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MALICE

Invisible Woman
Psycho-Man
Invisible WomanWhile Invisible, Attacks have a 25% chance to place a Fragility Debuff on the Opponent.

Psycho-ManPsycho-Man’s Ability Accuracy reduction effects reduce Ability Accuracy by an additional -15% flat.

Unique Synergy: Does not stack with duplicate synergies.

MAGNIFICENT MANES

Red Guardian
Sabretooth
Red GuardianWhile the Ablative Shield is Fractured, gain an indefinite Passive Fury, granting +10% Attack Rating until the Shield is repaired.

SabretoothPotency of Fury effects are increased by 10%.

Unique Synergy: Does not stack with duplicate synergies.

MADCAP EXPERIMENTALISTS

Diablo
Doctor Octopus
Green Goblin
M.O.D.O.K.
DiabloSpecial Attacks have a 70% chance to inflict a Stun Debuff, lasting 1.5 second(s) per level of Special Attack used.

Doctor Octopus+35% Heal Block Debuff duration.

Green Goblin+1.5% Attack Rating per Cunning / Madness Charge.

M.O.D.O.K.+20% personal Debuff Duration.

Unique Synergy: Does not stack with duplicate synergies.

LULLABY

Black Widow
Hulk (Ragnarok)
Black WidowEvade chance increases by 100%.

Hulk (Ragnarok)When Struck Hulk has a 20% chance to ready a SMASH for his next attack.

Unique Synergy: Does not stack with duplicate synergies.

LOYAL MINISTER

Captain America
Captain America (WWII)
Captain America (Infinity War)
Punisher 2099
Captain AmericaClean hits gain +20% Attack rating if the opponent has a Stun, Bleed or Fatigue Debuff.

Captain America (WWII)Clean hits gain +20% Attack rating if the opponent has a Stun, Bleed or Fatigue Debuff.

Captain America (Infinity War)Clean hits gain +20% Attack rating if the opponent has a Stun, Bleed or Fatigue Debuff.

Punisher 2099Begin the fight with 25% additional Battery charge.

Unique Synergy: Does not stack with duplicate synergies.

Love Triangles:

Longshot
Rogue
LongshotLongshot's Special 2 has a 42% chance to inflict an additional Incinerate for each Bad Karma removed by Fate Seal.

RogueWhenever stealing a Buff Rogue deals 20% of her Base Attack as Degeneration damage for each Buff stolen.

All Female Champions: Gain 200 Critical Rating and 12% increased Ability Accuracy.
Unique Synergy: Does not stack with duplicate Synergies.

LOVE & THUNDER

Thor (Jane Foster)
Gorr
Korg
Thor (Ragnarok)
Valkyrie

Synergy Champions: +5% Combat Power Rate, +130 Armor Rating, +5% Perfect Block Chance & +6% Attack Rating.
Unique Synergy: Does not stack with duplicate synergies.

LOST DAUGHTERS OF ASGARD

Heimdall
Angela
Hela

All Champions except Heimdall: Once per fight Heimdall will intercede on your behalf, dash back and hold Block for 1.5 seconds to gain an infinite Duration Fury Buff increasing Attack by 15% of Base Attack.
Unique Synergy: Does not stack with duplicate synergies.

LORDS OF ENERGY

Black Bolt
Cyclops (New Xavier School)
Ikaris
Black BoltGains an Energize Buff granting +100% Combat Power Rate for 4 seconds, when a Personal Stun Debuff is applied.

Cyclops (New Xavier School)Gains +25% Fury when inflicting a Armor Break Debuff for 10 seconds. Max Stack of 4.

IkarisGains 1 bonus stacks of Incinerate on Special 1 when paired with Cyclops or Black Bolt (stacks if with both).

Unique Synergy: Does not stack with duplicate synergies.

LIVING STEEL CURTAIN

Colossus
Unstoppable Colossus
Red Guardian
ColossusActivating any Special Attack has a 50% chance to trigger a Unstoppable Buff, lingering 1.2 seconds after the Attack ends.

