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Lady Deathstrike
Old Man Logan
Wolverine
Wolverine (Weapon X)
TRUE HATRED
Lady Deathstrike: When defeating #X-Men, gain a Cross-Fight Fury Buff, increasing Attack Rating by 20%. The Fury Buff potency increases by 200% when defeating any Wolverine.

Old Man Logan: Personal Fury Buffs last 50% longer, and all Fury Buffs are paused during his or the Opponent’s Specials.

Wolverine: When any Bleed Debuff is Purified, inflict a Passive Bleed with 70% of the damage and same duration.

Wolverine (Weapon X): When any Bleed Debuff is Purified, inflict a Passive Bleed with 70% of the damage and same duration.
Unique Synergy: Does not stack with duplicate synergies.
Hulkling
Wiccan
TRUE LOVE
Hulkling: Hulkling is Stun Immune while he has at least 3 Pierce Buffs.
Unique Synergy: Does not stack with duplicate synergies.
Northstar
Sasquatch
Guardian
True North
Northstar: While Speed Burst is ready to be activated, Northstar’s Combat Power Rate is increased by 15%.

Sasquatch: When immune to a Stun or Frostbite effect, or when inflicted with Coldsnap Debuff, pause Wrath of Tanaraq for 5 seconds.

Guardian: A Perfect Block briefly briefly pauses any Force Field charges that are expiring.
Unique Synergy: Does not stack with duplicate synergies.
Guardian
TRUE NORTHERN DEFENSE
All Champions except Guardian: +[500, 750, 1000, 1250] Block Proficiency.
Unique Synergy: Does not stack with duplicate synergies.
Toad
Magneto
TRULY DEVOTED
Toad: While Paralytic Secretion is active, gain an Unstoppable Buff for 5 seconds when charging a Heavy Attack. Cooldown 12 seconds.
Solo Synergy: Only affects this Champion and does not stack.
Iron Man (Infamous)
Human Torch
Mister Fantastic
Thing
TRUST ISSUES
Iron Man (Infamous): Gains +4900 Critical Rating while the Opponent has 2 or more Bars of Power.

Human Torch: Chance to Incinerate when Struck increased by a flat 100%.

Mister Fantastic: Imprison the Opponent’s Soul at the start of the fight, reducing their chance to activate Buffs by 100% for 15 seconds.

Thing: When Rock Stacks are removed, Thing gains an extra Fury Passive.
Unique Synergy: Does not stack with duplicate synergies.
Human Torch
Thing
TURN UP THE HEAT
Human Torch: Human Torch starts the fight with 2 Smoulder Passives, and his Temperature increases faster while charging a Heavy Attack.
Unique Synergy: Does not stack with duplicate synergies.
Diablo
Dormammu
Mangog
Symbiote Supreme
TWISTED ARCANISTS
Diablo: Philosopher’s Mix is Paused during Diablo’s Special Attacks.

Dormammu: After using an Imbued attack, gain 40 Dark Energy.

Mangog: While Enraged, gain +10% Attack Rating.

Symbiote Supreme: +1% Attack Rating for each Stagger on the opponent.
Unique Synergy: Does not stack with duplicate synergies.
Thanos (Deathless)
Vision (Deathless)
Twisted Insight
Vision (Deathless): Gain Immunity to Reverse Controls. Additionally, after the Opponent activates a Special Attack, Vision Power Burns 1 Bar of their Power. If this Burns at least 50% of a Bar of Power, gain 1 personal Phase Charge.
Unique Synergy: Does not stack with duplicate synergies.
Arnim Zola
Red Skull
Punisher 2099
Crossbones
Taskmaster
Captain America
Two More Shall Take Its Place
Captain America: While in a fight, Captain America counts as #Hydra and a #Villain instead of a #Hero.
#Hydra Champions: Start each fight with an indefinite Lying In Hate Passive, increasing Attack Rating by +10%. When struck by a Special Attack 1 or 2, Lying in Hate is consumed to grant an Indestructible Passive for the remainder of the Special Attack.
Unique Synergy: Does not stack with duplicate synergies.
Count Nefaria
Iron Man
Two Sides of a Coin
Count Nefaria: Whenever an Energy Build Up is inflicted, also inflict a 15% Decelerate Debuff lasting 18 seconds.

