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Domino
Masacre
MERCS FOR MONEY
Domino: Debuffs last 1 second(s) longer.

Masacre: At the start of the fight, and when Ignited expires, gain between 1 and 5 Ignition Charges.
Unique Synergy: Does not stack with duplicate synergies.
Colossus
Omega Red
Wolverine
METAL MAYHEM
Colossus: +2% Attack Rating for each Armor Up Buff and Well Timed Blocks grant an Armor Buff.[Max 1 Stack]

Omega Red: +4% Critical Damage for each Death Spore on the opponent.

Wolverine: +20% Stronger Bleeds and +5% Critical Rating.
Cable
Magneto (House of X)
Taskmaster
Wolverine (X 23)
METALIC AFFINITY
Cable: Begin the fight with 60% Poison Resistance.

Magneto (House of X): Gain an indefinite Prowess Buff, granting +20% Special attack damage.

Taskmaster: Exploit Weakness attacks deal +40% Damage.

Wolverine (X 23): Bleed & Cruelty effects gain +35% duration.
Unique Synergy: Does not stack with duplicate Synergies.
Ghost
Wasp
MICROSCOPIC OBSERVATION
Ghost: Special Attacks are Unblockable when triggered while Phasing.
Unique Synergy: Does not stack with duplicate synergies.
Okoye
Shuri
Midnight Angels
Okoye: If Awakened, gain 15% increased Debuff duration. Otherwise, gain Level 1 of Okoye’s Signature Ability.

Shuri: Shock Debuffs gain 25% increased duration.
Unique Synergy: Does not stack with duplicate synergies.
Night Thrasher
Punisher
Moon Knight
MIDNIGHT PURSUIT
Night Thrasher: Medium Attacks have a 30% chance to inflict Bleed, dealing 50% of Base Attack as Direct Damage over 3 seconds. As the Moon waxes, the chance to Bleed on Medium Attacks is 100%.

Punisher: The duration of Bleeds are increased 40%.

Moon Knight: The duration of Bleeds are increased 40%.
Unique Synergy: Does not stack with duplicate synergies.
Mysterio
Night Thrasher
MINE CAN HOVER
Mysterio: When dashing forward Mysterio has 70% chance to inflict the Opponent with Falter for the duration of the dash. Opponents suffering Falter have a 100% chance to Miss their attacks.
Solo: Only affects this Champion and does not stack.
Mysterio
Night Thrasher
Silver Surfer
MINE TRAVELS THROUGH SPACE
Mysterio: Mysterio’s advantages against Spider-Verse champions extends to all Hero Champions.

Night Thrasher: Board attacks deal a burst of 5% bonus Physical Damage for each Unique Debuff on the Opponent.

Silver Surfer: Board attacks generate 30% less Power for the Opponent.
Unique Synergy: Does not stack with duplicate Synergies.
The Serpent
The Destroyer
Odin
Minister of Justice
Synergy Champions: While the Opponent is below 25% Max Health, gain a 20% Flourish Passive.
Unique Synergy: Does not stack with duplicate synergies.
Ebony Maw
Stryfe
MISS ME?
Ebony Maw: Gain +15% Attack Rating while the Opponent is suffering from a Falter Debuff.

Stryfe: Once per fight after being struck by a Basic Attack the Opponent is inflicted with a Passive Falter for 3 seconds giving them a 100% chance to Miss.
Unique Synergy: Does not stack with duplicate synergies.
Agent Venom
Kraven
Venompool
MISUNDERSTANDING
Agent Venom: On Critical Hits or when the Opponent fails to Evade inflict a Bleed Debuff, dealing 50% of Attack in Direct Damage over 4 second(s).

Kraven: Kraven’s True Accuracy also ignores the effects of Miss.

Venompool: When fighting Bleed immune Champions, when inflicting Bleeds, inflict a matching Degeneration instead.
Unique Synergy: Does not stack with duplicate synergies.
King Groot
Man-Thing
MISUNDERSTOOD MONSTERS
King Groot: Malice grants 2 additional Fury Buffs.

Man-Thing: Well Timed Blocks inflict a Poison Debuff dealing 25% of its Attack as damage over 5 seconds, and reducing Regeneration effects by 30%.
Unique Synergy: Does not stack with duplicate synergies.
Longshot
Mojo
MOJOVERSE
Longshot: f the Opponent is Immune to Bleed, Longshot's Special 1 inflicts Degen Damage instead.

Mojo: 50% chance to not lose Followers when failing a Prompt.
Unique Synergy: Does not stack with duplicate synergies.
Thanos (Deathless)
King Groot (Deathless)
Molten Fist
King Groot (Deathless): Malice’s bonus to Fury potency can continue to build to a maximum of 200% after 200 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Photon
Mister Negative
Monochrome
Photon: Reduce the potency of incoming Degeneration effects by 20% for each unique personal Debuff on the Opponent.

Mister Negative: When activating his personal Evade, inflict a non-stacking Slow Debuff for [5] seconds. Cooldown: 8 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Abomination
Man-Thing
Mole Man
MONSTER MASH
Abomination: When inflicted with a Debuff, gain a Fury Buff increasing Attack by 50% for 12 seconds.

Man-Thing: Heavy Attacks are guaranteed Critical Hits while Man-Thing is Unstoppable.

Mole Man: Increases the duration of Monster Mass while Frenzied by 10%.
Unique Synergy: Does not stack with duplicate synergies.
Hawkeye
Taskmaster
MOSTLY AVERAGE JOES
Hawkeye: Each Successful Release triggered since the last time the Special 3 was activated increases duration of Bleeds by an additional 20%.

Taskmaster: If Taskmaster’s Current Exploit Weakness target attack is a Special Attack, all his Special Attacks become Unblockable.
Unique Synergy: Does not stack with duplicate synergies.
Storm
Apocalypse
MPENDING STORM
Storm: Each hit of a Heavy Attack into a Shocked Opponent has a 60% chance to inflict an additional Shock Debuff, dealing 70% of modified attack over 8 seconds.
If this champion is a Horseman of Apocalypse Shock effects last +50% longer and Heavy Attacks refresh all Shock Debuffs on the Opponent.
Unique Synergy: Does not stack with duplicate synergies.
Spiral
Rogue
Gambit
Mr. and Mrs. X
Spiral: Gain Immunity to Reversed Controls.

Rogue: The Opponent starts the fight with an indefinite +1500 Precision Buff.

Gambit: While a Precision is active, gain +800 Block Proficiency.
Unique Synergy: Does not stack with duplicate synergies.
Black Cat
Ghost
Titania
MS. CREANTS
Black Cat: When the Heist ends, pause Black Cat’s currently active Cruelty Passives for 7 seconds.

Ghost: Gain +300 Armor Rating.

Titania: Gain +20% more Power from Heavy Attacks.
Unique Synergy: Does not stack with duplicate synergies.