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Silver Sable
Prowler
Sandman
The Outlaws
Silver Sable: Increase the duration of personal Disorient effects by +5 seconds.

Prowler: While Prowler’s personal Pursuit Passive is active, attacks that cause Evade abilities to fail grant a non-stacking +50% Fury Buff for 20 seconds.

Sandman: While Unstable and performing a Heavy Attack, personal Debuffs are paused.
Unique Synergy: Does not stack with duplicate synergies.
Hulkling
Toad
THE PRINCE AND THE FROG
Hulkling: The number of Pierce Buffs needed to trigger Peak Transformation’s Unblockable Buff is reduced by 1.

Toad: When the Opponent gains a Poison effect, if they have 5 Poison effects, refresh Toad’s personal Slow Debuff.
Unique Synergy: Does not stack with duplicate synergies.
Yelena Belova
Black Widow (Deadly Origin)
Black Widow
The Red Room
Yelena Belova: While the Opponent is suffering from a Bleed Vulnerability Debuff, they are also inflicted with a non-stacking 25% Sabotage Debuff. This Sabotage deals Direct Damage by inflicting Yelena’s Instant Bleed.

Black Widow (Deadly Origin): Start each fight with an indefinite 35% Endurance Passive.

Black Widow: Start each fight with an indefinite 35% Endurance Passive.
Unique Synergy: Does not stack with duplicate synergies.
Patriot
Falcon
Captain America (Sam Wilson)
The Same Thing I Want
Patriot: Personal Vigilance effects are paused during Patriot’s Special Attacks and Strikers.

Falcon: Personal Bleeds are paused during Heavy Attacks and Special Attack 1.

Captain America (Sam Wilson): Intercepting the Opponent grants a personal Bulwark Buff without consuming or requiring an Armor Up.
Unique Synergy: Does not stack with duplicate synergies.
Dust
Jubilee
The Shallow Twins
Dust: Whenever the Opponent activates a Purify, there is a 35% chance to inflict 1 Sand Passive.

Jubilee: When Jubilee’s Opponent Purifies a Debuff, pause the current Fireworks Surge for 3.5 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Spider-Man (Supreme)
Sorcerer Supreme
Symbiote Supreme
THE SUPREMES
Spider-Man (Supreme): Granting Spider-Seal Buffs to an Opponent that has no Buff or only Spider-Seal Buffs, inflicts a burst of 10% of Attack as Energy Damage.

Sorcerer Supreme: Special Attacks inflict an Energy Vulnerability Debuff, reducing Energy Resistance by -[1130, 1200] for 7.5 second(s).

Symbiote Supreme: Each time Stagger expires without nullifying a Buff, Symbiote Supreme gains 15 Genetic Potential.
Unique Synergy: Does not stack with duplicate synergies.
Shathra
Wasp
Yellow Jacket
The True Queen of the Hive
Shathra: Power Steal is replaced with a Power Gain, granting 160% of a Bar of Power per second.

Wasp: If the Opponent throws a Special Attack while Wasp’s personal Power Sting is active it will trigger Wasp’s Petrify. However, the Petrify when this occurs is capped at 200% potency.

Yellow Jacket: When the Opponent activates a Special Attack while personal Power Stings are active, gain 8 Nuclear Core Charges for each Power Sting removed.
Unique Synergy: Does not stack with duplicate synergies.
Vox
Thor
Thor (Jane Foster)
THE VILLAIN’S WEAKNESS
Vox: Attacking and Defending Vox: While fighting against Synergy Champions, receive +10% damage from hits involving hammers.
Other Synergy Champions: Attacks involving hammers have +10% Attack Rating.
Unique Synergy: Does not stack with duplicate synergies.
Lumatrix
Isophyne
The Virtue of Duty
Lumatrix: While Invisible, Lumatrix’s fourth Light Attack grants them their personal Unblockable Passive for 2 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Shang Chi
Spider-Man (Classic)
THE WAY OF THE SPIDER
Shang Chi: Critical Hits bypass +20% of Armor and Resistances.

Spider-Man (Classic): Spider-Man can use Perfect-Timing while performing a Well-Timed Block or Dodging an attack to inflict a Physical Vulnerability Debuff reducing the Opponent’s Physical Resistance by 1400 for 30 seconds. Max 3 stack(s).
Unique Synergy: Does not stack with duplicate synergies.
Absorbing Man
Thor (Jane Foster)
Thor
THE WORTHY
Absorbing Man: The second Medium Attack inflicts an Armor Break Debuff, reducing Armor by 500 for 9 seconds. Max stacks: 5

Thor (Jane Foster): When facing Cosmic champions, The Mighty Thor inflicts Degeneration effects instead of personal Shocks, which count as Shocks for her abilities.

