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Masacre
Valkyrie
Hulkling
CHIP OUT THE OLD BLOCK
Masacre: The final hit of Masacre’s Heavy Attack inflicts an Intimidate Debuff for 10 second(s), making the Opponent more defensive and reducing their Block Proficiency by 20%. This ability can’t be activated again until the next time Masacre’s bat ignites.

Valkyrie: Increase the potency of Pierce effects by 10%.

Hulkling: Increase the potency of Pierce effects by 10%.
Unique Synergy: Does not stack with duplicate synergies.
Bishop
Psylocke
CHRONAL ANCHOR
Bishop: Opponents are inflicted with a Petrify of 100% Potency for 1 second after they fill a bar of Power. This Petrify is paused during Bishop's Special Attacks.

Psylocke: Opponents are inflicted with a Petrify of 100% Potency for 1 second after they fill a bar of Power. This Petrify is paused during Psylocke’s Special Attacks.
Unique Synergy: Does not stack with duplicate synergies.
Captain America (Infinity War)
Captain America
Longshot
CIVIL WAR STORIES
Captain America (Infinity War): Start a Fight with 1 Kinetic Potential when fighting Avengers or New Avengers.

Captain America: While the Opponent is Fatigued their Ability Power Rate is reduced by 110%.

Longshot: Start a Fight with 5 Good Karma when fighting Villain Champions.
Unique Synergy: Does not stack with duplicate Synergies.
Arcade
Kraven
Black Cat
Wolverine
Claws
Arcade: Successful Auto-Blocks grant a +80% Fury Buff for 3 seconds, paused during Arcade’s Special Attacks.

Kraven: Gain Bleed Immunity. Personal Bleeds last 50% longer, but lose 33% potency.

Black Cat: Start each fight with a 3 second Combo Shield Passive. This starts paused and is unpaused when Black Cat Evades or is struck while no other Combo Shields are active.

Wolverine: For each personal Bleed on the Opponent, they suffer -20% Evade Ability Accuracy.
Unique Synergy: Does not stack with duplicate synergies.
Cable
Stryfe
CLONED AT BIRTH
Cable: While the Opponent is suffering from a Degeneration effect Special Attacks grant 50% less power in the Opponent.

Stryfe: Start the fight with +5 Telepathic Charges.
Unique Synergy: Does not stack with duplicate synergies.
Onslaught
Cable
Stryfe
Close Enough
Onslaught: Striking an Opponent or their Block while they are Unstoppable consumes 3 personal Daunted effects and removes the Unstoppable. Cooldown: 20 seconds.
Solo Synergy: Only affects this Champion and does not stack.
Anti-Venom
Venom
Carnage
CLOSE FAMILY
Anti-Venom: #Symbiote Opponents have the Ability Accuracy of their Buffs reduced by 50%.

Venom: Regenerates 15% of max Health when knocking out #Spider-Verse Heroes.

Carnage: Regenerates 15% of max Health when knocking out #Spider-Verse Heroes.
Unique Synergy: Does not stack with duplicate synergies.
Longshot
Psylocke
Sabretooth
Spider Man 2099
CO-WORKERS
Longshot: When Longshot Nullifies a Regeneration Buff, gain a Regeneration Buff, healing 5% of base health over 10 second(s).

Psylocke: Attacking an Opponent with 0 Power reduces their Defensive Ability Accuracy by 50%.

Sabretooth: Blocking an attack has a 10% chance to grant a Regeneration Passive that heals 25% of the damage taken from the block over 25 second(s).

Spider Man 2099: Spider-Man 2099 gains 85 Critical Rating per Unique Debuff on the Opponent.
Unique Synergy: Does not stack with duplicate synergies.
Domino
Red Hulk
CODE RED REVELATIONS
Domino: Heavy Attacks inflict an Incinerate that deals damage equal to that Heavy Attack’s damage over 2 second(s).

Red Hulk: Special 2 Regeneration consumes 1 less Heat Charge and recovers 18% more Health.
Unique Synergy: Does not stack with duplicate synergies.
Count Nefaria
Baron Zemo
The Hood
Colleagues in Crime
Count Nefaria: At the start of each fight, activate Ionic Overcharge for 50% of its normal duration. No Ionic Charges are lost the first time Ionic Overcharge expires.

