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Magneto (House of X)
Colossus
Guardian
REDEMPTION
Magneto (House of X): Defeating #Villain Champions grants 1 Persistent Charge. +10% Attack while fighting #Villains.

Colossus: Opponent’s Nullify & Stagger effects suffer -65% Ability Accuracy.

Guardian: Gain Force Field charges 3.5 seconds faster.
Unique Synergy: Does not stack with duplicate Synergies.
Black Widow (Deadly Origin)
Taskmaster
REMEMBER ME
Black Widow (Deadly Origin): Each time Black Widow strikes with Widow’s Insight active she gains 2% of a Bar of Power.

Taskmaster: Each time he Exploits a Weakness, Taskmaster has a 30% chance to Inflict a Sabotage Debuff, reducing Defensive Ability Accuracy by 20% for 10 seconds and dealing 10% of Attack as direct Damage when Abilities fail to trigger.
Unique Synergy: Does not stack with duplicate synergies.
Black Widow (Deadly Origin)
Hawkeye
Ronin
REMEMBERING BUDAPEST
Black Widow (Deadly Origin): Reduce the potency of incoming Bleed Debuffs by 10%. Reduce the potency by an additional 10% if either Ronin or Hawkeye is Dead.

Hawkeye: Increase the duration of Bleed and Disorient Debuffs by 10%. Gain an additional 30% Duration if Black Widow (Deadly Origin) is Dead.

Ronin: Increase the duration of Bleed and Disorient Debuffs by 10%. Gain an additional 30% Duration if Black Widow (Deadly Origin) is Dead.
Unique Synergy: Does not stack with duplicate synergies.
Nimrod
Omega Sentinel
Sentinel
RESISTANCE IS FUTILE
Nimrod: Up to +25% Armor Rating based on missing Health.
Robots: If a Robot is defeated. They gain a Self-Repair Cross-Fight which gets consumed when they enter their next Fight, Regenerating 25% of their missing health over 20 seconds. This effect ends early if Stunned.
Unique Synergy: Does not stack with duplicate Synergies.
Wong
Shang Chi
RESPONSIBLE ADULTS
Wong: Special Attack 1 grants an additional 10 Eldritch Energy.

Shang Chi: Special Attack 3 Readys all Unreadied Wushu Strikes and triggers Guaranteed Crits for 8 second(s).
Unique Synergy: Does not stack with duplicate synergies.
Nick Fury
Deadpool (X-Force)
Deadpool
Platinum Pool
RESTORATION KIT
All Champions except Nick: If Nick is alive, once per fight when a teammate is inflicted with a Bleed, Poison or Shock Debuff he will drop a Restoration Kit, Purifying the Debuff and Regenerating 10% of their max health over 3 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Kindred
Mephisto
REVENANT BIRTH
Kindred: Activating Dread Aura grants an Unblockable Passive for 3 seconds. Cooldown: 20 seconds.
Solo Synergy: Only affects this Champion and does not stack.
Negasonic Teenage Warhead
Doctor Strange
Human Torch
Moon Knight
Phoenix
Revivified Support Group
Negasonic Teenage Warhead: While below 5% Health, the chance to Evade Medium and Light Attacks with Precognition becomes 100% until an Evade activates.
Synergy Champions: +10% Health.
Unique Synergy: Does not stack with duplicate synergies.
Yellow Jacket
Killmonger
Magneto
Mole Man
Storm (Pyramid X)
REVOLUTIONS NEED ARMS
Yellow Jacket: Nuclear Core Starting Charge and Overheat Point are increased by +10.
Villain Champions: +5% Health Rating.
Unique Synergy: Does not stack with duplicate Synergies.
Magneto (House of X)
Apocalypse
Professor X
RISE AGAINST THE CONTEST
Magneto (House of X): +5% Attack rating during the fight and Magneto’s Atonement Synergy gains +25% Potency.

Apocalypse: Horsemen gain +30% Prowess Potency.

Professor X: All of Professor X's Prowess Buffs gain 20% Duration.
Unique Synergy: Does not stack with duplicate Synergies.
Shuri
Misty Knight
RIVAL METALLURGY
Synergy Members: Shock and Coldsnap effects gain +20% potency and are paused during the Opponent’s Special Attacks.
Unique Synergy: Does not stack with duplicate synergies.
Warlock
Ultron (Classic)
Ultron
Vision
Vision (Age of Ultron)
ROBOT UPRISING
Whenever any teammate would receive a Debuff they are immune to, they gain a Fury Buff, increasing Attack Rating by 60% for 6 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Absorbing Man
Titania
ROGUE'S ROMANCE
Absorbing Man: Medium and Heavy Attacks gain 600 Critical Damage Rating.

Titania: Gain Immunity to Bleed effects.
Unique Synergy: Does not stack with duplicate synergies.
Domino
Colossus
Wolverine
ROMANCE
All Teammates gain +[3, 4, 5]% Power Gain.
Mojo
ROMANCE - MOJO
Mojo: Gain +5% Power Gain.
Solo: Mojo only loves himself.
Unique Synergy: Does not stack with duplicate synergies.
Dust
Wolverine (X 23)
Roommates
Dust: Striking an Unstoppable Opponent while Sandstorm is active grants Dust a personal Prowess Passive.

Wolverine (X 23): Start each fight with a Disguised Charge. When struck by an attack that would deal more than 5% of Wolverine’s Max Health, consume the Charge to lower the damage to 0. This ability does not work against Special Attack 3.
Unique Synergy: Does not stack with duplicate synergies.
Spot
Mysterio
ROOMMATES
Spot: Gain 10% Rupture Debuff Potency.

Mysterio: Gain 1 Chemical Gas when a hit Misses Mysterio. 10 second cooldown.
Unique Synergy: Does not stack with duplicate synergies.
Iron Man (Infamous)
Mephisto
ROTTED SOULS
Iron Man (Infamous): Whenever Infamous Iron Man is immune to an effect, he deals the Opponent a burst of Energy Damage equal to 200% of his Attack Rating. Each subsequent time this ability triggers, its potency is reduced by 20%.

Mephisto: Duration of Soul imprisonment is doubled.
Unique Synergy: Does not stack with duplicate synergies.
Black Panther
Storm
ROYALS
Black Panther: Gain a 1 second Unblockable Passive when activating a Special Attack during Panther’s Might.

Storm: Each Shock Debuff on the opponent grants +20% Special Attack Damage, Max Potency at 5 Shocks.
Unique Synergy: Does not stack with duplicate synergies.
Daredevil (Hell's Kitchen)
Daredevil (Classic)
Ronan
She-Hulk
RULE OF LAW
Daredevil (Hell's Kitchen): Special Attacks have a 20% chance to inflict a Stun Debuff. Duration is 1.25 seconds per level of Special Attack used.
Synergy Champions: +10% Attack Rating.
Unique Synergy: Does not stack with duplicate Synergies.