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Captain America (Infinity War)
Iron Man (Infinity War)
QuickSilver
Thor (Ragnarok)
MAYBE AVENGER
Captain America (Infinity War): Increase the potency of Fury effects by 25%.

Iron Man (Infinity War): While the Opponent is suffering from Armor Break, they are also inflicted with a Passive Cowardice, reducing Special Damage by 40%.

QuickSilver: Increase Block Proficiency by [1000, 1250].

Thor (Ragnarok): 75% chance to Purify any non-Damaging Debuff.
Unique Synergy: Does not stack with duplicate synergies.
Agent Venom
Anti-Venom
MAYBE LATER
Agent Venom: Gain 10% Power anytime a Debuff is purified.

Anti-Venom: Inflicting a Genetic Memory Debuff deals a burst of 40% of Modified Attack in Physical Damage.
Unique Synergy: Does not stack with duplicate synergies.
Rocket Raccoon
Dragon Man
Gamora
Groot
Star-Lord
ME AND THESE IDIOTS ARE GONNA OBLITERATE YOU!
#Guardian Champions: Gain +7% Attack Rating.
Emma Frost
Sentinel
MEMORIES OF GENOSHA
Emma Frost: +15% Attack Rating in Diamond Form.

Sentinel: +4 Physical Resistance for each Analysis Charge.
Unique Synergy: Does not stack with duplicate synergies.
Mysterio
Emma Frost
MENTAL IMMUNITY
Mysterio: Grants immunity to reverse controls.

Emma Frost: Grants immunity to reverse controls.
Unique Synergy: Does not stack with duplicate synergies.
Platinum Pool
Rogue
MERC WITH A MOUTH
Platinum Pool: Platinumpool: Increase the chance to draw the Blood Drive Card.
Solo: Only affects this Champion and does not stack.
Crossbones
Hit-Monkey
Nebula
Platinum Pool
Yondu
MERCENARY COMPETITION
Crossbones: [Contempt] is expanded to include any Non-Villain Champion.
Mercenary & Villain Champions: +5% Attack Rating & +400 Critical Damage Rating.
Unique Synergy: Does not stack with duplicate synergies.
Domino
Masacre
MERCS FOR MONEY
Domino: Debuffs last 1 second(s) longer.

Masacre: At the start of the fight, and when Ignited expires, gain between 1 and 5 Ignition Charges.
Unique Synergy: Does not stack with duplicate synergies.
Colossus
Omega Red
Wolverine
METAL MAYHEM
Colossus: +2% Attack Rating for each Armor Up Buff and Well Timed Blocks grant an Armor Buff.[Max 1 Stack]

Omega Red: +4% Critical Damage for each Death Spore on the opponent.

Wolverine: +20% Stronger Bleeds and +5% Critical Rating.
Cable
Magneto (House of X)
Taskmaster
Wolverine (X 23)
METALIC AFFINITY
Cable: Begin the fight with 60% Poison Resistance.

Magneto (House of X): Gain an indefinite Prowess Buff, granting +20% Special attack damage.

Taskmaster: Exploit Weakness attacks deal +40% Damage.

Wolverine (X 23): Bleed & Cruelty effects gain +35% duration.
Unique Synergy: Does not stack with duplicate Synergies.
Ghost
Wasp
MICROSCOPIC OBSERVATION
Ghost: Special Attacks are Unblockable when triggered while Phasing.
Unique Synergy: Does not stack with duplicate synergies.
Night Thrasher
Punisher
Moon Knight
MIDNIGHT PURSUIT
Night Thrasher: Medium Attacks have a 30% chance to inflict Bleed, dealing 50% of Base Attack as Direct Damage over 3 seconds. As the Moon waxes, the chance to Bleed on Medium Attacks is 100%.

Punisher: The duration of Bleeds are increased 40%.

Moon Knight: The duration of Bleeds are increased 40%.
Unique Synergy: Does not stack with duplicate synergies.
Mysterio
Night Thrasher
MINE CAN HOVER
Mysterio: When dashing forward Mysterio has 70% chance to inflict the Opponent with Falter for the duration of the dash. Opponents suffering Falter have a 100% chance to Miss their attacks.
Solo: Only affects this Champion and does not stack.
Mysterio
Night Thrasher
Silver Surfer
MINE TRAVELS THROUGH SPACE
Mysterio: Mysterio’s advantages against Spider-Verse champions extends to all Hero Champions.

Night Thrasher: Board attacks deal a burst of 5% bonus Physical Damage for each Unique Debuff on the Opponent.

Silver Surfer: Board attacks generate 30% less Power for the Opponent.
Unique Synergy: Does not stack with duplicate Synergies.
The Serpent
The Destroyer
Odin
Minister of Justice
Synergy Champions: While the Opponent is below 25% Max Health, gain a 20% Flourish Passive.
Unique Synergy: Does not stack with duplicate synergies.
Ebony Maw
Stryfe
MISS ME?
Ebony Maw: Gain +15% Attack Rating while the Opponent is suffering from a Falter Debuff.

Stryfe: Once per fight after being struck by a Basic Attack the Opponent is inflicted with a Passive Falter for 3 seconds giving them a 100% chance to Miss.
Unique Synergy: Does not stack with duplicate synergies.
Agent Venom
Kraven
Venompool
MISUNDERSTANDING
Agent Venom: On Critical Hits or when the Opponent fails to Evade inflict a Bleed Debuff, dealing 50% of Attack in Direct Damage over 4 second(s).

Kraven: Kraven’s True Accuracy also ignores the effects of Miss.

Venompool: When fighting Bleed immune Champions, when inflicting Bleeds, inflict a matching Degeneration instead.
Unique Synergy: Does not stack with duplicate synergies.
King Groot
Man-Thing
MISUNDERSTOOD MONSTERS
King Groot: Malice grants 2 additional Fury Buffs.

Man-Thing: Well Timed Blocks inflict a Poison Debuff dealing 25% of its Attack as damage over 5 seconds, and reducing Regeneration effects by 30%.
Unique Synergy: Does not stack with duplicate synergies.
Longshot
Mojo
MOJOVERSE
Longshot: f the Opponent is Immune to Bleed, Longshot's Special 1 inflicts Degen Damage instead.

Mojo: 50% chance to not lose Followers when failing a Prompt.
Unique Synergy: Does not stack with duplicate synergies.
Photon
Mister Negative
Monochrome
Photon: Reduce the potency of incoming Degeneration effects by 20% for each unique personal Debuff on the Opponent.

Mister Negative: When activating his personal Evade, inflict a non-stacking Slow Debuff for [5] seconds. Cooldown: 8 seconds.
Unique Synergy: Does not stack with duplicate synergies.