Iron Man: Whenever a Prowess is Invalidated, gain an Armor Up Buff.
Unique Synergy: Does not stack with duplicate synergies.
Guillotine (Deathless)
Guillotine
TWO SIDES OF THE COIN
Guillotine (Deathless): Souls last 30% longer and are paused during either Champion's Special Attacks.

Guillotine: The potency of healing from damage taken by the Opponent is increased by 66.6%.
Unique Synergy: Does not stack with duplicate synergies.
White Tiger
Iron Fist
Luke Cage
Nova
Spider-Man (Classic)
Ultimate Teammates
Synergy Champions: Gain +4% Perfect Block Chance for each unique Synergy Champion on the team. If all Synergy Champions are present, also gain +30% Attack Rating.
Unique Synergy: Does not stack with duplicate synergies.
Thanos (Deathless)
Guillotine (Deathless)
King Groot (Deathless)
Vision (Deathless)
She-Hulk (Deathless)
Umbral Vanguard
Guillotine (Deathless): On activation, Special 1 inflicts a non-stacking 150% Neutralize Passive for 15 seconds.

King Groot (Deathless): When struck by an Unblockable attack, spend one Fury Buff to gain an Unstoppable Passive for 3 seconds.

Vision (Deathless): Personal Fury max stack increases by +6, and their pause is increased by +5 seconds.

She-Hulk (Deathless): Punishing the Opponent’s Special or Heavy Attacks grants a Grit Buff for 10 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Synergy Champions: In the Necropolis, gain +50 Vengeance Charges. If all Champions are present:
Rintrah
M.O.D.O.K.
UNACCEPTABULL
Rintrah: Inflict 4 Rupture Debuffs dealing 15% Attack Rating as Physical Damage over 15 second(s) on last hit of Special 1.

M.O.D.O.K.: On landing a Critical Hit, if both a personal Incinerate and Bleed on Opponent, pause them for 6 second(s).
Unique Synergy: Does not stack with duplicate synergies.
Havok
Captain America
Wasp
UNCANNY AVENGERS
Havok: Well Timed Blocks grant +1 Plasma Charge.

Captain America: Passively increases Attack by 20% of Base Attack when Striking a Debuffed Opponent.

Wasp: When Wasp charges a Heavy Attack while hitting with a Basic Attack Combo, she gains a Passive Fury Effect increasing her Attack by 50% of her Base Attack for 3 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Morningstar
Purgatory
UNCHAINED
Morningstar: +50% Ability Power Rate while below 1 Bar of Power.

Purgatory: Inflict a Soul Neutralize every 25 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Storm (Pyramid X)
Storm
UNDER THE WEATHER
Storm (Pyramid X): Alternate Tempests activated by Storm's Special 3 last 8 seconds longer.

Storm: Gain Immunity to Incinerate and Coldsnap effects. Each time an Immunity prevents one of these effects, gain 2 Prowess Buff(s).
Unique Synergy: Does not stack with duplicate Synergies.
Captain Britain
Unstoppable Colossus
Thing
UNDERSTANDING EVIL
All Non-Villian Champions, gain 10% Attack Rating, 5% Physical Resistance, 5% Energy Resistance vs. Villains.
Unique Synergy: Does not stack with duplicate synergies.
Diablo
Kingpin
Loki
Red Skull
UNENDING AMBITION
Diablo: Personal Poison Debuffs become Passive and gain +10% Potency.

Kingpin: Gain 1 Rage each time the opponent Nullifies a Buff.

Loki: +35% Curse Debuff duration.

Red Skull: 35% Shock Debuff Potency.
Unique Synergy: Does not stack with duplicate synergies.