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Diablo
Juggernaut
Kraven
Mephisto
LEGION ACCURSED
Diablo: Poison effects on the opponent reduce healing effects by 50% each instead of 30%.

Juggernaut: While Unstoppable, Juggernaut doubles his Armor Rating.

Kraven: Traps deal an additional +40% Direct Damage.

Mephisto: Gain 50% of a bar of Power when a Poison Debuff would be gained. Cooldown: 10 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Morbius
Carnage
Venom
Misty Knight
Iron Fist
Lethal Protectors
All Champions gain +85 Critical Rating.
Unique Synergy: Does not stack with duplicate synergies.
Ebony Maw
Corvus Glaive
Cull Obsidian
Proxima Midnight
LIEUTENANTS OF THE BLACK ORDER
All Members of Thanos Army: When the fight starts, gain a True Damage Buff allowing Attacks to bypass Armor and Resistances for 30 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Storm
Toad
LIGHTNING ROD
Storm: Deal 15% of Attack as a burst of instant Shock damage while the Opponent is suffering from a Stun Debuff.

Toad: Special Attacks have +15% Crit Rating while Paralytic Secretion is active.
Unique Synergy: Does not stack with duplicate synergies.
Dani Moonstar
Phoenix
Professor X
Emma Frost
Psylocke
LIKE A BOOK
Synergy Champions: Well-Timed Blocks grant a non-stacking 20% Energy Resistance Passive for 10 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Loki
Thor (Ragnarok)
LIKE OLD DAYS
Loki: Ascendant Signature Ability is enhanced to provide Power Gain while below 2 bars of Power.

Thor (Ragnarok): When struck for the first time each fight, 100% chance to gain a Combo Shield Passive lasting 10 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Mangog
Purgatory
Rhino
Rintrah
LIVE AND DIE BY THE HORNS
Mangog: Gain a 10% Attack Rating per Stagger on Opponent.

Purgatory: Class Souls last an extra 2 Fight(s).

Rhino: Gain a 25% Crit Rating when Unstoppable.

Rintrah: 30% chance to reapply any Ruptures removed on Special 2.
Unique Synergy: Does not stack with duplicate synergies.
Guillotine
Nightcrawler
Ronin
LIVE AND DIE BY THE SWORD
Guillotine: Reaching a Combo Meter increment of 25 grants 1 Soul Charge.

Nightcrawler: When switching Combat Modes, gain +350 Critical Damage Rating for 10 seconds.

Ronin: Blocking Attacks has a 50% chance to inflict a Bleed Debuff causing 25% of Attack Rating as direct damage over 5 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Colossus
Unstoppable Colossus
Red Guardian
LIVING STEEL CURTAIN
Colossus: Activating any Special Attack has a 50% chance to trigger a Unstoppable Buff, lingering 1.2 seconds after the Attack ends.

Unstoppable Colossus: Personal Fury Buffs gain an additional flat +10% chance to trigger and last 200% longer. Additionally landing a Heavy Attack pauses all personal Fury Buffs until another is gained.
Unique Synergy: Does not stack with duplicate synergies.
Black Bolt
Cyclops (New Xavier School)
Ikaris
LORDS OF ENERGY
Black Bolt: Gains an Energize Buff granting +100% Combat Power Rate for 4 seconds, when a Personal Stun Debuff is applied.

Cyclops (New Xavier School): Gains +25% Fury when inflicting a Armor Break Debuff for 10 seconds. Max Stack of 4.

Ikaris: Gains 1 bonus stacks of Incinerate on Special 1 when paired with Cyclops or Black Bolt (stacks if with both).
Unique Synergy: Does not stack with duplicate synergies.
Heimdall
Angela
Hela
LOST DAUGHTERS OF ASGARD
All Champions except Heimdall: Once per fight Heimdall will intercede on your behalf, dash back and hold Block for 1.5 seconds to gain an infinite Duration Fury Buff increasing Attack by 15% of Base Attack.
Unique Synergy: Does not stack with duplicate synergies.
Thor (Jane Foster)
Gorr
Korg
Thor (Ragnarok)
Valkyrie
LOVE & THUNDER
Synergy Champions: +5% Combat Power Rate, +130 Armor Rating, +5% Perfect Block Chance & +6% Attack Rating.
Unique Synergy: Does not stack with duplicate synergies.
Nico Minoru
Karolina Dean
Love Brighter than the Sun
Nico Minoru: New Pre-Fight spell: Siphon – When the Opponent finishes a Special Attack, Nico Power Steals 80% of their remaining Power over 2 seconds and gains 50% of the Power Stolen.
Unique Synergy: Does not stack with duplicate synergies.
Karolina Dean
Nico Minoru
Love to the Moon and back
Karolina Dean: When a personal Incinerate fails due to Immunity against Tech Champions, inflict a Plasma Passive instead, copying personal Incinerate behavior. Additionally, personal Incinerates and Plasmas have their potency increased by 15%.
Unique Synergy: Does not stack with duplicate synergies.
Longshot
Rogue
Love Triangles:
Longshot: Longshot's Special 2 has a 42% chance to inflict an additional Incinerate for each Bad Karma removed by Fate Seal.

Rogue: Whenever stealing a Buff Rogue deals 20% of her Base Attack as Degeneration damage for each Buff stolen.
All Female Champions: Gain 200 Critical Rating and 12% increased Ability Accuracy.
Unique Synergy: Does not stack with duplicate Synergies.
Captain America
Captain America (WWII)
Captain America (Infinity War)
Punisher 2099
LOYAL MINISTER
Captain America: Clean hits gain +20% Attack rating if the opponent has a Stun, Bleed or Fatigue Debuff.

Captain America (WWII): Clean hits gain +20% Attack rating if the opponent has a Stun, Bleed or Fatigue Debuff.

Captain America (Infinity War): Clean hits gain +20% Attack rating if the opponent has a Stun, Bleed or Fatigue Debuff.

Punisher 2099: Begin the fight with 25% additional Battery charge.
Unique Synergy: Does not stack with duplicate synergies.
Black Widow
Hulk (Ragnarok)
LULLABY
Black Widow: Evade chance increases by 100%.

Hulk (Ragnarok): When Struck Hulk has a 20% chance to ready a SMASH for his next attack.
Unique Synergy: Does not stack with duplicate synergies.
Diablo
Doctor Octopus
Green Goblin
M.O.D.O.K.
MADCAP EXPERIMENTALISTS
Diablo: Special Attacks have a 70% chance to inflict a Stun Debuff, lasting 1.5 second(s) per level of Special Attack used.

Doctor Octopus: +35% Heal Block Debuff duration.

Green Goblin: +1.5% Attack Rating per Cunning / Madness Charge.

M.O.D.O.K.: +20% personal Debuff Duration.
Unique Synergy: Does not stack with duplicate synergies.
Red Guardian
Sabretooth
MAGNIFICENT MANES
Red Guardian: While the Ablative Shield is Fractured, gain an indefinite Passive Fury, granting +10% Attack Rating until the Shield is repaired.

Sabretooth: Potency of Fury effects are increased by 10%.
Unique Synergy: Does not stack with duplicate synergies.
Invisible Woman
Psycho-Man
MALICE
Invisible Woman: While Invisible, Attacks have a 25% chance to place a Fragility Debuff on the Opponent.

Psycho-Man: Psycho-Man’s Ability Accuracy reduction effects reduce Ability Accuracy by an additional -15% flat.
Unique Synergy: Does not stack with duplicate synergies.