hell's Kitchen)
MysterioPoison durations are increased by 2 seconds.

Solo: Only affects this Champion and does not stack.

ENCHANTED BLADES

Guillotine
Magik
Heimdall
GuillotineOnce per fight Heimdall will intercede on your behalf, dash back and hold Block for 1.5 seconds to gain an infinite Duration Precision Buff increasing Critical Rate by 250.

MagikOnce per fight Heimdall will intercede on your behalf, dash back and hold Block for 1.5 seconds to gain an infinite Duration Precision Buff increasing Critical Rate by 250.

Unique Synergy: Does not stack with duplicate synergies.