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ON GUARD FOR THEE

Guardian
Deadpool
Sabretooth
Squirrel Girl
Wolverine

All Champions except Guardian: The first 3 blocks have a 100% chance to be Perfect Blocks.
Unique Synergy: Does not stack with duplicate synergies.

OIL IS THICKER THAN BLOOD

Omega Sentinel
Sentinel
Omega SentinelIncinerate and Plasma Debuffs inflicted by Medium combo enders instantly Power Drain the Opponent for 5% of their Max Power.

SentinelKnocking down an Opponent removes 1 Prowess effect from them.

Unique Synergy: Does not stack with duplicate synergies.

OFF LIMITS

Hela
Hulk (Ragnarok)
HelaHela begins the fight with 1 Fury Buff, and if she is ever without a Fury Buff for 10 seconds, she gains one.

Hulk (Ragnarok)Hulk's chance to SMASH on Attacks increases by 400% while Face Me is active.

Unique Synergy: Does not stack with duplicate synergies.

OBSESSION

Kraven
Spider-Man (Classic)
Spider-Man (Symbiote)
KravenOnce per Fight when receiving damage that would result in a knockout, gain an Immortality Buff preventing death for 8 second(s).

Spider-Man (Classic)8+ Webbing: Root Debuff lasting 2 seconds.

Spider-Man (Symbiote)Armor Break Debuffs are paused during Specials and their duration is increased by 7 second(s).

Unique Synergy: Does not stack with duplicate synergies.

OATHSWORN

Odin
Heimdall
OdinOnce per fight Heimdall will intercede on Odin's behalf, dash back and hold Block for 1.5 seconds to gain a Perfect Block Buff, increasing Perfect Block chance by 100% for 10 second(s).

HeimdallHeimdall’s indefinite Fury, Armor Up, Precision and Aptitude Buffs gained from charging a Heavy Attack gain +15% potency.

Unique Synergy: Does not stack with duplicate synergies.

NOW YOU'RE PUNCHING WITH PORTALS

Spot
America Chavez
Wong
SpotPortal Blocks that block Basic Attacks grant Spot a non-stacking Fury Buff increasing Attack Rating by 20% for 6 seconds.

America ChavezLower Opponent Energy Resistance by 15% for each unique Parallel Dimension and Buff on the Opponent.

WongGain +20% Offensive Combat Power Rate while Wong has 3 active Spells or fewer.

Unique Synergy: Does not stack with duplicate synergies.

NOW YOU'RE PLAYING WITH POWER

The Champion
Titania
The ChampionContest’s Greatest Fighters now includes every Champion.

TitaniaIntercepting the Opponent pauses Titania’s Fury Passives for 2 seconds and reduces Haymakers' cooldown by 5 seconds.

Unique Synergy: Does not stack with duplicate synergies.

NOVA CORPS VETERANS

Air-Walker
Nova
Air-WalkerWhenever a Dark Tide Debuff is placed on the Opponent, 30% chance to place an additional one.

NovaReaching 75 Nova Charges refreshes Nova’s Fury Buffs, even while at maximum stacks.

Unique Synergy: Does not stack with duplicate synergies.

NOT THE HERO...

The Hood
M.O.D.O.K.
Mojo
Mole Man
Mysterio
The HoodKnocking the opponent down loads 3 Bullet(s).

Villain Champions: +3% Health & Attack Rating.
Unique Synergy: Does not stack with duplicate synergies.

NOT THE FACE!

Hit-Monkey
Deadpool
Deadpool (X-Force)
Hit-MonkeyIf any Bleed fails to apply to the Opponent due to an Immunity, Hit-Monkey deals a burst of instant Passive Bleed Damage for 50% of his Attack.

DeadpoolThe final hit of Special Attack 1 inflicts a Bleed Debuff (or Shbleed Dooboof), dealing 120% of Attack Rating as Direct Damage over 6 seconds.

Deadpool (X-Force)The final hit of Special Attack 1 inflicts a Bleed Debuff (or Shbleed Dooboof), dealing 120% of Attack Rating as Direct Damage over 6 seconds.

Unique Synergy: Does not stack with duplicate synergies.

NOT SO UNCANNY

Howard The Duck
Bishop
Gambit
Platinum Pool
Storm (Pyramid X)
Howard The DuckKnocking the opponent down removes all their Prowess effects and grants Howard 1 Prowess Buff for each effect removed this way, each increasing Special Attack Damage by 10% for 10 seconds.

