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Mantis
Rocket Raccoon
THIS ONE THINKS VIOLENCE IS NOT THE SOLUTION
Mantis: While at least 1 personal Cruelty Buff is active, gain a Precision Passive, increasing Critical Rating by 350.

Rocket Raccoon: Inflicting Power Drains with Special 1 now consumes 12 Scrap Metal instead of 15.
Unique Synergy: Does not stack with duplicate synergies.
Mantis
Drax
THIS ONE WON'T LET ANYTHING GO OVER YOUR HEAD!
Mantis: Mantis' Sleep inflicted by charging Heavy Attack has its duration increased by 0.5 seconds flat.

Drax: Drax can now Parry non-contact hits.
Unique Synergy: Does not stack with duplicate synergies.
Beta Ray Bill
Thor (Ragnarok)
Thor (Jane Foster)
Thors
Beta Ray Bill: The final hit of Special Attack 1 has a 33% chance to inflict a Stun Debuff for 3 seconds.

Thor (Ragnarok): Start each fight with a Thunder God’s Wrath Passive for 10 seconds.

Thor (Jane Foster): If the Opponent is not Shocked, Basic Attacks have a 10% chance to inflict a Shock Debuff, dealing 85% of Attack as Energy Damage over 4 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Isophyne
Gladiator
Those that are truly confident
Isophyne: Isophyne starts with 4 Ego and their Max Ego is increased by +2.

Gladiator: Heavy Attacks grant +1 additional Confidence Buff. Furthermore, while the Opponent is suffering from Intimidate, Dashing forward inflicts a Root Passive for the duration of the Dash. Cooldown: 8 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Kitty Pryde
Emma Frost
THROUGH THICK AND THIN
Kitty Pryde: Become Immune to reverse controls, and each time this immunity is triggered gain +1 personal Prowess. Cooldown 0.8 seconds.

Emma Frost: Gain +20% Attack Rating in diamond form and gain +20% Combat Power Rate in telepathic form.
Unique Synergy: Does not stack with duplicate synergies.
Taskmaster
Winter Soldier
THUNDERBOLTS
Taskmaster: Current Exploit Weakness target Attack has a 20% chance to become Unblockable.

Winter Soldier: Wintersoldier’s EMP Upgrade gains a flat +5% chance to trigger.
Unique Synergy: Does not stack with duplicate synergies.
Luke Cage
Red Hulk
Agent Venom
Elektra
Iron Patriot
Juggernaut
THUNDERBOLTS
All Champions take [5, 10, 15]% less Special Damage
Namor
Moon Knight
TIDE TO GO
Namor: Under a Full or New Moon, attacking or being attacked by Bleeding Opponents grants 5% of a bar of Power with each Strike. As the Moon waxes and wanes, Attack Rating is increased by +15%.

Moon Knight: Under a Full or New Moon, Combat Power Rate is increased by 10%. As the Moon waxes and wanes, Bleed and Fury potency is increased by 15%.
Unique Synergy: Does not stack with duplicate synergies.
Scarlet Witch (Sigil)
Vision
Vision (Age of Ultron)
Till Infinity Do Us Part:
Scarlet Witch (Sigil): When Chaos Surge activates, 8% chance to gain an Aptitude Buff increasing Fury, Precision, and Armor Up Buffs by 30% for 18 seconds.

Vision: Landing a Heavy Attack on an Opponent suffering Heal Block grants a non-stacking Fury, increasing Attack Rating by 1000 for 15 seconds.

Vision (Age of Ultron): Landing a Heavy Attack on an Opponent suffering Heal Block grants a non-stacking Fury, increasing Attack Rating by 1000 for 15 seconds.
Unique Synergy: Does not stack with duplicate Synergies.
Anti-Venom
Doctor Octopus
Spider Man 2099
TIME TRAVELERS
Anti-Venom: For the first 10 second(s) of the fight the Opponent is immune to Buffs.

Doctor Octopus: When dealing damage per Breakthrough removed on a Heavy Attack, 25% chance per Breakthrough to inflict another burst of damage dealing Attack Rating in damage.

