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Mystic Class Towers

by Aspect Of Death · 54 champions · 19 Sep 2026

SS Tier: Best for 40 CR 4
These champions have the highest chance to clear a fight in towers with a disadvantage of 40 challenge rating. 

Madelyne Pryor - Activate GOBLIN INSTIGATORS prefight. Build to sp2 and launch while opponent is against the wall. Bait opponents heavy and special attacks and punish for insane scaling degeneration passives, this also triggers when punishing the opponent throwing five consecutives hits into block. Throw sp2 to that when the attack ends pit duration has already expired. Repeat punishments for degenerations until the opponent inevitably falls. Ghost rider battlecast preferred. Offensive stat focus special damage or critical rating.

Symbiote Supreme - Against an opponent with buffs to remove with nullify or stagger, use combos until Chthons Cunning passive expires and massive power is agined to throw sp3 as soon as possible. Afterwards cycle through using sp2 attacks against the opponent and sp3 when genetic blessings are close to expiry. Buffs from the opponent fuel this fight. Scarlet witch battlecast relic preferred. Offensive stat focus special damage.

Kushala - Total flow of fight is sp2 sp1 sp2 sp1 each at three stacks of all three Blessings. Parry the opponent for Blessing of wisdom and use a heavy attack for Blessing Justice followed by an intercept for Blessing of Power, gaining the third will pause spells. Repeat this to get two of every Blessing. Bait the opponents sp1 then get an additional stack of each Blessing before building to and throwing sp2 while all 9 total Blessings are active for highest potency soul barb. Build up to 10 ignition buffs on the opponent before using sp1. Maintain blessings through the fight by gaining them back as they expire. Iron fist relic preferred.
(sp3 rotation) Build all 9 Blessings and throw relic before launching sp3. After using sp3, quickly build to sp2 followed by sp1. Ghost rider relic preferred.
For both, offensive stat focus special damage.

Sorcerer Supreme - Activate Raggadorrs Resolve (armor passive) prefight. Use a five hit combo then parry the opponent and use a heavy attack. Combo the opponent until nearly at three bars of power and throw sp2 while Cyttoraks Ferocity (fury passive) is active. Quickly use relic and heavy attack on the opponent then combo into sp2, more power will be gained to enable a quick third sp2. Two more sp2 attacks can be thrown before time expires. Scarlet Witch battlecast relic mandatory. Offensive stat focus critical rating.
Videos
S Tier: Very High Damage 8
These champions are some of the most solid in their class for towers. A 35 challenge rating disadvantage is nothing to them

Spiderman (Pavitr Prabhakar) - Parry and use a heavy attack to power steal. As the opponent gets up, rush in and combo into sp1 to make them cross the mystic web in the corner during the special attack for additional spider seal buffs. Continually have the opponent cross over the mystic web as it activates, use another sp1 knocking them into the corner. Once the opponent has at least 15 spider seal buffs, use sp2 when the opponent is not in the corner so the sp2 knocks them into the corner for large burst. Quickly build to sp2 once more with the remaining time and launch while the opponent crosses mystic web. Iron fiat battlecast relic preferred. Offensive stat focus special damage.

Shathra - Flow of fight is sp1 sp1 sp2 sp1 sp2. By holding heavy attack consumes astral wasps to gain power. Combo the opponent until sp1 and launch, parry the opponent after and charges heavy, releasing when the stun is about to expire and launch sp1 after first hit of heavy. Then create space between yourself and opponent and hold heavy before releasing and activating sp2 after first hit. Do the same for another sp1 and sp2 to follow. When timing is right one more sp2 can be charged and thrown before time expires. Scarlet witch battlecast relic preferred. Offensive stat focus special damage.

Werewolf by Night - Begin the fight with a medium attack to inflict ruptures, then quickly swipe back and idle to howl and recieve a power gain passive. Combo the opponent and build up to sp2. When able to howl again, do so and launch sp2 into opponent. Sp2 three times is possible for max damage. Only trigger the howl while the opponent is inflicted with rupture debuffs. Scarlet witch battlecast relic preferred. Offensive stat cast special damage.

Absorbing man - 

Tigra - 

Juggernaut - Against opponents that do not inflict debuffs, build unstoppable charges by comboing the opponent and build to two bars of power and launch when at 10 unstoppable buffs. Throw three sp2 attacks total, an additional sp2 can be thrown if opponent has enough buffs to feed mystic dispersion. Juggernaut battlecast relic preferred.

Agatha Harkness - 

Doctor Strange - Only one or two points in the recoil mastery at most. Willpower mastery must be active and five points in mystic dispersion. Use a heavy attack in the middle of a combo and hol until Hoggoth's Wisdom is active and release the heavy attack. Use four sp2 attacks in Hoggoth's wisdom (If at three bars of power, charge a heavy attack mid combo and double tap block to consume a bar of power). Charge a heavy attack until Agamatto's Insight (fury) is active and launch two sp2 attacks followed by two sp1 attacks all in 'fury' blessing. Scarlet witch battlecast relic preferred. Offensive stat focus special damage.
A Tier: Solid for 35 7
These champions are hard hitters but need optimized gameplay, rotations, or masteries for a good win at 35 challenge rating disadvantage

Scarlet Witch -  

Purgatory - Flow of fight is sp3 sp2 sp2. Once in demonic rampage, do not use medium ending combos, only light ending. Best against cosmic tech and mutant champions Scarlet witch relic preferred. Offensive stat focus special damage. 