Thor: Thor’s Heavy attack inflicts an Armor Break Debuff, reducing Armor by 1800 for 4.5 seconds. Max stacks: 2
Unique Synergy: Does not stack with duplicate synergies.
Falcon (Joaquin Torres)
Captain America (Sam Wilson)
Falcon
There goes my hero!
Falcon (Joaquin Torres): For each Velocity Charge gained throughout the fight, gain +1% Attack Rating and +50 Block Proficiency. Max: 50 Velocity Charges.

Captain America (Sam Wilson): Reduce Recon Scan’s cooldown by [25%].

Falcon: Reduce Recon Scan’s cooldown by [25%].
Unique Synergy: Does not stack with duplicate synergies.
Psycho-Man
Deadpool (X-Force)
Deadpool
Man-Thing
THERE GOES THE MULTIVERSE
Psycho-Man: Power Lock and Heal Block effects last 15% longer.

Deadpool (X-Force): Heavy Attacks inflict a non-stacking Armor Break Debuff, reducing Armor Rating by -700 for 10 second(s). Reverberate this!

Deadpool: Heavy Attacks inflict a non-stacking Armor Break Debuff, reducing Armor Rating by -700 for 10 second(s). Reverberate this!

Man-Thing: Gain up to 25% Perfect Block Chance based on Agitation.
Unique Synergy: Does not stack with duplicate synergies.
Man-Thing
Thing
THINGS
Man-Thing: Well Timed Blocks grant a Fury Buff increasing its Attack by 25% of its Base Attack for 1.5 seconds. This Fury doesn’t stack.

Thing: Thing’s Rock Stacks last Indefinitely up to 20.
Unique Synergy: Does not stack with duplicate synergies.
Spider-Punk
Green Goblin
Red Goblin
Iron Patriot
This ain’t MAX pal!!
Spider-Punk: Personal Rupture Debuffs expire 10% slower. This becomes 20% slower against #Symbiotes.

Green Goblin: Whenever a Bag of Tricks effect fails due to chance, gain a Tricky Passive, increasing the Ability Accuracy of Bag of Tricks effects by 5% flat for 18 seconds. Max: 5. Tricky Passives have no effect on Super Bombs.

Red Goblin: When the Opponent’s Miss or Auto-block fails due to a reason other than chance while True Sense is active, gain a +30% Fury Buff for 10 seconds. Max: 2.

Iron Patriot: Personal Armor Break Debuffs have their Ability Accuracy increased by a flat amount to a total of 100%.
Unique Synergy: Does not stack with duplicate synergies.
Bastion
Sentinel
Nimrod
Omega Sentinel
This is my Family
Bastion: Personal Disintegration effects gain 20% increased duration.

Sentinel: While the Opponent is suffering from a personal Shock effect, ERADICATE Protocol expires 30% slower.

Nimrod: At max Analysis Charges, personal non-Damaging Debuffs expire 50% slower during the Opponent’s Special Attacks.

Omega Sentinel: Personal non-Damaging Debuff durations are increased by +2.5 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Mantis
Psycho-Man
THIS ONE ALSO HAS MIXED EMOTIONS!
Mantis: Whenever Mantis inflicts a Mixed Emotion Passive, there is a 25% chance to inflict another.

Psycho-Man: Whenever Psychoman cycles his Control Box Mode, he gains 20% of a bar of Power over 1 second.
Unique Synergy: Does not stack with duplicate synergies.
Mantis
Gamora
Star-Lord
THIS ONE CAN SENSE THAT IT'S COMPLICATED
Mantis: The duration of personal Infuriate and Intimidate Debuffs are increased by 2 seconds.

Gamora: While Gamora has at least 6 personal Buffs active, her Special 2 becomes Unblockable.

Star-Lord: Elemental Guns are no longer random, effects can be cycled by double tapping Block. Effects are cycled: Fire, Air, Water, Earth.
Unique Synergy: Does not stack with duplicate synergies.
Mantis
Dormammu
Loki
Thanos
THIS ONE HAS ENEMIES
All Champions gain +[85, 115, 155] Critical Rating
Mantis
Silver Surfer
Vision
THIS ONE HAS FOUND ROMANCE
All Champions gain +[3, 4, 5]% Combat Power Rate.