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White Tiger
Gladiator
Mano A Mano
White Tiger: Power Steal has a 49.5% chance of not going on cooldown.

Gladiator: Charging a Heavy Attack while the Opponent’s back is against the wall grants a Fury Buff increasing Attack Rating by +50.5% for 2 seconds, paused during Gladiator’s Special Attacks. Max stacks: 3.
Unique Synergy: Does not stack with duplicate synergies.
Hulk (Immortal)
Purgatory
MANY AS ONE
Hulk (Immortal): Triggering Immortality consumes 5% less Max Health as Gamma Radiation.

Purgatory: 20% chance per Captured Class Soul to instantly Regenerate 20% Health just before being Knocked Out, once per fight.
Unique Synergy: Does not stack with duplicate synergies.
Captain Marvel (Classic)
Ms. Marvel
Captain Marvel
MARVELOUS
Captain Marvel (Classic): While Fury is active, Beam Attacks are Unblockable.

Ms. Marvel: While Fury is active, Beam Attacks are Unblockable.

Captain Marvel: Blocking energy-based attacks grants 2% of Max Power.
Unique Synergy: Does not stack with duplicate synergies.
Gentle
Mole Man
Galan
Massive Gains
Gentle: Gain +57 Block Rating per Muscle Mass.

Mole Man: When activating Frenzy, gain a True Accuracy Buff for 2 seconds per Monster Mass, to a max of 14 seconds.

Galan: Reaching 315 Planetary Mass while the Harvest is not active grants a Heavy Attack Stun Charge. While this Charge is active, starting a Heavy Charge while the Opponent is within striking Distance inflicts a Stun Passive for 0.6 seconds and consumes the Charge.
Unique Synergy: Does not stack with duplicate synergies.
Shang Chi
Iron Fist
Iron Fist (Immortal)
MASTER MARTIAL ARTISTS
Shang Chi: Start the fight with 4 Chi Charge(s).

Iron Fist: Each hit in all Special Attacks are Guaranteed Critical Hits and gain a flat +35% personal Armor Break Ability Accuracy.

Iron Fist (Immortal): Each hit in all Special Attacks are Guaranteed Critical Hits and gain a flat +35% personal Armor Break Ability Accuracy.
Unique Synergy: Does not stack with duplicate synergies.
Black Panther
Hercules
MASTERFUL COMBAT
Black Panther: Dashing back during a Basic Attack combo inflicts a non-stacking Infuriate Debuff for 5 seconds, making the Opponent more aggressive and reducing their Offensive Ability Accuracy by 30%. Cooldown 10 seconds.

Hercules: On activation of Special Attack 1 or 2, gain an Unblockable Buff for 3 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Moon Knight
Ronin
MASTERLESS
Moon Knight: 30% chance to instantly Regenerate 35% of damage taken when struck.

Ronin: Gain a Fury Buff increasing Attack Rating by 15% for 4 seconds upon switching Stances.
Unique Synergy: Does not stack with duplicate synergies.
Loki
Magneto
Magneto (House of X)
MASTERMINDS
All Champions gain +[17, 20]% Energy Damage once a Combo of 15 or more hits is reached.
Mister Sinister
M.O.D.O.K.
Kingpin
Ultron
MASTERMINDS
Mister Sinister: Each time the opponent uses a Special Attack they become Power Locked for 6 seconds.

M.O.D.O.K.: Each time the opponent uses a Special Attack they become Power Locked for 6 seconds.

Kingpin: Each time the opponent uses a Special Attack they become Power Locked for 6 seconds.

Ultron: Each time the opponent uses a Special Attack they become Power Locked for 6 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Guillotine
Morningstar
MASTERS OF THE SWORD
Guillotine: Temporary Soul Charges last 10 seconds longer.

Morningstar: At the start of the fight, if she has less than 2 Captured Souls, she gains 1.
Unique Synergy: Does not stack with duplicate synergies.
Bishop
Havok
Nova
MAXIMUM OUTPUT
Bishop: Receiving Energy Damage generates 1 additional stack of Prowess.

Havok: 10% chance to place a new Plasma Build Up Debuff on the Opponent when it is Removed or Purified.

Nova: Gain 1 Nova Charge each time Nova receives Energy Damage.
Unique Synergy: Does not stack with duplicate synergies.
Captain America (Infinity War)
Iron Man (Infinity War)
QuickSilver
Thor (Ragnarok)
MAYBE AVENGER
Captain America (Infinity War): Increase the potency of Fury effects by 25%.

Iron Man (Infinity War): While the Opponent is suffering from Armor Break, they are also inflicted with a Passive Cowardice, reducing Special Damage by 40%.

QuickSilver: Increase Block Proficiency by [1000, 1250].

Thor (Ragnarok): 75% chance to Purify any non-Damaging Debuff.
Unique Synergy: Does not stack with duplicate synergies.
Agent Venom
Anti-Venom
MAYBE LATER
Agent Venom: Gain 10% Power anytime a Debuff is purified.

Anti-Venom: Inflicting a Genetic Memory Debuff deals a burst of 40% of Modified Attack in Physical Damage.
Unique Synergy: Does not stack with duplicate synergies.
Rocket Raccoon
Dragon Man
Gamora
Groot
Star-Lord
ME AND THESE IDIOTS ARE GONNA OBLITERATE YOU!
#Guardian Champions: Gain +7% Attack Rating.
Emma Frost
Sentinel
MEMORIES OF GENOSHA
Emma Frost: +15% Attack Rating in Diamond Form.

Sentinel: +4 Physical Resistance for each Analysis Charge.
Unique Synergy: Does not stack with duplicate synergies.
Mysterio
Emma Frost
MENTAL IMMUNITY
Mysterio: Grants immunity to reverse controls.

Emma Frost: Grants immunity to reverse controls.
Unique Synergy: Does not stack with duplicate synergies.
Jean Grey
Professor X
Mentor
Jean Grey: Personal Delirium effects gain a flat +20% potency.

Professor X: His personal Falter can trigger against Special Attacks while charging a Heavy Attack. When it does, the cooldown is increased by 15 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Platinum Pool
Rogue
MERC WITH A MOUTH
Platinum Pool: Platinumpool: Increase the chance to draw the Blood Drive Card.
Solo: Only affects this Champion and does not stack.
Crossbones
Hit-Monkey
Nebula
Platinum Pool
Yondu
MERCENARY COMPETITION
Crossbones: [Contempt] is expanded to include any Non-Villain Champion.
Mercenary & Villain Champions: +5% Attack Rating & +400 Critical Damage Rating.
Unique Synergy: Does not stack with duplicate synergies.
Yelena Belova
Silver Sable
Hit-Monkey
Absorbing Man
Deadpool (X-Force)
Mercenary Competition
Yelena Belova: Personal Impact and Disarm effects start paused for 6 seconds.
#Mercenary & #Villain Champions: +5% Attack Rating and +400 Critical Damage Rating.
Unique Synergy: Does not stack with duplicate synergies.