The Destroyer - Flow of fight is sp1 sp1 sp3 sp2 sp2. Intercept the opponent and punish special attacks to build destruction charges, sp1 will gain additional charges. Power gain will trigger once at 100, use sp3 as quickly as possible, power gain will still be active to quickly get to sp2 and throw for burst damage. With the time remaining build to sp2 once more and throw. Ghost rider relic preferred. Offensive stat focus special damage.

Scarlet Witch (Sigil) - 

Dragonman - Keep the opponent in the corner as much as possible. Build to sp3 and launch, after which throw sp2 three times in a row. After the second sp2 use a heavy attack to cause the 6 incinerates to deal burst damage. Easiest against a champion with short special attacks. Scarlet witch balltecast relic preferred. Offensive stat focus special damage.

Longshot - Against an opponent with many buffs, quickly build to two bars of power and launch sp2 with pure of heart active. Build good karma back up if possible and launch sp1. Rinse and repeat for a total of sp2 sp1 sp2 sp1. Iron fist battlecast relic preferred. Offensive stat focus special damage.

Spiral - Flow of fight is sp1 sp2 sp1 and one last special after (could be sp1 or sp2 but time will not be paused so it is what the timer allows). Alternate actions such as parry dex block medium light and heavy to gain fervor. After activating a special attack at max fervor of 15, swipe back and block a hit from the opponent before releasing block to reparry the opponent for an opening and prevent them from throwing a special attack, reparry is not required but helps tremendously. Use a MLLL combo before swipe up on block to trigger blades, opponent will be stunned and while it is possible to use a MLM followed by another combo (easiest when started with a light attack such as LLMLM) it is much safer for a less practiced player to use MM before starting a new combo. Activating the blades in the middle of a combo as such will place a vulnerability debuff which is very important for squeezing out damage in a tough fight and even a 40 CR disadvantage. Doctor doom statcast relic preferred, secondary attribute in physical penetration helps significantly. Offensive stat focus special damage or critical rating.
Videos
B Tier: Decent Damage 5
These champions have either unorthodox playstyle or specific requirements to win at a 35 challenge rating disadvantage such as relics, crit RNG, or opponent AI 

Rintrah - Combo the opponent until they are agianst the wall and use a light ending combo to root yourself. then combo the opponent and let them hit you to inflict ruptures. Once at two bars throw sp2 while still unstoppable. Repeat this for three sp2 attacks total. Juggernaut battlecast relic preferred. Offensive stat focus critical rating.

Mojo - 

White Tiger - 

The Hood - 

Nico Minoru - 
C Tier: Very Tight 35 5
These champions are the problem children and need a relatively smaller health pool opponent to have a chance at winning a 35 challenge rating disadvantage fight

Sasquatch - Against an opponent with buffs to be gained like jubilee, use heavy attack to stagger buffs which will feed mystic dispersion power gained. Build to and launch sp3 followed by as many medium ending combos while building to sp2. Mix in some heavy attacks when possible to gain power faster. Use sp2 when reached to consume rupture debuffs and deal additional damage based on how many were removed. In order to win a 35 CR disadvantage fight, three sp2 attacks must be used after sp3. Juggernaut battlecast relic preferred. Offensive stat focus critical rating.

America Chavez - Use heavy attacks chained from combos to gain negative zone dimension twice. Build to sp1 and launch after the second hit of a chained heavy attack to activate dark dimension and gain power from active dimensions. Build to relic and launch after the first hit of a heavy for utopian parallel, use another heavy (chained or not) and throw sp2 after the first hit for two additional utopian parallel dimension which will deal extra damage. Activate negative zone once more and throw sp1 for additional power, Then activate utopian parallel into relic into utopian parallel into sp2 to kill the opponent. Best when used against a champion who gains buffs that will expire during the fight feeding mystic dispersion like cyclops. Scarlet witch battlecast or iron fist battlecast relic preferred. Offensive stat focus special damage or critical rating. 

Manthing - Mystic dispersion mastery required. Build to nearly two bars of power and use sp1 twice. Use heavy atack to nullify all six buffs and throw sp3 with the power gained. Use heavy attack after sp3 to get back to sp2 and launch. Sp1 and heavy afterwards with the remaining time. Iron fist relic preferred. Offensive stat focus special damage.

Ghost Rider - 

Magik - 
D Tier: Near Impossible 3
These champions are the absolute worst in their class that can still technically pull through a 35 challenge rating disadvantage fight. They require either a fight like rocket raccoon or spider man stark enhanced and still need perfect AI to have a fighting chance

Blade (Stellar Forged) - One of the most difficult possible fights. Build to three bars of power, throw sp1 which will stun the opponent and sp3 very quickly after. After sp3 opponent will be stunned, combo them twice and quickly build to two bars to throw sp2 before torment expires. Build back to three bars before throwing sp1 followed by sp2 with the remaining time. Ghost rider relic required. Offensive stat focus special damage.

Isophyne - 

Diablo - 

Doctor Strange - 
F Tier: Incapable 13
These champions are incapable of a win in a 35 challenge rating disadvantage fight. Nothing is saving them
7* Locked 9
These champions are not available at the seven star rarity...at least not yet

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