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Black Panther
Killmonger
KINGS
Black Panther: Intercepting the Opponent grants a True Strike Passive for 10 seconds, letting his attack ignore all Armor, Resistances, Evade, and Auto-Block effects.

Killmonger: Can activate Special 3 Bleed Debuffs an additional 1 time per fight.
Unique Synergy: Does not stack with duplicate synergies.
Namor
Black Panther
King Groot
Kingpin
KINGS OF THE WORLD
All Champions: Each member of this Synergy increases the teams Special Attack damage by +12% for as long as they are alive (max 36%).
Unique Synergy: Does not stack with duplicate synergies.
Misty Knight
Captain America (Sam Wilson)
Iron Fist
Iron Fist (Immortal)
KNIGHTS IN SHINING ARMOR
All Champions gain +[15, 35, 60] Armor Rating & 3% Power Gain
Iron Man
Hulkbuster
Spider Man (Stark Enhanced)
KNOWLEDGE SHARE
Iron Man: +30% Special Damage.

Hulkbuster: +30% Special Damage.

Spider Man (Stark Enhanced): A.I. Reboots 30% faster.
Unique Synergy: Does not stack with duplicate synergies.
Knull
KNULLIFICATION
All #Symbiotes except Knull: Once per fight Knull possesses his Symbiote teammate when they would be knocked out, gaining an Indestructible and Fury Buff granting +50% Attack Rating for 10 second(s). When the Indestructible Buff expires, deal 5% of Max Health as Direct Damage to the teammate.
All Champions except Knull: Gain +2% Attack Rating for each of Knull’s active Synergy Bonuses. #Symbiotes gain double.
Unique Synergy: Does not stack with duplicate synergies.
Hulkling
Squirrel Girl
KOOKIE TRIPLET
Hulkling: 50% chance when Striking the Opponent while Unblockable to inflict a non-stacking Armor Break Debuff for 10 second(s), reducing Armor Rating by 500.

Squirrel Girl: 25% chance to Purify one of each Non-Damaging Debuff each time the Opponent is inflicted by a Bleed Debuff.
Unique Synergy: Does not stack with duplicate synergies.
Wolverine (Weapon X)
Sabretooth
LAB PARTNERS
Wolverine (Weapon X): +15% Bleed Debuff Potency.

Sabretooth: +15% Bleed Debuff Potency.
Unique Synergy: Does not stack with duplicate synergies.
Adam Warlock
Mister Negative
Green Goblin
Anti-Venom
LAB RATS
Adam Warlock: +10% Fury Buff potency.

Mister Negative: +10% Fury Buff potency.

Green Goblin: +10% Attack Rating during Special Attack 2.

Anti-Venom: +10% Attack Rating during Special Attack 2.
Unique Synergy: Does not stack with duplicate synergies.
Captain Marvel
Ronin
LAST HOPE
Captain Marvel: Intercepting attacks have +150 Critical Rating.

Ronin: The duration of Bleed Debuffs is increased 3% for each active Cruelty.
Unique Synergy: Does not stack with duplicate synergies.
Sunspot
Captain America
Iron Man (Infinity War)
Iron Man
LEADING AVENGERS
Avengers and New Avengers: When fighting Villain Champions, reduce the Potency of any Power Sting and damage over time effects by 10%. Increased to up to 40% based on Sunspot's Signature Level.
Unique Synergy: Does not stack with duplicate Synergies.
Havok
Sauron
LEECHING THY FRIEND
Havok: Upon consuming 1 Power Bar, gain an 20% Prowess Passive for 6 seconds.

Sauron: Upon gaining 1 Power Bar, gain a 20% Armor Up Passive for 6 seconds.
Unique Synergy: Does not stack with duplicate synergies.
She-Hulk
Daredevil (Classic)
Daredevil (Hell's Kitchen)
LEGAL DEFENSE
She-Hulk: +15% duration for personal Fury Passive effects.

Daredevil (Classic): +800 Critical Rating during Special Attacks.

Daredevil (Hell's Kitchen): +800 Critical Rating during Special Attacks.
All Champions gain +15% Stun Ability Accuracy.
Unique Synergy: Does not stack with duplicate synergies.
Diablo
Juggernaut
Kraven
Mephisto
LEGION ACCURSED
Diablo: Poison effects on the opponent reduce healing effects by 50% each instead of 30%.

Juggernaut: While Unstoppable, Juggernaut doubles his Armor Rating.

Kraven: Traps deal an additional +40% Direct Damage.

Mephisto: Gain 50% of a bar of Power when a Poison Debuff would be gained. Cooldown: 10 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Morbius
Carnage
Venom
Misty Knight
Iron Fist
Lethal Protectors
All Champions gain +85 Critical Rating.
Unique Synergy: Does not stack with duplicate synergies.
Ebony Maw
Corvus Glaive
Cull Obsidian
Proxima Midnight
LIEUTENANTS OF THE BLACK ORDER
All Members of Thanos Army: When the fight starts, gain a True Damage Buff allowing Attacks to bypass Armor and Resistances for 30 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Storm
Toad
LIGHTNING ROD
Storm: Deal 15% of Attack as a burst of instant Shock damage while the Opponent is suffering from a Stun Debuff.

Toad: Special Attacks have +15% Crit Rating while Paralytic Secretion is active.
Unique Synergy: Does not stack with duplicate synergies.
Dani Moonstar
Phoenix
Professor X
Emma Frost
Psylocke
LIKE A BOOK
Synergy Champions: Well-Timed Blocks grant a non-stacking 20% Energy Resistance Passive for 10 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Loki
Thor (Ragnarok)
LIKE OLD DAYS
Loki: Ascendant Signature Ability is enhanced to provide Power Gain while below 2 bars of Power.

Thor (Ragnarok): When struck for the first time each fight, 100% chance to gain a Combo Shield Passive lasting 10 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Mangog
Purgatory
Rhino
Rintrah
LIVE AND DIE BY THE HORNS
Mangog: Gain a 10% Attack Rating per Stagger on Opponent.

Purgatory: Class Souls last an extra 2 Fight(s).

Rhino: Gain a 25% Crit Rating when Unstoppable.

Rintrah: 30% chance to reapply any Ruptures removed on Special 2.
Unique Synergy: Does not stack with duplicate synergies.
Guillotine
Nightcrawler
Ronin
LIVE AND DIE BY THE SWORD
Guillotine: Reaching a Combo Meter increment of 25 grants 1 Soul Charge.

Nightcrawler: When switching Combat Modes, gain +350 Critical Damage Rating for 10 seconds.

Ronin: Blocking Attacks has a 50% chance to inflict a Bleed Debuff causing 25% of Attack Rating as direct damage over 5 seconds.
Unique Synergy: Does not stack with duplicate synergies.