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PAST AND PRESENT SELF

Captain Britain
Psylocke
Captain BritainStriking an Opponent with a Critical Hit inflicts a non-stacking Degeneration Debuff dealing 50% Attack Rating as Direct Damage over 6 seconds.

PsylockeStriking an Opponent with a Critical Hit inflicts a non-stacking Degeneration Debuff dealing 50% Attack Rating as Direct Damage over 6 seconds.

Unique Synergy: Does not stack with duplicate synergies.

PASSIVE AGGRESSIVE

Thing
Human Torch
ThingWhen Thing is at 20 Rock Stacks, any additional stacks he would gain are immediately converted into Passive Fury effects.

Unique Synergy: Does not stack with duplicate synergies.

PARTYGOERS

Sersi
Hercules
SersiSpecial Hits that break through an Opponent’s Block with an Unblockable Buff become Guaranteed Critical Hits.

HerculesFeat of Strength: Gain 1 Indefinite Strength for every 10 hits in the Combo Meter.

Unique Synergy: Does not stack with duplicate synergies.

PARTNERS IN S.H.I.E.L.D

Captain Marvel
Nick Fury
Captain MarvelEach Energy Charge lasts an additional 1 second while in Binary Ignition.

Nick FuryEach Tactical Advantage charge lasts an additional 1 second.

Unique Synergy: Does not stack with duplicate synergies.

PARTICLE PHYSICS

Doctor Octopus
Electro
Doctor OctopusWhen a Breakthrough expires, Research Categories reset to 50.

ElectroGains 50% additional Power from Critical Hits.

Unique Synergy: Does not stack with duplicate synergies.

PACT WITH A DEMON

Mephisto
Doctor Strange
Ghost Rider
MephistoGain 70% increased Incinerate potency.

Doctor StrangeGain 10% increased Regeneration potency.

Ghost RiderGain +10% Attack Rating.

Unique Synergy: Does not stack with duplicate synergies.

OVERCOMING FEAR

Void
Black Widow
Captain America
Hawkeye
Vision
VoidFear of the Void activates at the start of the fight for 30 seconds against the Avengers.

Avengers: +15% Attack Rating.
Unique Synergy: Does not stack with duplicate synergies.

OUT OF THIS WORLD

America Chavez
Ghost Rider
The Hood
America ChavezDark Dimension Regenerates 30% of damage dealt to the Opponent by this Dimension.

Dimensional Beings: +25% resistance to Degeneration Damage.
Unique Synergy: Does not stack with duplicate Synergies.

OUR SHARED CURSE

Guillotine 2099
Guillotine
Morningstar
Guillotine 2099+30% Degeneration Potency.

Guillotine+20% Personal Bleed Ability Accuracy and Duration.

Morningstar+300 Critical Damage per Captured Soul.

Unique Synergy: Does not stack with duplicate synergies.

OTHERWORLDLY TESTIMONY

Galan
Mister Fantastic
GalanAll Incinerate Debuff durations are increased by 50%.

Mister FantasticWhenever a Personal Debuff expires on the Opponent, gain 20% of a bar of Power.

Unique Synergy: Does not stack with duplicate synergies.

OTHER HALF

Sentry
Void
SentryAfter a Special Attack 3, Sentry inflicts a Fear of the Void Passive. Fear of the Void combines a 60% Agility, 35% Fatigue, and 100% Petrify’s effects for 20 seconds.

Unique Synergy: Does not stack with duplicate synergies.

OSBORN TO BE WILD

Iron Patriot
Red Goblin
Iron PatriotArc Overload grants a Fury Buff increasing Attack Rating by 300% for 30 seconds, no longer burns out Iron Patriot’s Suit, and can be reactivated after a 60 second cooldown.

Red GoblinWhile Frenzy is active, Fury and Energize Buffs have 15% increased Potency.

Unique Synergy: Does not stack with duplicate Synergies.

ONE WAY OR ANOTHER

Invisible Woman
Emma Frost
Magik
Omega Red
Sabretooth
Sentry

Passive Fury, Prowess, Regeneration, Indestructible, and Limbo effects last 10% longer.
Unique Synergy: Does not stack with duplicate synergies.

ON YOUR LEFT

Captain America (Sam Wilson)
Captain America (Infinity War)
Captain America (WWII)
Captain America (Sam Wilson)On Well-Timed Blocks gain a Fury Buff, increasing Attack Rating by 13%. Fury has no duration but it is removed when hit or on a non Well-Timed Block. Max 5 stacks.

Captain America (Infinity War)On a Well-Timed Block, inflict a Stagger Debuff that lasts for 10 second(s). The Staggered Opponent has their next Buff Nullified. Max 2 Stacks.

Captain America (WWII)On a Well-Timed Block, inflict a Stagger Debuff that lasts for 10 second(s). The Staggered Opponent has their next Buff Nullified. Max 2 Stacks.

Unique Synergy: Does not stack with duplicate synergies.

OLD TEAMMATES

Havok
Wolverine
Nightcrawler
HavokEach time Havok deals Energy Damage to the Opponent he has a 10% Chance to gain 1 Plasma Charge.

WolverinePassively increases Attack by 20% of Base Attack while under the effect of a Regeneration Buff.

NightcrawlerBegin the fight in Swashbuckling Mode, and while in this mode his chance to Instant Bleed is increased by a flat 30%.

Unique Synergy: Does not stack with duplicate synergies.

ON GUARD FOR THEE

Guardian
Deadpool
Sabretooth
Squirrel Girl
Wolverine

All Champions except Guardian: The first 3 blocks have a 100% chance to be Perfect Blocks.
Unique Synergy: Does not stack with duplicate synergies.

OIL IS THICKER THAN BLOOD

Omega Sentinel
Sentinel
Omega SentinelIncinerate and Plasma Debuffs inflicted by Medium combo enders instantly Power Drain the Opponent for 5% of their Max Power.

SentinelKnocking down an Opponent removes 1 Prowess effect from them.

Unique Synergy: Does not stack with duplicate synergies.

OFF LIMITS

Hela
Hulk (Ragnarok)
HelaHela begins the fight with 1 Fury Buff, and if she is ever without a Fury Buff for 10 seconds, she gains one.

Hulk (Ragnarok)Hulk's chance to SMASH on Attacks increases by 400% while Face Me is active.

Unique Synergy: Does not stack with duplicate synergies.

OBSESSION

Kraven
Spider-Man (Classic)
Spider-Man (Symbiote)
KravenOnce per Fight when receiving damage that would result in a knockout, gain an Immortality Buff preventing death for 8 second(s).

Spider-Man (Classic)8+ Webbing: Root Debuff lasting 2 seconds.

Spider-Man (Symbiote)Armor Break Debuffs are paused during Specials and their duration is increased by 7 second(s).

Unique Synergy: Does not stack with duplicate synergies.

OATHSWORN

Odin
Heimdall
OdinOnce per fight Heimdall will intercede on Odin's behalf, dash back and hold Block for 1.5 seconds to gain a Perfect Block Buff, increasing Perfect Block chance by 100% for 10 second(s).

HeimdallHeimdall’s indefinite Fury, Armor Up, Precision and Aptitude Buffs gained from charging a Heavy Attack gain +15% potency.

Unique Synergy: Does not stack with duplicate synergies.