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Mano A Mano

White Tiger
Gladiator
White TigerPower Steal has a 49.5% chance of not going on cooldown.

GladiatorCharging a Heavy Attack while the Opponent’s back is against the wall grants a Fury Buff increasing Attack Rating by +50.5% for 2 seconds, paused during Gladiator’s Special Attacks. Max stacks: 3.

Unique Synergy: Does not stack with duplicate synergies.

Avatars

White Tiger
Ghost Rider
Juggernaut
Moon Knight
Silk

Synergy Champions: At the start of each fight, rapidly gain 50% of a Bar of Power. If a Relic is equipped, also gain 20% Spirit Gauge.
Unique Synergy: Does not stack with duplicate synergies.

Amulets Of Power

White Tiger
Darkhawk
Elsa Bloodstone
White Tiger+20% Special Damage.

DarkhawkHolding Block grants a Fury Passive every 0.2 seconds, each increasing Attack Rating by +10% for 2 seconds.

Elsa BloodstoneAfter Purifying a Debuff, gain a non-stacking Cruelty Buff increasing Critical Damage Rating by +600 for 9 seconds.

Unique Synergy: Does not stack with duplicate synergies.

Contrast Cast

White Tiger
Black Panther
Mister Negative
White TigerGain 15% personal Buff duration.

Black PantherGain 15% personal Debuff duration.

Mister NegativeGain 15% personal Buff and Debuff duration.

Unique Synergy: Does not stack with duplicate synergies.

Avengers Academy

White Tiger
Hawkeye
QuickSilver
Tigra
Wolverine (X 23)

Synergy Champions: Gain +100 Critical Rating for each unique Synergy Champion on the team. If all Synergy Champions are present, also gain +300 Critical Damage Rating.
Unique Synergy: Does not stack with duplicate synergies.

Ultimate Teammates

White Tiger
Iron Fist
Luke Cage
Nova
Spider-Man (Classic)

Synergy Champions: Gain +4% Perfect Block Chance for each unique Synergy Champion on the team. If all Synergy Champions are present, also gain +30% Attack Rating.
Unique Synergy: Does not stack with duplicate synergies.

Pitcher Perfect

Bullseye
Cyclops (New Xavier School)
Cyclops (Blue Team)
BullseyeIf an attack doesn’t Critically Hit a non-Mutant Opponent, gain a non-stacking 50% Fury Buff for 3 seconds. This Buff will not re-trigger while already active, and is not affected by Ability Accuracy reduction.

Cyclops (New Xavier School)Intercepting the Opponent with a Beam Attack grants a non-stacking 50% Fury Buff for 3 seconds.

Cyclops (Blue Team)Intercepting the Opponent with a Beam Attack grants a non-stacking 50% Fury Buff for 3 seconds.

Unique Synergy: Does not stack with duplicate synergies.

Did We Just Become Best Friends

Bullseye
Deadpool
Deadpool (X-Force)
BullseyeBlock Penetration increases by 5% for each personal Cruelty Passive.

DeadpoolStart each fight with an indefinite Meat Armor Buff granting 20% Armor Rating and 10% Block Proficiency. This Buff is removed if Deadpool is struck by a projectile, or inflicted with Bleed.

Deadpool (X-Force)Start each fight with an indefinite Meat Armor Buff granting 20% Armor Rating and 10% Block Proficiency. This Buff is removed if Deadpool is struck by a projectile, or inflicted with Bleed.

Unique Synergy: Does not stack with duplicate synergies.

Black and White and Red all over

Bullseye
Daredevil (Classic)
Daredevil (Hell's Kitchen)
Elektra
BullseyeIf Daredevil or Daredevil (Hell’s Kitchen) are Knocked Out, start each fight with an indefinite 10% Cruelty Buff.

Daredevil (Classic)If Elektra is Knocked Out, start each fight with an indefinite 20% Fury Buff.

Daredevil (Hell's Kitchen)If Elektra is Knocked Out, start each fight with an indefinite 20% Fury Buff.

ElektraIf Bullseye is Knocked Out, start each fight with an indefinite 20% Precision Buff.

Unique Synergy: Does not stack with duplicate synergies.

Eye for an Eye

Bullseye
Hawkeye
Kate Bishop

Synergy Champions: Dialed In Passives increase the duration of their associated effects by an additional +3%.
Unique Synergy: Does not stack with duplicate synergies.

TWO SIDES OF THE COIN

Guillotine (Deathless)
Guillotine
Guillotine (Deathless)Souls last 30% longer and are paused during either Champion's Special Attacks.

GuillotineThe potency of healing from damage taken by the Opponent is increased by 66.6%.

Unique Synergy: Does not stack with duplicate synergies.

Deadless Enemies

Guillotine (Deathless)
Guillotine 2099
Guillotine
Morningstar
Purgatory

Synergy Champions: For each Synergy Champion present, gain 40 Critical Rating and 2% Ability Power Rate.
Unique Synergy: Does not stack with duplicate synergies.

Mutant Absorption

Onslaught
Professor X
Magneto
Magneto (House of X)
OnslaughtWhen defeating a Mutant Champion, Onslaught Passively Regenerates 15% of his missing Health.

Solo Synergy: Only affects this Champion and does not stack.

Close Enough

Onslaught
Cable
Stryfe
OnslaughtStriking an Opponent or their Block while they are Unstoppable consumes 3 personal Daunted effects and removes the Unstoppable. Cooldown: 20 seconds.

Solo Synergy: Only affects this Champion and does not stack.

Red Onslaught

Onslaught
Red Skull
OnslaughtAgainst Skill Champions, while attacking, Onslaught Passively Regenerates 85% of incoming Physical Damage.

Solo Synergy: Only affects this Champion and does not stack.

Final Boss

Onslaught
Apocalypse
OnslaughtWhen Onslaught’s Combo Meter passes a multiple of 20, gain a non-stacking Crush Charge.

Solo Synergy: Only affects this Champion and does not stack.

Takeover

Onslaught
Sentinel
OnslaughtGain +1075 Block Proficiency.

Solo Synergy: Only affects this Champion and does not stack.

Past and Future Self

Maestro
The Overseer
MaestroGain Neutronium 20% faster. During Superior Rage, Neutronium expires 20% slower.

The OverseerPersonal Special Concussion Debuffs gain +10% flat potency but their stack limit is reduced to 4.

Unique Synergy: Does not stack with duplicate synergies.

Big Bads

Maestro
Red Skull
Kang the Conqueror
Thanos

Synergy Champions: Gain +100 Armor Rating, +100 Critical Rating, +100 Critical Damage Rating, and +3% Perfect Block Chance, doubled when fighting the final node in a Quest.
Unique Synergy: Does not stack with duplicate synergies.

By your Powers Combined

Maestro
Captain America
Hulk
Iron Man
Ronan
MaestroGain +10% Fury potency for each other Synergy Champion on the team.

Solo Synergy: Only affects this Champion and does not stack.