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Werewolf By Night
Morbius
Ghost Rider
Elsa Bloodstone
Man-Thing
Punisher
United By Chance
Werewolf By Night: Start each fight with a 10% Vicious Passive for 30 seconds.

Morbius: Start each fight with a 10% Vicious Passive for 30 seconds.

Ghost Rider: Start each fight with a 10% Vicious Passive for 30 seconds.

Elsa Bloodstone: Start each fight with a 10% Vicious Passive for 30 seconds.

Man-Thing: Start each fight with a 10% Vicious Passive for 30 seconds.

Punisher: Gain this synergy’s bonus after taking a Lethal Blow during the Quest.
Legion of Monsters Champions (Morbius, Ghost Rider, Elsa Bloodstone, Man-Thing): Start each fight with a 10% Vicious Passive for 30 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Ant-Man
Ronin
UNLIKELY COMBINATION
Ant-Man: Increase the Potency of Poisons by 20%.

Ronin: Gain +25% Block Proficiency in Guard Stance.
Unique Synergy: Does not stack with duplicate synergies.
Proxima Midnight
Nebula
UNMERCIFUL PUNISHMENT
Proxima Midnight: When True Accuracy is active, her Attack Rating is increased by 15%.

Nebula: Starts the fight with 10 Electroshock Charges.
Unique Synergy: Does not stack with duplicate Synergies.
Sersi
Captain America
Captain America (Infinity War)
UNREQUITED ROMANCE
Sersi: Start the fight with an indefinite Armor Up increasing Armor Rating by [30, 60, 100].
Solo Synergy: Only affects this Champion and does not stack.
Sabretooth
Old Man Logan
UNTAMED FORCE
Sabretooth: 20% chance for his low-kick first Medium Attack to be Unblockable. Additionally, If the opponent activates an unstoppable effect as a result of this attack, it expires instantly.

Old Man Logan: +120% Regeneration Rate when hitting opponents.
Unique Synergy: Does not stack with duplicate synergies.
Shuri
Black Panther
Black Panther (Civil War)
USAPHO
Synergy Members: Gain +10% Health and +10% Shock and Bleed potency.
Unique Synergy: Does not stack with duplicate synergies.
Shuri
Attuma
Namor
UTSHABA
Synergy Members: Start each fight with 10 indefinite Precision Passives. These don't count as Precisions and are consumed by Light and Medium hits to become Guaranteed Critical Hits.
Unique Synergy: Does not stack with duplicate synergies.
Knull
Red Goblin
Symbiote Supreme
Venom
Venom The Duck
VESSELS OF DARKNESS
Knull: When the Opponent is immune to an effect, Knull gains a Fury Buff, increasing Attack Rating by 35% for 16 seconds. Max 1 stack(s).
Solo: Only affects this Champion and does not stack.
Gentle
Captain America (Sam Wilson)
Captain America (Infinity War)
Misty Knight
Vibranium Club
Gentle: Increase the Ability Accuracy of Muscle Mass by 25%.

Captain America (Sam Wilson): Increase the Ability Accuracy of personal Armor Ups by 25%.

Captain America (Infinity War): Increase the Ability Accuracy of personal Debuffs by 25%.

Misty Knight: Increase the Ability Accuracy of personal Purifies and Evades by 25%.
Kitty Pryde
Tigra
VICIOUS KITTY
Kitty Pryde: While 10+ Prowess are active, become Passively Unblockable while Phased.

Tigra: Neutralize effects last +35% longer.
Unique Synergy: Does not stack with duplicate synergies.
Galan
Red Goblin
Venom The Duck
VILLAINS ACROSS THE COSMOS
Red Goblin: If this Champion is a Herald and below 41% health, enter Frenzy indefinitely. This is removed if Red Goblin goes above 41% health.

Venom The Duck: If this Champion is a Herald, ending a Combo with a Light Attack will remove all active Symbiote Buffs and increase Aberration by 50%. This ability only activates while 1 Buff is active.
Unique Synergy: Does not stack with duplicate synergies.
Viv Vision
Valkyrie
Venom
Vision (Aarkus)
Void
Vulture
VVVVVV
Synergy Champions: Personal Buffs and Debuffs gain +10% potency.
Unique Synergy: Does not stack with duplicate synergies.
Black Panther (Civil War)
Killmonger
WAKANDA LEADERSHIP
Black Panther (Civil War): Well Timed Blocks provides a +30% Fury Buff for 15 seconds.

Killmonger: Starts the fight with 3 of his Indestructible and Counterpunch Charges.
Unique Synergy: Does not stack with duplicate Synergies.
Gentle
Storm
Black Panther
Wakanda Mutant
Gentle: Increase the potency of Reverbs by 20%.

Storm: When the Opponent Purifies a Debuff, gain 1 additional Prowess.

Black Panther: Intercepts are Guaranteed Critical Hits.
Unique Synergy: Does not stack with duplicate synergies.
Ironheart
Black Panther
Shuri
Wakanda Strong
Ironheart: Final hit of Special Attack 1 grants an Unstoppable Buff for 8 seconds.

Black Panther: First and final hits of Special Attack 1 have a 100% chance to be a critical hit.

Shuri: Special Attack 1 hits have a 30% chance to inflict a personal Shock Debuff.
Unique Synergy: Does not stack with duplicate synergies.
Iron Man (Infinity War)
Black Panther (Civil War)
Killmonger
WAKANDAN INSIGHT
Everyone: Each active Armor effect also increases Critical Resistance by 12%.
Unique Synergy: Does not stack with duplicate synergies.
Vox
Sandman
Mantis
WAKE ME UP
Synergy Champions: Incoming Sleep effects gain 30% increased duration, but grant a 50% Fury Buff for 10 seconds when they expire.
Unique Synergy: Does not stack with duplicate synergies.
Hela
Odin
WARMONGER
Hela: While charging her Heavy Attack, Hela gains twice as many Fury Buffs.

Odin: +10% Attack Rating when fighting the final node of a quest.
Unique Synergy: Does not stack with duplicate synergies.
Morningstar
Angela
Magik
WARRIOR QUEENS
Morningstar: Buffs last 20% longer.

Angela: Buffs last 20% longer.

Magik: 500 Critical Rating and +500 Critical Damage while Limbo is active.
Unique Synergy: Does not stack with duplicate synergies.
Black Panther
Iron Fist
Iron Fist (Immortal)
WARRIORS
Black Panther: Start the fight with 3 Inactive Panther's Might Charges.

Iron Fist: +25% Armor break Debuff potency.

Iron Fist (Immortal): +25% Armor break Debuff potency.
Unique Synergy: Does not stack with duplicate synergies.