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TOXIC LOVE

Toad
Scarlet Witch (Classic)
Scarlet Witch (Sigil)
Toad+15% Combat Power Rate while Paralytic Secretion is active.

Solo Synergy: Only affects this Champion and does not stack.

TOUGH BRAWLERS

The Champion
Luke Cage
The ChampionThe Champion is Unstoppable when using a Light and Medium Attack.

Luke Cage+35% chance to inflict Debuffs as long as Luke Cage never dashes back in a fight.

Unique Synergy: Does not stack with duplicate Synergies.

TOTAL ANNIHILATION

Nova
Annihilus
NovaGain +40% Perfect Block chance when triggering Auto-Block.

Annihilus+65% Physical Resistance while Unstoppable.

Unique Synergy: Does not stack with duplicate synergies.

TOO MANY SORCERERS...

Mordo
Doctor Voodoo
Sorcerer Supreme
Wong
MordoWhile fighting Mystic Champions, Mordo is Immune to Nullify and Fate Seal.

Synergy Champions: +6% Attack Rating.
Unique Synergy: Does not stack with duplicate synergies.

TIME TRAVELERS

Anti-Venom
Doctor Octopus
Spider Man 2099
Anti-VenomFor the first 10 second(s) of the fight the Opponent is immune to Buffs.

Doctor OctopusWhen dealing damage per Breakthrough removed on a Heavy Attack, 25% chance per Breakthrough to inflict another burst of damage dealing Attack Rating in damage.

Spider Man 2099On the start of the fight, inflict a Wither Debuff on the Opponent with a potency of 125% for 15 second(s).

Unique Synergy: Does not stack with duplicate synergies.

Till Infinity Do Us Part:

Scarlet Witch (Sigil)
Vision
Vision (Age of Ultron)
Scarlet Witch (Sigil)When Chaos Surge activates, 8% chance to gain an Aptitude Buff increasing Fury, Precision, and Armor Up Buffs by 30% for 18 seconds.

VisionLanding a Heavy Attack on an Opponent suffering Heal Block grants a non-stacking Fury, increasing Attack Rating by 1000 for 15 seconds.

Vision (Age of Ultron)Landing a Heavy Attack on an Opponent suffering Heal Block grants a non-stacking Fury, increasing Attack Rating by 1000 for 15 seconds.

Unique Synergy: Does not stack with duplicate Synergies.

TIDE TO GO

Namor
Moon Knight
NamorUnder a Full or New Moon, attacking or being attacked by Bleeding Opponents grants 5% of a bar of Power with each Strike. As the Moon waxes and wanes, Attack Rating is increased by +15%.

Moon KnightUnder a Full or New Moon, Combat Power Rate is increased by 10%. As the Moon waxes and wanes, Bleed and Fury potency is increased by 15%.

Unique Synergy: Does not stack with duplicate synergies.

THUNDERBOLTS

Luke Cage
Red Hulk
Agent Venom
Elektra
Iron Patriot
Juggernaut

All Champions take [5, 10, 15]% less Special Damage

THUNDERBOLTS

Taskmaster
Winter Soldier
TaskmasterCurrent Exploit Weakness target Attack has a 20% chance to become Unblockable.

Winter SoldierWintersoldier’s EMP Upgrade gains a flat +5% chance to trigger.

Unique Synergy: Does not stack with duplicate synergies.

THROUGH THICK AND THIN

Kitty Pryde
Emma Frost
Kitty PrydeBecome Immune to reverse controls, and each time this immunity is triggered gain +1 personal Prowess. Cooldown 0.8 seconds.

Emma FrostGain +20% Attack Rating in diamond form and gain +20% Combat Power Rate in telepathic form.

Unique Synergy: Does not stack with duplicate synergies.

THIS ONE WON'T LET ANYTHING GO OVER YOUR HEAD!

Mantis
Drax
MantisMantis' Sleep inflicted by charging Heavy Attack has its duration increased by 0.5 seconds flat.

