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NO SAFE IS SAFE

Ant-Man
Black Cat
Shocker
Ant-ManThe final hit of Special Attack 1 gains +5% Attack Rating for each Debuff on the Opponent.

Black CatAttacks that steal the Calling Card are Guaranteed Critical Hits.

ShockerWhile Unblockable, gain +25% Attack Rating.

Unique Synergy: Does not stack with duplicate synergies.

INSIDIOUS

Shocker
Daredevil (Classic)
Doctor Octopus
Mysterio
Rhino
Scorpion

Synergy Champions: Gain +250 Critical Resistance, doubled when fighting #Spider-Verse Heroes.
Unique Synergy: Does not stack with duplicate synergies.

DON'T MOCK THE SHOCKER!

Shocker
Punisher
Spider-Man (Classic)
ShockerAt 50+ Vibro-Shock Charges, Defenders are 50% more likely to activate Special Attacks.

Solo Synergy: Only affects this Champion and does not stack.

INVASION OF THE BODY SNATCHERS

Baron Zemo
Doctor Doom
Apocalypse
Doctor Octopus

Synergy Members: Gain +300 Critical Rating when fighting Skill or Cosmic Opponents, +300 Block Proficiency when fighting Science or Tech Opponents, and +30% Regeneration Rate when fighting Mystic or Mutant Opponents. Gain all bonuses when fighting Superior Opponents.
Unique Synergy: Does not stack with duplicate synergies.

GOO PLATOON

Baron Zemo
Abomination (Immortal)
Man-Thing
Symbiote Supreme
Toad

Synergy Members: Activating a Special Attack grants a non-stacking Vicious Buff increasing the potency of Damage Over Time Debuffs by 50% for 10 seconds.
Unique Synergy: Does not stack with duplicate synergies.

BOOGIE BOOGIE UPRISING

Baron Zemo
Deadpool
Mantis
Spider-Man (Symbiote)
Star-Lord

Synergy Members: Dodging back and holding Block activates a 1.2 second timer. Releasing Block just as the timer expires grants a Jiggy With It Buff for 20 seconds, increasing Critical Rating by +150 and granting an Unstoppable Passive while Dodging backwards or Dashing forwards.
Unique Synergy: Does not stack with duplicate synergies.

JUSTICE, LIKE LIGHTNING…

Baron Zemo

Thunderbolt Champions: Gain +3% Perfect Block chance and take 5% less damage from Special Attacks for each #Thunderbolt on the team. These bonuses are doubled when fighting #Villains.
Unique Synergy: Does not stack with duplicate synergies.

THE WORTHY

Absorbing Man
Thor (Jane Foster)
Thor
Absorbing ManThe second Medium Attack inflicts an Armor Break Debuff, reducing Armor by 500 for 9 seconds. Max stacks: 5

Thor (Jane Foster)When facing Cosmic champions, The Mighty Thor inflicts Degeneration effects instead of personal Shocks, which count as Shocks for her abilities.

ThorThor’s Heavy attack inflicts an Armor Break Debuff, reducing Armor by 1800 for 4.5 seconds. Max stacks: 2

Unique Synergy: Does not stack with duplicate synergies.

THE GREEN DOOR

Absorbing Man
Abomination (Immortal)
Hulk (Immortal)
Absorbing ManGain Immunity to all Poison effects, and Omni-Morph Forms last 3 seconds longer.

Abomination (Immortal)Gain 250 Energy Resistance for each Poison effect on himself.

Hulk (Immortal)Personal Immortality effects gain +20% Ability Accuracy.

Unique Synergy: Does not stack with duplicate synergies.

TOUR GUIDE

Baron Zemo
Captain America (Sam Wilson)
Falcon
Winter Soldier
Baron ZemoGain +500 Armor Rating and +500 Critical Damage Rating.

Captain America (Sam Wilson)Gain +25% Debuff duration and +500 Critical Damage Rating.

FalconGain +25% Debuff duration and +500 Critical Damage Rating.

Winter SoldierGain +25% Debuff duration and +500 Armor Rating.

Unique Synergy: Does not stack with duplicate synergies.

STOLE MY SHTICK

Baron Zemo
Phoenix
Baron ZemoBullet hits during Zemo’s Medium Attacks and Special Attack 2 inflict Incinerate Debuffs, dealing 20% of Attack Rating as Energy Damage over 6 seconds. Incinerate removes Perfect Block chance and reduces Block Proficiency by 50%.

PhoenixFury Buffs gain 20% increased potency.

Unique Synergy: Does not stack with duplicate synergies.

HOUSE OF ZEMO

Baron Zemo
Baron ZemoGain +50% Bleed potency for each other Baron Zemo on the team. Additionally, gain +5% Bleed potency for each rank in the Deep Wounds Mastery.

Only affects this Champion and does not stack.

SINS OF THE FATHER

Absorbing Man
Daredevil (Hell's Kitchen)
Absorbing ManWhile at or below 15 Combo Meter, gain 1000 Block Proficiency, and while above, gain 1000 Critical Rating.

Daredevil (Hell's Kitchen)Personal Buffs last for an additional 7 seconds.

Unique Synergy: Does not stack with duplicate synergies.

ROGUE'S ROMANCE

Absorbing Man
Titania
Absorbing ManMedium and Heavy Attacks gain 600 Critical Damage Rating.

TitaniaGain Immunity to Bleed effects.

Unique Synergy: Does not stack with duplicate synergies.

HANDS-ON APPROACH

Rogue
Absorbing Man
RogueThe timer for Rogue's Replicated Buffs is paused during the Opponent's Special Attacks.

Absorbing ManReduce the duration of Non-Damaging Debuffs other than Stuns by 50%.

Unique Synergy: Does not stack with duplicate synergies.

DARKNESS INSIDE YOU

Knull
Sentry
Void
The Hood
KnullWhile the opponent is suffering from 12+ Armor Breaks, Knull gains an indefinite Energize Buff.

Solo: Only affects this Champion and does not stack.

YOUR FATE IS MINE

Apocalypse
Cable
Kang the Conqueror
Mister Sinister
ApocalypseStart the first fight in a quest with maximum Genetic Code.

CableIncinerate Debuffs gain +150% Potency. Additionally, Heavy Attacks now inflict Degeneration on each hit and their stack limit is removed.

Kang the ConquerorEvery 4 seconds, Kang Gains an indefinite Fury Buff granting 20% Attack Rating. This ends when reaching 20 stacks of Fury.

Mister SinisterDegeneration Debuffs gain +50% Potency.

Unique Synergy: Does not stack with duplicate synergies.

YOU'RE TANGLING WITH THE WRONG X-MEN

Jubilee
Cyclops (Blue Team)
Phoenix
Jubilee+900 Energy Resistance.

Cyclops (Blue Team)+15% Attack Rating.

Phoenix+15% Attack Rating.

Unique Synergy: Does not stack with duplicate synergies.

YOU'RE BUSTED!

Misty Knight
Elsa Bloodstone
Misty KnightWhen Misty gains a Cryogenic Charge, there is a 30% chance of inflicting a Busted Debuff on the opponent, increasing potency of Coldsnap by 50% for 16 seconds.

Elsa BloodstoneAll Busted Debuffs have their durations increased by 15%.

Unique Synergy: Does not stack with duplicate synergies.

YOU STILL USIN' SCRAP FOR WEAPONS, BOY?

Rocket Raccoon
Yondu
Rocket RaccoonMax Scrap Metal increased to 60.

YonduSpecial Attack 2 Fury duration increased by 50%.

Unique Synergy: Does not stack with duplicate synergies.