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What You Fear, You’ll Destroy

Chee'ilth
Abomination
Abomination (Immortal)
Red Hulk
The Overseer
Chee'ilthWhen struck while performing a Heavy Attack, become Passively Unstoppable for 3 seconds. Cooldown: 45 seconds. [Gamma]: Cooldown becomes 5 seconds.

Synergy Champions: Personal damaging effects gain 15% increased potency.
Unique Synergy: Does not stack with duplicate synergies.

What You Don’t Know, You’ll Fear

Chee'ilth
Absorbing Man
Hulk (Ragnarok)
Joe Fixit
Rhino
Chee'ilthWhen Blocking a Heavy Attack, become Passively Unstoppable for 3 seconds. Cooldown: 45 seconds. [Gamma]: Cooldown becomes 5 seconds.

Synergy Champions: +8% Attack Rating.
Unique Synergy: Does not stack with duplicate synergies.

If You Don’t Talk, You Won’t Know Them

Chee'ilth
Hulk
Hulk (Immortal)
Sasquatch
She-Hulk
Chee'ilthSister Eagle grants 3 additional Cleanse Passives at the start of each fight. [Gamma]: Gain 8 Cleanse Passives instead.

Synergy Champions: +8% Health.
Unique Synergy: Does not stack with duplicate synergies.

First on the Scene

Chee'ilth

All Champions except Chee’ilth: Regeneration Buffs and Passives gain 5% increased potency.
Unique Synergy: Does not stack with duplicate synergies.

First

Kushala
Dani Moonstar
Chee'ilth
KushalaBlessings of Power reduce the Opponent’s Ability Power Rate by an additional -10% each.

Dani MoonstarThe first time each fight Dani would be struck, she gains a Combo Shield Passive for 5 seconds.

Chee'ilthChee’ilth has a 100% chance to block Unblockable Special Attacks while she has 8 or more personal Cleanse Passives.

Unique Synergy: Does not stack with duplicate synergies.

Fire Cleanses

Kushala
Longshot
Masacre
Phoenix
Sunspot
Kushalaor each Damaging effect on the Opponent, Heavy Attacks deal extra damage equal to 5% of Kushala’s base attack.

Synergy champions except Kushala: Incinerate effects are 15% more potent.
Unique Synergy: Does not stack with duplicate synergies.

Shadows on the Road Ahead

Kushala
Doctor Strange
Sorcerer Supreme
Wong
Doctor Voodoo

Synergy Champions: Activating a Special Attack 3 grants a non-stacking 10% Amplify Passive for 15 seconds.
Unique Synergy: Does not stack with duplicate synergies.

Shadows on the Road Behind

Kushala
Ghost Rider
Cosmic Ghost Rider

Synergy Champions: Damaging Effects gain 10% increased potency.
Unique Synergy: Does not stack with duplicate synergies.

It’s Alive!

Morbius
Punisher
Mole Man
PunisherWhile Indestructible, hits grant a Regeneration Passive, recovering 2% of Missing Health over 3 seconds. Max 3 stacks.

Synergy Members: +10% Bleed Debuff duration.
Unique Synergy: Does not stack with duplicate synergies.

The Hunter and the Hunted

Morbius
Blade
MorbiusWell-Timed Blocks inflict a Bleed Debuff, dealing 1% of Attack Damage over 10 seconds. Max 10 stacks.

BladeDamaging Debuffs on the Opponent lower Ability Power Rate by 5%. Max 10 Debuffs.

Unique Synergy: Does not stack with duplicate synergies.

Tormented Souls

Morbius
Werewolf By Night
Elsa Bloodstone
Man-Thing
Ghost Rider
Punisher
MorbiusAt the start of each fight, inflict a 35% Torment Passive for 30 seconds.

Werewolf By NightAt the start of each fight, inflict a 35% Torment Passive for 30 seconds.

Elsa BloodstoneAt the start of each fight, inflict a 35% Torment Passive for 30 seconds.

Man-ThingAt the start of each fight, inflict a 35% Torment Passive for 30 seconds.

Ghost RiderAt the start of each fight, inflict a 35% Torment Passive for 30 seconds.

#Legion of Monsters Champions: At the start of each fight, inflict a 35% Torment Passive for 30 seconds.
Unique Synergy: Does not stack with duplicate synergies.

Lethal Protectors

Morbius
Carnage
Venom
Misty Knight
Iron Fist

All Champions gain +85 Critical Rating.
Unique Synergy: Does not stack with duplicate synergies.

Big Game Monsters

Werewolf By Night
Man-Thing
Werewolf By NightChilling Howl inflicts a 5% Physical Vulnerability Debuff for 25 seconds. Max stacks: 3.

Solo Synergy: Only affects this Champion and does not stack.

Beast Friends

Werewolf By Night
Sasquatch
Tigra
Beast
Sabretooth

Synergy Champions: Gain +350 Physical Resistance.
Unique Synergy: Does not stack with duplicate synergies.

Pure Instinct

Werewolf By Night
Moon Knight
Werewolf By NightDashing forward from outside of striking distance grants a 2% Fury Passive per Buff on the Opponent for 1.2 seconds. This Fury is paused during Basic and Special Attacks. Max stacks: 10.

Solo Synergy: Only affects this Champion and does not stack.

United By Chance

Werewolf By Night
Morbius
Ghost Rider
Elsa Bloodstone
Man-Thing
Punisher
Werewolf By NightStart each fight with a 10% Vicious Passive for 30 seconds.

MorbiusStart each fight with a 10% Vicious Passive for 30 seconds.

Ghost RiderStart each fight with a 10% Vicious Passive for 30 seconds.

Elsa BloodstoneStart each fight with a 10% Vicious Passive for 30 seconds.

Man-ThingStart each fight with a 10% Vicious Passive for 30 seconds.

PunisherGain this synergy’s bonus after taking a Lethal Blow during the Quest.

Legion of Monsters Champions (Morbius, Ghost Rider, Elsa Bloodstone, Man-Thing): Start each fight with a 10% Vicious Passive for 30 seconds.
Unique Synergy: Does not stack with duplicate synergies.

Great Guys

Gladiator
Hyperion
Sentry
Ikaris

Synergy Champions: While far from the Opponent, gain an indefinite Unstoppable Buff. This Buff will not trigger while being struck by the Opponent, and is removed if either Champion re-enters striking distance.
Unique Synergy: Does not stack with duplicate synergies.

Flarking Annihilators

Gladiator
Ronan
Silver Surfer
Nova

Synergy Champions: When gaining a Bar of Power, gain a non-stacking 5% Fury Buff for 10 seconds. Each other living Synergy Champion increases this potency by +5% flat.
Unique Synergy: Does not stack with duplicate synergies.

Punk’s Pizzazz

Gladiator
Sorcerer Supreme
Hulk (Ragnarok)

Synergy Champions: Heavy Attacks are Passively Unblockable if Gladiator is alive, and they gain +10% Attack Rating if Sorcerer Supreme is alive, +750 Critical Rating if Hulk (Ragnarok) is alive.
Unique Synergy: Does not stack with duplicate synergies.

Praetor Of The Imperial Guard

Gladiator

All Champions except Gladiator: Gain 5% Attack Rating and 5% Armor Rating.
Unique Synergy: Does not stack with duplicate synergies.