DraxDrax can now Parry non-contact hits.

Unique Synergy: Does not stack with duplicate synergies.

THIS ONE THINKS VIOLENCE IS NOT THE SOLUTION

Mantis
Rocket Raccoon
MantisWhile at least 1 personal Cruelty Buff is active, gain a Precision Passive, increasing Critical Rating by 350.

Rocket RaccoonInflicting Power Drains with Special 1 now consumes 12 Scrap Metal instead of 15.

Unique Synergy: Does not stack with duplicate synergies.

THIS ONE HAS FOUND ROMANCE

Mantis
Silver Surfer
Vision

All Champions gain +[3, 4, 5]% Combat Power Rate.

THIS ONE HAS ENEMIES

Mantis
Dormammu
Loki
Thanos

All Champions gain +[85, 115, 155] Critical Rating

THIS ONE CAN SENSE THAT IT'S COMPLICATED

Mantis
Gamora
Star-Lord
MantisThe duration of personal Infuriate and Intimidate Debuffs are increased by 2 seconds.

GamoraWhile Gamora has at least 6 personal Buffs active, her Special 2 becomes Unblockable.

Star-LordElemental Guns are no longer random, effects can be cycled by double tapping Block. Effects are cycled: Fire, Air, Water, Earth.

Unique Synergy: Does not stack with duplicate synergies.

THIS ONE ALSO HAS MIXED EMOTIONS!

Mantis
Psycho-Man
MantisWhenever Mantis inflicts a Mixed Emotion Passive, there is a 25% chance to inflict another.

Psycho-ManWhenever Psychoman cycles his Control Box Mode, he gains 20% of a bar of Power over 1 second.

Unique Synergy: Does not stack with duplicate synergies.

THINGS

Man-Thing
Thing
Man-ThingWell Timed Blocks grant a Fury Buff increasing its Attack by 25% of its Base Attack for 1.5 seconds. This Fury doesn’t stack.

ThingThing’s Rock Stacks last Indefinitely up to 20.

Unique Synergy: Does not stack with duplicate synergies.

THERE GOES THE MULTIVERSE

Psycho-Man
Deadpool (X-Force)
Deadpool
Man-Thing
Psycho-ManPower Lock and Heal Block effects last 15% longer.

Deadpool (X-Force)Heavy Attacks inflict a non-stacking Armor Break Debuff, reducing Armor Rating by -700 for 10 second(s). Reverberate this!

DeadpoolHeavy Attacks inflict a non-stacking Armor Break Debuff, reducing Armor Rating by -700 for 10 second(s). Reverberate this!

Man-ThingGain up to 25% Perfect Block Chance based on Agitation.

Unique Synergy: Does not stack with duplicate synergies.

THE WAY OF THE SPIDER

Shang Chi
Spider-Man (Classic)
Shang ChiCritical Hits bypass +20% of Armor and Resistances.

Spider-Man (Classic)Spider-Man can use Perfect-Timing while performing a Well-Timed Block or Dodging an attack to inflict a Physical Vulnerability Debuff reducing the Opponent’s Physical Resistance by 1400 for 30 seconds. Max 3 stack(s).

Unique Synergy: Does not stack with duplicate synergies.

THE SUPREMES

Spider-Man (Supreme)
Sorcerer Supreme
Symbiote Supreme
Spider-Man (Supreme)Granting Spider-Seal Buffs to an Opponent that has no Buff or only Spider-Seal Buffs, inflicts a burst of 10% of Attack as Energy Damage.

Sorcerer SupremeSpecial Attacks inflict an Energy Vulnerability Debuff, reducing Energy Resistance by -[1130, 1200] for 7.5 second(s).

Symbiote SupremeEach time Stagger expires without nullifying a Buff, Symbiote Supreme gains 15 Genetic Potential.

Unique Synergy: Does not stack with duplicate synergies.