Baron Zemo: Light Hits pause Zemo’s Root for 0.2 seconds.

The Hood: Once per fight when the Hood has 0 Bullets, he loads 12 Bullets.
Unique Synergy: Does not stack with duplicate synergies.
Doctor Doom
Mister Fantastic
COLLEGE RIVALS
Doctor Doom: Heavy Attacks apply up to 1 Armor Break Debuff for 10 second(s), reducing Armor Rating by 15%.

Mister Fantastic: Gain 5% of his Max Power each time a Buff is Nullified or its Duration expires off the Opponent.
Unique Synergy: Does not stack with duplicate synergies.
Ægon
Proxima Midnight
Star-Lord
COMBO BREAKERS
Ægon: Activates Combo Shield for 5 seconds when this Champion would lose their Combo Meter. This ability activates only 1 time per fight.

Proxima Midnight: Activates Combo Shield for 5 seconds when this Champion would lose their Combo Meter. This ability activates only 1 time per fight.

Star-Lord: Activates Combo Shield for 5 seconds when this Champion would lose their Combo Meter. This ability activates only 1 time per fight.
Unique Synergy: Does not stack with duplicate synergies.
The Champion
Thor (Ragnarok)
COMBO FIGHTER
The Champion: Gains a Persistent Charge for every 20 hits in his Combo Meter.

Thor (Ragnarok): +0.8% Attack Rating per hit in the Combo Meter. Max: 100 hits.
Unique Synergy: Does not stack with duplicate Synergies.
Hulkbuster
Sasquatch
COMMON HISTORY
Hulkbuster: Start the fight with an indefinite Armor Up Buff, granting +15% Armor Rating. This can stack above Hulkbusters Armor Up cap.

Sasquatch: Each stack of Rage increases Wrath of Tanaraq by an additional 0.3 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Joe Fixit
Kingpin
The Hood
COMPETITION
Joe Fixit: Unique Dead Man’s Hand Debuffs provide +10% Debuff Duration.

Kingpin: +100% Rage Purify Ability Accuracy.

The Hood: +25% Invisibility Duration.
Unique Synergy: Does not stack with duplicate synergies.
Kindred
Green Goblin
Iron Patriot
Red Goblin
COMPOUND MADNESS
Kindred: When Nightmare Outbreak activates, gain an Unstoppable Buff for 7 seconds.

Green Goblin: +10% Combat Power Rate while under 1 Bar of Power.

Iron Patriot: 30% chance when gaining an Armor Up Buff to inflict a 10% Physical Vulnerability Debuff for 12 seconds. Max stacks: 3.

Red Goblin: When charging a Heavy Attack, gain a 20% Energize Buff for 5 seconds. Cooldown: 7.5 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Dust
Ms. Marvel (Kamala Khan)
Connected Faith
Dust: After spinning up a Sandstorm, Dust’s next Special Attack is Passively Unblockable.

Ms. Marvel (Kamala Khan): When Kamala’s Poison Immunity is triggered, she gains a Fury Buff, increasing her Attack Rating by +15% for 5 seconds. Max stacks: 3.
Unique Synergy: Does not stack with duplicate synergies.
Gorr
Knull
CONSUMING DARKNESS
Gorr: Heavy Hits grant a non-stacking Vicious Buff for 10 second(s), increasing the potency of Damage over Time effects by 20%.

Knull: While the Opponent is Corrupted, Necrosword Attacks inflict an additional instant Bleed dealing 30% of Attack Rating in Damage.
Unique Synergy: Does not stack with duplicate synergies.
Crossbones
Mangog
CONTEMPTUOUS HATRED
Crossbones: [Contempt] Fury Buffs gain +50% Duration.

Mangog: Start the fight with +1 Hatred while fighting #Hero Champions.
Unique Synergy: Does not stack with duplicate synergies.
Crossbones
King Groot
CONTEMPTUOUS MALICE
Crossbones: [Contempt] Start the fight with 2 Fury Buff(s).

King Groot: While fighting #Hero Champions, Malice grants an additional Fury Buff and the chance to gain Fury Charges during Cooldown is increased by a flat +10%.
Unique Synergy: Does not stack with duplicate synergies.