Other Synergy Champions: +12% Prowess duration and Potency.
Unique Synergy: Does not stack with duplicate synergies.

NOT SO HIDDEN DRAGON

Dragon Man
Tigra
Dragon ManWhile the Opponent is Cornered, their Defensive Combat Power Rate is reduced by 25% when struck by Special Attacks.

TigraNeutralized Opponent’s have -100% Auto-Block Ability Accuracy.

Unique Synergy: Does not stack with duplicate Synergies.

NOT AFRAID OF DEATH

Hela
Thor (Ragnarok)
HelaStart each fight with 100 Spirit of the Dead Charges.

Thor (Ragnarok)Heal 10% of Max Health each time an opponent is knocked out.

Unique Synergy: Does not stack with duplicate synergies.

NO...NOT YOU…

Mysterio
Old Man Logan
MysterioWhen Regenerating from the use of Reflection Gas, Mysterio heals an additional 10% of the damage he took.

Old Man LoganThe first time Logan gains a 0 Damage Passive Bleed each fight, he gains 2 more. Additionally, his Regeneration Rate is increased by +10%.

Unique Synergy: Does not stack with duplicate Synergies.

NO SWORD LEFT BEHIND

Captain Britain
Rintrah
Taskmaster
Captain BritainEvery time a Debuff is purified, deal a burst of 25% Attack Rating as Energy Damage to Opponent.

RintrahIncrease Neutralize duration by 1 second(s).

TaskmasterIncrease the duration of Exploit Weakness Passive by 5 second(s).

Unique Synergy: Does not stack with duplicate synergies.

NO MORE PATIENTS

Sauron
Doctor Strange
Mister Sinister
SauronWhenever an Opponent heals, gain a 2% Regen Passive for 2 seconds. This goes on Cooldown for 5 seconds. Once this has been triggered 4 times, Inflict Heal Block Passive for 12 seconds.

Doctor StrangeWhenever an Opponent heals, gain a 2% Regen Passive for 2 seconds. This goes on Cooldown for 5 seconds. Once this has been triggered 4 times, Inflict Heal Block Passive for 12 seconds.

Mister SinisterWhenever an Opponent heals, gain a 2% Regen Passive for 2 seconds. This goes on Cooldown for 5 seconds. Once this has been triggered 4 times, Inflict Heal Block Passive for 12 seconds.

Unique Synergy: Does not stack with duplicate synergies.

NO MERCY

Sabretooth
Black Panther
Black Panther (Civil War)
Killmonger
SabretoothInflicting a Debuff reduces the opponent’s Ability Accuracy by 100% for 0.7 seconds.

Black Panther+30% Offensive Combat Power Rate when hitting opponents that are suffering from a Debuff.

Black Panther (Civil War)+30% Offensive Combat Power Rate when hitting opponents that are suffering from a Debuff.

Killmonger+30% Offensive Combat Power Rate when hitting opponents that are suffering from a Debuff.

Unique Synergy: Does not stack with duplicate synergies.

NO EVIL

Black Bolt
Daredevil (Hell's Kitchen)
Hawkeye
Hit-Monkey
Black BoltCritical Rating is increased by 300 for each Buff on Black Bolt.

Daredevil (Hell's Kitchen)+100% Perfect Block chance vs. Non-Contact Physical Attacks.

HawkeyeArrow strikes gain +20% Attack Rating against Bleeding opponents.

Hit-MonkeyThe last 3 Hits of each Heavy Attack are Guaranteed Critical Hits.

Unique Synergy: Does not stack with duplicate synergies.

NIGHT HAWKS

Darkhawk
Moon Knight
Night Thrasher
DarkhawkStart the fight in a random mode.

Moon KnightNew and Waxing Moons grant 30% of Max Power over 6 seconds at the beginning of the fight. Full and Waning Moons grant 10% of Max Health over 3 seconds at the beginning of the fight.

Night ThrasherEnemies have -12% Armor Rating for each unique debuff on them.

Unique Synergy: Does not stack with duplicate synergies.

NICK'S LEADERSHIP

Nick Fury

All Hero Champions except Nick: 10% Attack Rating. This boost is doubled if Nick is Dead.
Unique Synergy: Does not stack with duplicate synergies.