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MICROSCOPIC OBSERVATION

Ghost
Wasp
GhostSpecial Attacks are Unblockable when triggered while Phasing.

Unique Synergy: Does not stack with duplicate synergies.

METALIC AFFINITY

Cable
Magneto (House of X)
Taskmaster
Wolverine (X 23)
CableBegin the fight with 60% Poison Resistance.

Magneto (House of X)Gain an indefinite Prowess Buff, granting +20% Special attack damage.

TaskmasterExploit Weakness attacks deal +40% Damage.

Wolverine (X 23)Bleed & Cruelty effects gain 10% increased duration.

Unique Synergy: Does not stack with duplicate Synergies.

METAL MAYHEM

Colossus
Omega Red
Wolverine
Colossus+2% Attack Rating for each Armor Up Buff and Well Timed Blocks grant an Armor Buff.[Max 1 Stack]

Omega Red+4% Critical Damage for each Death Spore on the opponent.

Wolverine+20% Stronger Bleeds and +5% Critical Rating.

MERCS FOR MONEY

Domino
Masacre
DominoDebuffs last 1 second(s) longer.

MasacreAt the start of the fight, and when Ignited expires, gain between 1 and 5 Ignition Charges.

Unique Synergy: Does not stack with duplicate synergies.

MERCENARY COMPETITION

Crossbones
Hit-Monkey
Nebula
Platinum Pool
Yondu
Crossbones[Contempt] is expanded to include any Non-Villain Champion.

Mercenary & Villain Champions: +5% Attack Rating & +400 Critical Damage Rating.
Unique Synergy: Does not stack with duplicate synergies.

MERC WITH A MOUTH

Platinum Pool
Rogue
Platinum PoolPlatinumpool: Increase the chance to draw the Blood Drive Card.

Solo: Only affects this Champion and does not stack.

MENTAL IMMUNITY

Mysterio
Emma Frost
MysterioGrants immunity to reverse controls.

Emma FrostGrants immunity to reverse controls.

Unique Synergy: Does not stack with duplicate synergies.

MEMORIES OF GENOSHA

Emma Frost
Sentinel
Emma Frost+15% Attack Rating in Diamond Form.

Sentinel+4 Physical Resistance for each Analysis Charge.

Unique Synergy: Does not stack with duplicate synergies.

ME AND THESE IDIOTS ARE GONNA OBLITERATE YOU!

Rocket Raccoon
Dragon Man
Gamora
Groot
Star-Lord

#Guardian Champions: Gain +7% Attack Rating.

MAYBE LATER

Agent Venom
Anti-Venom
Agent VenomGain 10% Power anytime a Debuff is purified.

Anti-VenomInflicting a Genetic Memory Debuff deals a burst of 40% of Modified Attack in Physical Damage.

Unique Synergy: Does not stack with duplicate synergies.

MAYBE AVENGER

Captain America (Infinity War)
Iron Man (Infinity War)
QuickSilver
Thor (Ragnarok)
Captain America (Infinity War)Increase the potency of Fury effects by 25%.

Iron Man (Infinity War)While the Opponent is suffering from Armor Break, they are also inflicted with a Passive Cowardice, reducing Special Damage by 40%.

QuickSilverIncrease Block Proficiency by [1000, 1250].

Thor (Ragnarok)75% chance to Purify any non-Damaging Debuff.

Unique Synergy: Does not stack with duplicate synergies.

MAXIMUM OUTPUT

Bishop
Havok
Nova
BishopReceiving Energy Damage generates 1 additional stack of Prowess.

Havok10% chance to place a new Plasma Build Up Debuff on the Opponent when it is Removed or Purified.

NovaGain 1 Nova Charge each time Nova receives Energy Damage.

Unique Synergy: Does not stack with duplicate synergies.

MASTERS OF THE SWORD

Guillotine
Morningstar
GuillotineTemporary Soul Charges last 10 seconds longer.

MorningstarAt the start of the fight, if she has less than 2 Captured Souls, she gains 1.

Unique Synergy: Does not stack with duplicate synergies.

MASTERMINDS

Mister Sinister
M.O.D.O.K.
Kingpin
Ultron
Mister SinisterEach time the opponent uses a Special Attack they become Power Locked for 6 seconds.

M.O.D.O.K.Each time the opponent uses a Special Attack they become Power Locked for 6 seconds.

KingpinEach time the opponent uses a Special Attack they become Power Locked for 6 seconds.

UltronEach time the opponent uses a Special Attack they become Power Locked for 6 seconds.

Unique Synergy: Does not stack with duplicate synergies.

MASTERMINDS

Loki
Magneto
Magneto (House of X)

All Champions gain +[17, 20]% Energy Damage once a Combo of 15 or more hits is reached.

MASTERLESS

Moon Knight
Ronin
Moon Knight30% chance to instantly Regenerate 35% of damage taken when struck.

RoninGain a Fury Buff increasing Attack Rating by 15% for 4 seconds upon switching Stances.

Unique Synergy: Does not stack with duplicate synergies.

MASTERFUL COMBAT

Black Panther
Hercules
Black PantherDashing back during a Basic Attack combo inflicts a non-stacking Infuriate Debuff for 5 seconds, making the Opponent more aggressive and reducing their Offensive Ability Accuracy by 30%. Cooldown 10 seconds.

HerculesOn activation of Special Attack 1 or 2, gain an Unblockable Buff for 3 seconds.

Unique Synergy: Does not stack with duplicate synergies.

MASTER MARTIAL ARTISTS

Shang Chi
Iron Fist
Iron Fist (Immortal)
Shang ChiStart the fight with 4 Chi Charge(s).

Iron FistEach hit in all Special Attacks are Guaranteed Critical Hits and gain a flat +35% personal Armor Break Ability Accuracy.

Iron Fist (Immortal)Each hit in all Special Attacks are Guaranteed Critical Hits and gain a flat +35% personal Armor Break Ability Accuracy.

Unique Synergy: Does not stack with duplicate synergies.

MARVELOUS

Captain Marvel (Classic)
Ms. Marvel
Captain Marvel
Captain Marvel (Classic)While Fury is active, Beam Attacks are Unblockable.

Ms. MarvelWhile Fury is active, Beam Attacks are Unblockable.

Captain MarvelBlocking energy-based attacks grants 2% of Max Power.

Unique Synergy: Does not stack with duplicate synergies.

MANY AS ONE

Hulk (Immortal)
Purgatory
Hulk (Immortal)Triggering Immortality consumes 5% less Max Health as Gamma Radiation.

Purgatory20% chance per Captured Class Soul to instantly Regenerate 20% Health just before being Knocked Out, once per fight.

Unique Synergy: Does not stack with duplicate synergies.