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Gamora
Nebula
SIBLING RIVALRY
Gamora: Robot opponents suffer -10% Ability Accuracy and -2% Attack Rating for each personal Buff on Gamora.

Nebula: The first Special 1 each fight is a guaranteed Critical Hit. The same is true for the first Special 2.
All Synergy Champions: +5% Attack Rating.
Unique Synergy: Does not stack with duplicate synergies.
Cassie Lang
QuickSilver
America Chavez
Viv Vision
SICK KICKS
Synergy Champions: All attacks involving shoes have their Attack Rating increased by 5%.
Scream
Carnage
Anti-Venom
Silence and Misery
Scream: For each unique personal Debuff on the Opponent, they suffer -10% Defensive Combat Power Rate.

Carnage: For each unique personal Debuff on the Opponent, they suffer -10% Defensive Combat Power Rate.

Anti-Venom: Accelerated Mutation Passives and Evolved Mutation Passives gain 20% duration.
Unique Synergy: Does not stack with duplicate synergies.
M.O.D.O.K.
Ultron (Classic)
Ultron
SINGULARITY
M.O.D.O.K.: Guaranteed Critical Hit occurs in 5 hits instead of 7.

Ultron (Classic): +200 Critical Damage Rating & +10% Perfect Block Chance.

Ultron: Triggering Function (Critical) also triggers Function (Damage).
Unique Synergy: Does not stack with duplicate synergies.
Kindred
Mysterio
Vulture
Scorpion
Doctor Octopus
Kraven
SINISTER MANIPULATOR
Synergy Members: +15% Attack Rating against #Spider-Verse Heroes.
Kraven
Doctor Octopus
Electro
Green Goblin
Rhino
Vulture
SINISTER SIX
Synergy Champions: When fighting #Heroes Combat Power Rate is increased by 25%.
Unique Synergy: Does not stack with duplicate synergies.
Sandman
Iron Patriot
Mysterio
Red Goblin
Scorpion
Shocker
SINISTER SUBSTITUTES
Synergy Champions: When fighting #Heroes Combat Power Rate is increased by 10%.
Unique Synergy: Does not stack with duplicate synergies.
Absorbing Man
Daredevil (Hell's Kitchen)
SINS OF THE FATHER
Absorbing Man: While at or below 15 Combo Meter, gain 1000 Block Proficiency, and while above, gain 1000 Critical Rating.

Daredevil (Hell's Kitchen): Personal Buffs last for an additional 7 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Jean Grey
Storm
Sisters
Jean Grey: The first hit of Jean’s Heavy Attack pauses her personal Daunted for 5 seconds.

Storm: Activating a Striker or Special Attack while charging or releasing a Heavy Attack pauses all Prowess effects on Storm for 10 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Enchantress
Lady Deathstrike
Psylocke
Sisters in Hood
Enchantress: New Evocation Spell: Poison Spray: ↓ , ↓ , ↑. Inflicts three Poison Debuffs.

Lady Deathstrike: Once per fight, while Ferocity is active, it does not unpause when Blocking an attack.

Psylocke: When consuming a Psi-Charge, 50% chance for it to be refunded.
Unique Synergy: Does not stack with duplicate synergies.
Nico Minoru
Magik
Scarlet Witch (Classic)
Scarlet Witch (Sigil)
Sisters of the Abbey
Nico Minoru: New Pre-Fight spell: Ritual – Nico consumes 30% of her current Health at the start of the fight and stores it as Adrenaline.
Other Synergy Champions: Gain a 30% Stimulate Passive while Blocking.
Unique Synergy: Does not stack with duplicate synergies.
Domino
Deadpool
SIX PACK
Domino: +10% damage against Champions that aren’t female or robots.

Deadpool: Special 1 has a 50% chance to Stun Champions that aren’t female or robots for 2 second(s).
Unique Synergy: Does not stack with duplicate synergies.
Black Panther (Civil War)
Black Panther
Hawkeye
SKILL DOMINATION
Skill Champions deal +[15, 20, 25]% Bleed Damage
Captain America (Infinity War)
Black Widow
Hawkeye
Thor (Ragnarok)
SKILL TRAINING
Skill Champions gain +250 Critical Rating on Basic Attacks.
Unique Synergy: Does not stack with duplicate synergies.
War Machine
Black Widow (Deadly Origin)
Falcon
Night Thrasher
Winter Soldier
SKIRMISH ENHANCEMENT
War Machine: Rupture Debuffs gain +25% Potency.

Black Widow (Deadly Origin): Shock and Incinerate Debuffs gain +15% Potency.

Falcon: Shock and Incinerate Debuffs gain +15% Potency.

Night Thrasher: Shock and Incinerate Debuffs gain +15% Potency.

Winter Soldier: Shock and Incinerate Debuffs gain +15% Potency.
Unique Synergy: Does not stack with duplicate synergies.
Mojo
Psylocke
SMILE FOR THE CAMERAS
Mojo: When the Opponent completes a Prompt, Mojo steals 10% of their current Power.

Psylocke: Psylocke’s personal Power Lock Debuffs last 3 second(s) longer.
Unique Synergy: Does not stack with duplicate synergies.
QuickSilver
Black Bolt
SON OF M
QuickSilver: Increase the duration of non-Damaging Debuffs by 20%.

Black Bolt: Personal Stun Debuff duration increases by 25% and Attacks are guaranteed Critical hits against Stunned Opponents.
Unique Synergy: Does not stack with duplicate synergies.
Hulkling
Captain Marvel
SON OF MAR-VELL
Hulkling: Max Shapeshift Charges is increased to 12.

Captain Marvel: If Captain Marvel would start the fight with less than 10 Energy Charges, start with 10 instead.
Unique Synergy: Does not stack with duplicate synergies.
Doctor Doom
Doctor Strange
Symbiote Supreme
SORCERY REVERSAL
Doctor Doom: Activating the Aura of Haazareth has a 50% chance to Purify all Degeneration, Poison, Incinerate, Bleed and Coldsnap Debuffs.
Solo: Only affects this Champion and does not stack.
The Destroyer
The Overseer
Maestro
Soul Possession
The Destroyer: The first hit of a Special Attack Destroys one Unstoppable and Unblockable Buff on the Opponent, replacing them with Rubble Buffs that last 10 seconds.

The Overseer: Personal Taunt Cooldown is reduced by 10 seconds.

Maestro: Gain 25% Cosmic Radiation potency.
Unique Synergy: Does not stack with duplicate synergies.