Spider Man 2099: On the start of the fight, inflict a Wither Debuff on the Opponent with a potency of 125% for 15 second(s).
Unique Synergy: Does not stack with duplicate synergies.
Mordo
Doctor Voodoo
Sorcerer Supreme
Wong
TOO MANY SORCERERS...
Mordo: While fighting Mystic Champions, Mordo is Immune to Nullify and Fate Seal.
Synergy Champions: +6% Attack Rating.
Unique Synergy: Does not stack with duplicate synergies.
Morbius
Werewolf By Night
Elsa Bloodstone
Man-Thing
Ghost Rider
Punisher
Tormented Souls
Morbius: At the start of each fight, inflict a 35% Torment Passive for 30 seconds.

Werewolf By Night: At the start of each fight, inflict a 35% Torment Passive for 30 seconds.

Elsa Bloodstone: At the start of each fight, inflict a 35% Torment Passive for 30 seconds.

Man-Thing: At the start of each fight, inflict a 35% Torment Passive for 30 seconds.

Ghost Rider: At the start of each fight, inflict a 35% Torment Passive for 30 seconds.
Legion of Monsters Champions: At the start of each fight, inflict a 35% Torment Passive for 30 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Spiral
Mojo
Longshot
Tormentee to Tormentor
Spiral: Weapon Attacks Instantly Regenerate 1 Health for each Fervor Spiral has gained consecutively, up to 50.

Mojo: Prompts expire 5% slower per million Followers.

Longshot: The first hit of Longshot’s Heavy Attack prevents him from using his Special Attack 3 until the Heavy finishes. Once triggered, disabled until Special Attack 3 is used.
Unique Synergy: Does not stack with duplicate synergies.
Nova
Annihilus
TOTAL ANNIHILATION
Nova: Gain +40% Perfect Block chance when triggering Auto-Block.

Annihilus: +65% Physical Resistance while Unstoppable.
Unique Synergy: Does not stack with duplicate synergies.
The Champion
Luke Cage
TOUGH BRAWLERS
The Champion: The Champion is Unstoppable when using a Light and Medium Attack.

Luke Cage: +35% chance to inflict Debuffs as long as Luke Cage never dashes back in a fight.
Unique Synergy: Does not stack with duplicate Synergies.
Baron Zemo
Captain America (Sam Wilson)
Falcon
Winter Soldier
TOUR GUIDE
Baron Zemo: Gain +500 Armor Rating and +500 Critical Damage Rating.

Captain America (Sam Wilson): Gain +25% Debuff duration and +500 Critical Damage Rating.

Falcon: Gain +25% Debuff duration and +500 Critical Damage Rating.

Winter Soldier: Gain +25% Debuff duration and +500 Armor Rating.
Unique Synergy: Does not stack with duplicate synergies.
Toad
Scarlet Witch (Classic)
Scarlet Witch (Sigil)
TOXIC LOVE
Toad: +15% Combat Power Rate while Paralytic Secretion is active.
Solo Synergy: Only affects this Champion and does not stack.
Jabari Panther
Black Panther
Black Panther (Civil War)
Killmonger
TRIBAL WARFARE
Jabari Panther: Gain an additional Cleanse Passive whenever one would be gained.

Black Panther: Critical Hits have an 80% chance to inflict a Bleed Debuff, dealing 50% of their Attack in damage over 4 second(s).

Black Panther (Civil War): Critical Hits have an 80% chance to inflict a Bleed Debuff, dealing 50% of their Attack in damage over 4 second(s).

Killmonger: Well-Timed Blocks grant a non-stacking Precision Buff for 4 second(s), increasing Critical Rating by +700.
Unique Synergy: Does not stack with duplicate synergies.
Vox
Knull
TRIPLE EDGE
Synergy Champions: Lose an additional 5% Health from the Double Edge Mastery, but it grants an additional +10% Attack Rating.
Unique Synergy: Does not stack with duplicate synergies.
Wolverine (Weapon X)
Platinum Pool
Kang the Conqueror
Thanos
TROPHY CASE
Wolverine (Weapon X): Start the fight with 5 Rage charges.

Platinum Pool: Start the fight with a Fury Buff, granting 50% of your Base Attack for 15 Seconds.

Kang the Conqueror: Start the fight with a Fury Buff, granting 50% of your Base Attack for 15 Seconds.

Thanos: Start the fight with a Fury Buff, granting 50% of your Base Attack for 15 Seconds.
Unique Synergy: Does not stack with duplicate synergies.