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Silver Centurion
Captain America
Captain America (Infinity War)
Captain America (WWII)
PATRIOT GARRISON
Captain America: Each time the Opponent is immune to a Stun effect, gain an Unstoppable Buff for 1 second.

Captain America (Infinity War): Each time the Opponent is immune to a Stun effect, gain an Unstoppable Buff for 1 second.

Captain America (WWII): Each time the Opponent is immune to a Stun effect, gain an Unstoppable Buff for 1 second.
Unique Synergy: Does not stack with duplicate synergies.
Hercules
Hawkeye
PAWN SET FREE
Hercules: Infuriate cooldown is reduced by 20%.

Hawkeye: Draining the Opponent’s Power across a Power Bar threshold grants a Fury Buff increasing Attack Rating by 20% for 20 seconds. Max stacks 3.
Unique Synergy: Does not stack with duplicate synergies.
Count Nefaria
Doctor Strange
Iron Fist
Mister Sinister
Gladiator
Peak Fashion
Synergy Champions: Block Proficiency increased by +400.
Unique Synergy: Does not stack with duplicate synergies.
Yelena Belova
Hawkeye
Bullseye
Longshot
Perfectly Placed Shots
Synergy Champions: Bleed effects that are inflicted during a non-contact attack gain 25% potency, excludes Special Attack 3.
Unique Synergy: Does not stack with duplicate synergies.
The Champion
Mephisto
Sentry
PERSISTENT FORCE
The Champion: When The Champion has 3 or more Persistent Charges, he starts the fight with an Indestructible Buff, ignoring all incoming damage for 8 seconds.

Mephisto: +15% Attack Rating for each Persistent Charge.

Sentry: 3% increased Personal Debuff duration for each Reality Warp.
Unique Synergy: Does not stack with duplicate Synergies.
Silver Centurion
Mole Man
Squirrel Girl
PET PALS
Silver Centurion: f the Opponent is suffering less than 5 stacks of Plasma, Special Attack 2 inflicts one extra Plasma.

Mole Man: Gain 20% Attack Rating during Special Attack 1.

Squirrel Girl: Gain 20% Attack Rating during Special Attack 1.
Unique Synergy: Does not stack with duplicate synergies.
Jubilee
Gambit
Rogue
PETITE
Jubilee: +20% Prowess Potency.

Gambit: At the start of each fight gain 2 Kinetic Charges.

Rogue: +5% Attack Rating for each Unique Buff.
Unique Synergy: Does not stack with duplicate synergies.
Nova
Drax
Gambit
PHALANX FEUD
Nova: Increase the potency of Fury Buffs by 15%.

Drax: When performing a Dash Attack, 30% chance to gain an Aptitude Buff increasing the Potency of Fury Buffs by 15% for 12 seconds.

Gambit: When performing a Dash Attack, 30% chance to gain an Aptitude Buff increasing the Potency of Fury Buffs by 15% for 12 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Emma Frost
Phoenix
PHOENIX FORCE
Emma Frost: Whenever Emma would gain one Prowess Passive, she gains two instead.

Phoenix: When the Stun from Cosmic Flame Aura fails due to Immunity, gain 10 Phoenix Force Charges.
Unique Synergy: Does not stack with duplicate synergies.
The Destroyer
Peni Parker
Howard The Duck
Piloted
The Destroyer: Gain 2250 Energy Resistance.

Peni Parker: Gain 25% Power Burn potency.

Howard The Duck: When the Opponent Purifies a Stun Debuff, or is Immune to it, gain 1 personal Fury Buff.
Unique Synergy: Does not stack with duplicate synergies.
Korg
Thor (Ragnarok)
PIT FIGHTERS
Korg: +15% Attack Rating and +20% Fury Buff for 8 seconds when using a Medium Attack to end a Basic Attack Combo while their opponent is pinned against the wall.

Thor (Ragnarok): +15% Attack Rating and +20% Fury Buff for 8 seconds when using a Medium Attack to end a Basic Attack Combo while their opponent is pinned against the wall.
Unique Synergy: Does not stack with duplicate Synergies.
Bullseye
Cyclops (New Xavier School)
Cyclops (Blue Team)
Pitcher Perfect
Bullseye: If an attack doesn’t Critically Hit a non-Mutant Opponent, gain a non-stacking 50% Fury Buff for 3 seconds. This Buff will not re-trigger while already active, and is not affected by Ability Accuracy reduction.

Cyclops (New Xavier School): Intercepting the Opponent with a Beam Attack grants a non-stacking 50% Fury Buff for 3 seconds.

Cyclops (Blue Team): Intercepting the Opponent with a Beam Attack grants a non-stacking 50% Fury Buff for 3 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Bastion
Peni Parker
Players of the Game
Bastion: Special Attack Infection abilities trigger even if Infection is not active. This can only trigger 2 times per match.

Peni Parker: Special 3 sets the Sync-Shield’s strength to 200%.
Unique Synergy: Does not stack with duplicate synergies.
Masacre
Red Hulk
PLAYING WITH FIRE
Masacre: Blocking a contact attack while Ignited places an Incinerate on the Opponent as if they had been Struck by Masacre’s bat.

Red Hulk: Start the fight with 2 Heat Charges.
Unique Synergy: Does not stack with duplicate synergies.
The Serpent
Vox
Terrax
Galan
Jabari Panther
Mister Negative
Polearm Pals
Synergy Champions: Striking the Opponent while their back is against the wall grants a 500 potency Cruelty Buff for 6 seconds. This does not reapply if active.
Unique Synergy: Does not stack with duplicate synergies.
Purgatory
Guillotine
POOR, UNFORTUNATE SOUL
Purgatory: At the start of Purgatory’s first fight in a quest, gain the Mystic Cross-Fight Class Soul.

Guillotine: Bleeds triggered by Critical Hits have a chance to be Critical Bleeds, depending on Critical chance. Critical Bleeds multiply their damage by Guillotine’s Critical Damage multiplier.
Unique Synergy: Does not stack with duplicate synergies.
Jessica Jones
Luke Cage
POWER COUPLE
Jessica Jones: Increased chance of throwing the Box with Special Attack 1. Also, start each fight with an Indestructible Charge from Jessica’s Special Attack 3.

Luke Cage: Ability Accuracy for personal Exhaustions inflicted by Light Attacks is increased by 15% flat.
Unique Synergy: Does not stack with duplicate synergies.
Nick Fury
Loki
Scarlet Witch (Classic)
POWER KIT
All Champions except Nick: If Nick is alive, once per fight when a teammate is inflicted with an effect that would reduce or block their Power Bar he will drop a Power Kit, Removing the effect and granting 1 bar of power over 10 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Yellow Jacket
Joe Fixit
Kingpin
Taskmaster
Yondu
POWER OF MONEY
Yellow Jacket: Inflicting a Debuff grants +10 Core Charge. Cooldown: 10 seconds.
Villain Champions: +5% Attack Rating.
Unique Synergy: Does not stack with duplicate Synergies.
Karolina Dean
Angela
Shuri
Powerful Princesses
Karolina Dean: Karolina’s Special 3 cannot be activated unless charging a Heavy Attack.

Angela: Special Attacks inflict at least 4 Armor Breaks regardless of Buff quantity and personal Armor Breaks last 30% longer.

Shuri: Special 1 hits grant an additional Matrix Charge.
Unique Synergy: Does not stack with duplicate synergies.