Every time a Debuff is purified, deal a burst of 25% Attack Rating as Energy Damage to Opponent.

Increase Neutralize duration by 1 second(s).

Increase the duration of Exploit Weakness Passive by 5 second(s).

Unique Synergy: Does not stack with duplicate synergies.

Whenever an Opponent heals, gain a 2% Regen Passive for 2 seconds. This goes on Cooldown for 5 seconds. Once this has been triggered 4 times, Inflict Heal Block Passive for 12 seconds.

Whenever an Opponent heals, gain a 2% Regen Passive for 2 seconds. This goes on Cooldown for 5 seconds. Once this has been triggered 4 times, Inflict Heal Block Passive for 12 seconds.

Whenever an Opponent heals, gain a 2% Regen Passive for 2 seconds. This goes on Cooldown for 5 seconds. Once this has been triggered 4 times, Inflict Heal Block Passive for 12 seconds.

Unique Synergy: Does not stack with duplicate synergies.

Inflicting a Debuff reduces the opponent’s Ability Accuracy by 100% for 0.7 seconds.

+30% Offensive Combat Power Rate when hitting opponents that are suffering from a Debuff.

+30% Offensive Combat Power Rate when hitting opponents that are suffering from a Debuff.

+30% Offensive Combat Power Rate when hitting opponents that are suffering from a Debuff.

Unique Synergy: Does not stack with duplicate synergies.

Critical Rating is increased by 300 for each Buff on Black Bolt.

+100% Perfect Block chance vs. Non-Contact Physical Attacks.

Arrow strikes gain +20% Attack Rating against Bleeding opponents.

The last 3 Hits of each Heavy Attack are Guaranteed Critical Hits.

Unique Synergy: Does not stack with duplicate synergies.

Start the fight in a random mode.

New and Waxing Moons grant 30% of Max Power over 6 seconds at the beginning of the fight. Full and Waning Moons grant 10% of Max Health over 3 seconds at the beginning of the fight.

Enemies have -12% Armor Rating for each unique debuff on them.

Unique Synergy: Does not stack with duplicate synergies.

All Hero Champions except Nick: 10% Attack Rating. This boost is doubled if Nick is Dead.
Unique Synergy: Does not stack with duplicate synergies.

#Hero Champions: While Hercules is alive gain +[10, 15]% Attack Rating while under the effects of Poison from the Liquid Courage Mastery.
Unique Synergy: Does not stack with duplicate synergies.

Power Gain and Power Leech Effects gain 25% increased duration.

If the Opponent has 1 or more Buffs active, Special Attack 1 becomes Unblockable.

Spell Pause duration increases by 2 second(s).

Spell durations are increased by 20%.

Unique Synergy: Does not stack with duplicate synergies.

Opponent suffers -65% Evade Ability Accuracy.

Other Synergy Champions: Up to +15% Attack Rating, based on missing health.
Unique Synergy: Does not stack with duplicate synergies.

Starts the fight with a Permanent Armor Up Buff increasing Armor Rating by 45%.

The Shock Baton Gadget Debuff passively reduces Defensive Combat Power Rate by 30%.

Heavy Attacks have a 50% chance to refresh Nova Surge Buffs.

Unique Synergy: Does not stack with duplicate synergies.

If a personal Shock effect is prevented by Immunity. Nimrod inflicts matching Incinerate Debuffs instead. Incinerate reduces Block Proficiency by 50% and prevents the activation of Perfect Block.

Robots: +5% Combat Power Rate for each Shock on the Opponent. Max 50%.
Unique Synergy: Does not stack with duplicate Synergies.

Mutant Champions: Ability Accuracy is increased by 30% during Special Attacks. Increased to up to 60% based on Sunspot's Signature level.
Unique Synergy: Does not stack with duplicate Synergies.

Inflict Rupture and Critical Rupture instead of Bleed and Critical Bleed when fighting Bleed Immune Champions.

#New Avengers: Gain [400, 420, 450] Critical Rating.
Unique Synergy: Does not stack with duplicate synergies.

Arrow strikes Pause all Slow Debuffs on the opponent for 6 seconds per level of Special Attack.

Other Synergy Champions: +7% Attack Rating.
Unique Synergy: Does not stack with duplicate synergies.

Successful Nullifies deal a burst of energy damage equal to 20% of Doom's Attack.

Solo: Only affects this Champion and does not stack.

Reduce the duration of the target’s Power Lock effects by 50% and generate 50% Power each time a Power Lock expires when facing a target of the Mystic Class.

Unique Synergy: Does not stack with duplicate synergies.

Deal 50% of Base Attack as Direct Damage when Nullifying a Buff off the Opponent.

Mordo places a Detonate Buff on the opponent at the start of the fight which lasts 20 seconds and deals 50% of Mordo’s Base Attack as a burst of Energy Damage when it’s Nullified or Expires.

Begin the fight with 1 bar of Power.

Unique Synergy: Does not stack with duplicate synergies.

Mystic Champions deal 30% of their Attack as Direct Damage to their Opponent when Nullifying one of their Buffs.
Unique Synergy: Does not stack with duplicate synergies.

Special Attack 2 can convert up to 3 of any Buff, instead of only converting Loas.

All effects that Power Drain the Opponent also deal a burst of Energy Damage for 15% of Dormammu’s attack.

Mystic opponents suffer -15% Buff potency.

The Nullification Aura is paused during any Special Attack.

Unique Synergy: Does not stack with duplicate synergies.

When neutralizing the Opponent Wiccan also inflicts a Tracking Debuff, bypassing the effects of Miss for the duration of the Neutralize.

Solo Synergy: Only affects this Champion and does not stack.