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A SPELL A DAY KEEPS THE DOCTOR AWAY

Black Widow (Claire Voyant)
Doctor Strange
Black Widow (Claire Voyant) : The final hit of Special 2 has a 50% chance to inflict Stun for 2 seconds.

Doctor Strange : The final hit of Special 2 has a 50% chance to inflict Stun for 2 seconds.

Unique Synergy: Does not stack with duplicate synergies.

A.I ENTHUSIASTS

Spider Man 2099
Iron Man
Scarlet Witch (Classic)
Spider Man (Stark Enhanced)
Spider Man 2099 : Second Medium attacks have a 25% chance to trigger Spider-Man 2099 Debuff Pausing ability.

Iron Man : Heavy Attack inflicts a Power Drain, removing 50% of the Opponent’s current power over 5 second(s). This effect has a 20 second(s) cooldown.

Scarlet Witch (Classic) : When granting a Buff on herself, gain 15% of a Bar of Power over 3 second(s).

Spider Man (Stark Enhanced) : On a Well Timed Block 33% chance to gain a Bulwark Passive, granting 700 Block Proficiency for 10 second(s).

Unique Synergy: Does not stack with duplicate synergies.

A.I. UPRISING

Nebula
Sentinel
Darkhawk
Warlock
Guillotine 2099

Nebula, Sentinel, Darkhawk, Warlock,Guillotine 2099 - gain 70% of a Bar of Power each time an immunity prevents a Bleed or Poison effect. This can't trigger more than once every 12 seconds.
Unique Synergy: Does not stack with duplicate synergies.

A.I.M. Alumni

Yelena Belova
M.O.D.O.K.
Sunspot
Hulkling
Wiccan

Synergy Champions: Gain +5% Attack Rating and +400 Critical Damage Rating. These bonuses are doubled while at Combo Meter 25+.
Unique Synergy: Does not stack with duplicate synergies.

A.I.M. TECHNOLOGY

Sunspot
M.O.D.O.K.
Red Hulk

Science Champions: Increase the Duration and Ability Accuracy of any Exhaustion, Fatigue, Heal Block, Petrify, Slow, and Weakness Debuffs by 10%. Increased to up to 40% based on Sunspot's Signature Level.
Unique Synergy: Does not stack with duplicate Synergies.

ABOMINABLE COMRADE

Abomination (Immortal)
Abomination

Abomination (Immortal), Abomination - Each time a Poison Debuff expires or is removed from the Opponent there is a 5% chance to inflict an Enervate Debuff for 3 seconds, preventing Power gained when struck.
Unique Synergy: Does not stack with duplicate synergies.

Abscission

King Groot (Deathless)
King Groot

Synergy Champions: While the Opponent is suffering from Incinerate or Poison, gain 15% Offensive Combat Power Rate.
Unique Synergy: Does not stack with duplicate synergies.

ABYSSAL HOSTS

Knull
Agent Venom
Anti-Venom
Carnage
Venompool
Knull : Gain an Unblockable Buff during his Special 1 and 2 Attacks.

Solo: Only affects this Champion and does not stack.

ADAMANTIUM ARROWS

Hawkeye
M.O.D.O.K.
Old Man Logan
Wolverine (X 23)
Wolverine (Weapon X)
Hawkeye : Arrow strikes remove all Rock Stacks & Rock Charges from the opponent.

Synergy Champions: +7% Attack Rating.
Unique Synergy: Does not stack with duplicate synergies.

ADVANCED IDEA MECHANICS

M.O.D.O.K.
Taskmaster
M.O.D.O.K. : Force Field recharges 1 second(s) faster.

Taskmaster : Deal 15% more Bleed damage.

Unique Synergy: Does not stack with duplicate synergies.

ADVANCED INTELLIGENCE

Nimrod
Ultron (Classic)
Ultron
Nimrod : Reduce Opponent Purify and Nullify Ability Accuracy by 50%.

Robots: 50% Chance to Inflict a Stun Debuff lasting 1.5 seconds when performing a Well-Timed block on a non-contact attack.
Unique Synergy: Does not stack with duplicate Synergies.

ADVANCED TECH

Wasp
Iron Man
Iron Man (Infinity War)
Wasp : When she intercepts the opponent’s Dash Attack and Petrify is not active on the opponent, inflict a Petrify of 100% Potency for 8 seconds. This can activate 3 times in a fight.

Iron Man, Iron Man(Infinity War) - Armor Up effects last for an additional 2 seconds.
Unique Synergy: Does not stack with duplicate Synergies.

AFTER HOURS

Joe Fixit
Moon Knight

Synergy Champions: Gain up to +30% Ability Accuracy and up to +600 Critical Damage Rating based on the current Moon Phase. Highest Potency at the New Moon.
Unique Synergy: Does not stack with duplicate synergies.

AGENTS OF ATLAS

Silk
Ms. Marvel (Kamala Khan)
Shang Chi

Synergy Champions: Gain +10 Critical Rating for each hit in the Combo Meter. Max hits: 100.
Unique Synergy: Does not stack with duplicate synergies.

AGENTS OF S.M.A.S.H.

Hulk (Ragnarok)
Hulk
Red Hulk
She-Hulk
Hulk (Ragnarok) : SMASH attacks gain +15% attack.

Hulk : Personal Fury Passives gain +20% potency.

Red Hulk : +2% attack for each Heat charge.

She-Hulk : Personal Fury Passives gain +20% potency.

Unique Synergy: Does not stack with duplicate synergies.

ALL ADAMANTIUM AND ATTITUDE

Jubilee
Wolverine
Jubilee : While Orange Fireworks are active, gain +15% Attack Rating.

Wolverine : +10% Critical Damage Rating.

Unique Synergy: Does not stack with duplicate synergies.

ALL RISE

Misty Knight
Daredevil (Classic)
Daredevil (Hell's Kitchen)
She-Hulk

Synergy Champions: Gain 5% Attack Rating.
Unique Synergy: Does not stack with duplicate synergies.

ALL-PURPOSE WEAPON OF WAR

Yellow Jacket
Yellow Jacket : Heavy Attack: 100% chance to spend 10 Core Charge to inflict a Slow Debuff for 10 seconds, preventing Evade or Unstoppable effects from activating. Opponents with a natural class advantage cannot be Slow.

Unique Synergy: Does not stack with duplicate Synergies.

ALPHA AND OMEGA

Omega Sentinel
Magneto (House of X)
Professor X
Omega Sentinel : Self Repair Buffs gain +35% potency.

Professor X, Magneto (House of X): Gain an additional Persistent Charge whenever an Opponent is defeated.
Unique Synergy: Does not stack with duplicate synergies.

ALPHA FLIGHT

Guardian
Sasquatch
Guardian : Well-Timed Blocks inflict a Shock Debuff, dealing 50% of Attack Rating as Energy Damage over 2 second(s).

Solo: Only affects this Champion and does not stack.