Reset

Apocalypse
Stryfe
BIG BAD DAD
Apocalypse: Activating Special Attack 1 or 2 increases the potency of personal burst damage by +25%, this can stack up to +300% max.

Stryfe: The final hit of Special Attack 2 pauses all Shock effects on the Opponent for 4 seconds. If this champion is a Horseman of Apocalypse become Passively Unblockable as long as 20 Telepathic Charges are active.
Unique Synergy: Does not stack with duplicate synergies.
Maestro
Red Skull
Kang the Conqueror
Thanos
Big Bads
Synergy Champions: Gain +100 Armor Rating, +100 Critical Rating, +100 Critical Damage Rating, and +3% Perfect Block Chance, doubled when fighting the final node in a Quest.
Unique Synergy: Does not stack with duplicate synergies.
Kraven
Beast
Dragon Man
Sasquatch
BIG GAME
Synergy Champions: Stunning a Stun Immune Champion will instead inflict a non-stacking Concussion Debuff, reducing Ability Accuracy by 60% for 5 second(s).
Unique Synergy: Does not stack with duplicate synergies.
Elsa Bloodstone
Tigra
BIG GAME HUNTERS
Elsa Bloodstone: Enhanced Ammunition Debuffs last 4.0 seconds longer. Additionally, when fighting on the last node in a quest, Opponents cannot activate True Strike or True Accuracy abilities.

Tigra: When fighting #Large and #XL Champions, increase the duration of Rupture effects by 25%.
Unique Synergy: Does not stack with duplicate Synergies.
Werewolf By Night
Man-Thing
Big Game Monsters
Werewolf By Night: Chilling Howl inflicts a 5% Physical Vulnerability Debuff for 25 seconds. Max stacks: 3.
Solo Synergy: Only affects this Champion and does not stack.
Ant-Man
Doctor Octopus
BIOCHEMISTRY
Ant-Man: When causing a Hit to Glance, reflect 40% of Physical Damage done, by attacks that make Contact.

Doctor Octopus: Start with 40 Chemistry Research.
Unique Synergy: Does not stack with duplicate synergies.
Darkhawk
Sauron
Captain America (Sam Wilson)
Falcon
BIRD TELEPATHY
Darkhawk: Each hit of Special 1 has a 10% chance to refresh the current active mode.

Sauron: When performing a Well-Timed Block, 30% chance gain a Physical Resistance Buff. If there are more Physical Resistance Buffs than Energy Resistance, gain Energy Resistance instead. These Buffs increase their corresponding Resistance by +[520, 537] and last for 10 second(s).
Captain America (Sam Wilson), Falcon: Opponent Combat Power Rate is decreased by 40% while Lock-On is on a Cooldown.
Unique Synergy: Does not stack with duplicate synergies.
Darkhawk
Vulture
Falcon
Hawkeye
BIRDS OF PREY
Darkhawk, Vulture, Falcon, Hawkeye: + 5% Critical Rating and Damaging Debuffs are 40% stronger.
Unique Synergy: Does not stack with duplicate synergies.
Professor X
BIRTHRIGHT
All Mutants and X-Men except Professor X: +25% Special Attack Damage for each Cerebro Charge. Max 100%.
Unique Synergy: Does not stack with duplicate synergies.
Bullseye
Daredevil (Classic)
Daredevil (Hell's Kitchen)
Elektra
Black and White and Red all over
Bullseye: If Daredevil or Daredevil (Hell’s Kitchen) are Knocked Out, start each fight with an indefinite 10% Cruelty Buff.

Daredevil (Classic): If Elektra is Knocked Out, start each fight with an indefinite 20% Fury Buff.

Daredevil (Hell's Kitchen): If Elektra is Knocked Out, start each fight with an indefinite 20% Fury Buff.

Elektra: If Bullseye is Knocked Out, start each fight with an indefinite 20% Precision Buff.
Unique Synergy: Does not stack with duplicate synergies.
Gorr
Hercules
Ikaris
Sersi
BLOOD AND GORR
Gorr: The recovery reduction from Poison effects on Gorr is 50% less effective.
Solo Synergy: Only affects this Champion and does not stack.
Mister Sinister
Cyclops (Blue Team)
Cyclops (New Xavier School)
Phoenix
BLOOD LINES
Mister Sinister, Cyclops (Both), Phoenix: Special Attacks have +20% Critical Rating and gain True Strike, ignoring all Armor, Resistances, Evasion, and Auto Block.
Unique Synergy: Does not stack with duplicate synergies.
Sorcerer Supreme
Archangel
Nebula
The Champion
BLUETIFUL PEOPLE
All Champions gain +[250, 325, 400] Block Penetration
Baron Zemo
Deadpool
Mantis
Spider-Man (Symbiote)
Star-Lord
BOOGIE BOOGIE UPRISING
Synergy Members: Dodging back and holding Block activates a 1.2 second timer. Releasing Block just as the timer expires grants a Jiggy With It Buff for 20 seconds, increasing Critical Rating by +150 and granting an Unstoppable Passive while Dodging backwards or Dashing forwards.
Unique Synergy: Does not stack with duplicate synergies.
Northstar
Iceman
Born This Way
Northstar: Heavy Attacks remove all stacks of personal pause to deal a burst of 5% of Attack Rating in Physical Damage per personal Reverb and Prowess effect on Northstar.

Iceman: Intercepts and Dash Attacks inflict a Frostbite Passive and cause the cooldown for Ice Armor to briefly expire faster.
Unique Synergy: Does not stack with duplicate synergies.
QuickSilver
Magneto
Professor X
Wolverine
Beast
BREAK OUT
QuickSilver: Whiplash damage increases by 25%.
Magneto,Professor X,Wolverine,Beast: Reduce the Opponent’s Purify Ability Accuracy by -100% for 3 second(s) after a Well-Timed Block.
Unique Synergy: Does not stack with duplicate synergies.
Sandman
Mantis
BRING ME A DREAM
Sandman: After Special Attack 3, Sandman gains a Fury Passive granting 30% Attack Rating for 10 seconds.

Mantis: Gain a True Accuracy Buff for 10 seconds when the Opponent is inflicted with Sleep.
Unique Synergy: Does not stack with duplicate synergies.
Psylocke
Apocalypse
BRINGER OF DEATH - I
Psylocke: Basic Attacks have a 30% chance to grant a psi-charge and each psi-charge grants +5% Critical Rating.
Unique Synergy: Does not stack with duplicate synergies.
If this champion is a Horseman of Apocalypse Gain +50% Critical Damage Rating and +50% Attack Rating when striking an Opponent at 0 Power.
Gambit
Apocalypse
BRINGER OF DEATH - II
Gambit: Each time a Kinetic Charge is gained there is a 70% chance to gain an additional one. Cooldown 0.8 seconds.
Unique Synergy: Does not stack with duplicate synergies.
If this champion is a Horseman of Apocalypse Each Kinetic Charge grants 10% Perfect Block Chance up to a max of 100%.
Wolverine
Apocalypse
BRINGER OF DEATH - III
Wolverine: Personal Bleeds have a chance based on Critical Rating to be Critical Bleeds dealing damage based on Critical Damage Rating.
Unique Synergy: Does not stack with duplicate synergies.
If this champion is a Horseman of Apocalypse Gain +30% Critical Rating and +40% Critical Damage Rating.