Unstoppable ColossusPersonal Fury Buffs gain an additional flat +10% chance to trigger and last 200% longer. Additionally landing a Heavy Attack pauses all personal Fury Buffs until another is gained.

Unique Synergy: Does not stack with duplicate synergies.

LIVE AND DIE BY THE SWORD

Guillotine
Nightcrawler
Ronin
GuillotineReaching a Combo Meter increment of 25 grants 1 Soul Charge.

NightcrawlerWhen switching Combat Modes, gain +350 Critical Damage Rating for 10 seconds.

RoninBlocking Attacks has a 50% chance to inflict a Bleed Debuff causing 25% of Attack Rating as direct damage over 5 seconds.

Unique Synergy: Does not stack with duplicate synergies.

LIVE AND DIE BY THE HORNS

Mangog
Purgatory
Rhino
Rintrah
MangogGain a 10% Attack Rating per Stagger on Opponent.

PurgatoryClass Souls last an extra 2 Fight(s).

RhinoGain a 25% Crit Rating when Unstoppable.

Rintrah30% chance to reapply any Ruptures removed on Special 2.

Unique Synergy: Does not stack with duplicate synergies.

LIKE OLD DAYS

Loki
Thor (Ragnarok)
LokiAscendant Signature Ability is enhanced to provide Power Gain while below 2 bars of Power.

Thor (Ragnarok)When struck for the first time each fight, 100% chance to gain a Combo Shield Passive lasting 10 seconds.

Unique Synergy: Does not stack with duplicate synergies.

LIGHTNING ROD

Storm
Toad
StormDeal 15% of Attack as a burst of instant Shock damage while the Opponent is suffering from a Stun Debuff.

ToadSpecial Attacks have +15% Crit Rating while Paralytic Secretion is active.

Unique Synergy: Does not stack with duplicate synergies.

LIEUTENANTS OF THE BLACK ORDER

Ebony Maw
Corvus Glaive
Cull Obsidian
Proxima Midnight

All Members of Thanos Army: When the fight starts, gain a True Damage Buff allowing Attacks to bypass Armor and Resistances for 30 seconds.
Unique Synergy: Does not stack with duplicate synergies.

LEGION ACCURSED

Diablo
Juggernaut
Kraven
Mephisto
DiabloPoison effects on the opponent reduce healing effects by 50% each instead of 30%.

JuggernautWhile Unstoppable, Juggernaut doubles his Armor Rating.

KravenTraps deal an additional +40% Direct Damage.

MephistoGain 50% of a bar of Power when a Poison Debuff would be gained. Cooldown: 10 seconds.

Unique Synergy: Does not stack with duplicate synergies.

LEGAL DEFENSE

She-Hulk
Daredevil (Classic)
Daredevil (Hell's Kitchen)
She-Hulk+15% duration for personal Fury Passive effects.

Daredevil (Classic)+800 Critical Rating during Special Attacks.

Daredevil (Hell's Kitchen)+800 Critical Rating during Special Attacks.

All Champions gain +15% Stun Ability Accuracy.
Unique Synergy: Does not stack with duplicate synergies.

LEECHING THY FRIEND

Havok
Sauron
HavokUpon consuming 1 Power Bar, gain an 20% Prowess Passive for 6 seconds.

SauronUpon gaining 1 Power Bar, gain a 20% Armor Up Passive for 6 seconds.

Unique Synergy: Does not stack with duplicate synergies.

LEADING AVENGERS

Sunspot
Captain America
Iron Man (Infinity War)
Iron Man

Avengers and New Avengers: When fighting Villain Champions, reduce the Potency of any Power Sting and damage over time effects by 10%. Increased to up to 40% based on Sunspot's Signature Level.
Unique Synergy: Does not stack with duplicate Synergies.

LAST HOPE

Captain Marvel
Ronin
Captain MarvelIntercepting attacks have +150 Critical Rating.

RoninThe duration of Bleed Debuffs is increased 3% for each active Cruelty.

Unique Synergy: Does not stack with duplicate synergies.