Synergy Members: Shock and Coldsnap effects gain +20% potency and are paused during the Opponent’s Special Attacks.
Unique Synergy: Does not stack with duplicate synergies.

+5% Attack rating during the fight and Magneto’s Atonement Synergy gains +25% Potency.

Horsemen gain +30% Prowess Potency.

All of Professor X's Prowess Buffs gain 20% Duration.

Unique Synergy: Does not stack with duplicate Synergies.

Nuclear Core Starting Charge and Overheat Point are increased by +10.

Villain Champions: +5% Health Rating.
Unique Synergy: Does not stack with duplicate Synergies.

All Champions except Nick: If Nick is alive, once per fight when a teammate is inflicted with a Bleed, Poison or Shock Debuff he will drop a Restoration Kit, Purifying the Debuff and Regenerating 10% of their max health over 3 seconds.
Unique Synergy: Does not stack with duplicate synergies.

Special Attack 1 grants an additional 10 Eldritch Energy.

Special Attack 3 Readys all Unreadied Wushu Strikes and triggers Guaranteed Crits for 8 second(s).

Unique Synergy: Does not stack with duplicate synergies.

Up to +25% Armor Rating based on missing Health.

Robots: If a Robot is defeated. They gain a Self-Repair Cross-Fight which gets consumed when they enter their next Fight, Regenerating 25% of their missing health over 20 seconds. This effect ends early if Stunned.
Unique Synergy: Does not stack with duplicate Synergies.

Reduce the potency of incoming Bleed Debuffs by 10%. Reduce the potency by an additional 10% if either Ronin or Hawkeye is Dead.

Increase the duration of Bleed and Disorient Debuffs by 10%. Gain an additional 30% Duration if Black Widow (Deadly Origin) is Dead.

Increase the duration of Bleed and Disorient Debuffs by 10%. Gain an additional 30% Duration if Black Widow (Deadly Origin) is Dead.

Unique Synergy: Does not stack with duplicate synergies.

Defeating #Villain Champions grants 1 Persistent Charge. +10% Attack while fighting #Villains.

Opponent’s Nullify & Stagger effects suffer -65% Ability Accuracy.

Gain Force Field charges 3.5 seconds faster.

Unique Synergy: Does not stack with duplicate Synergies.

Each time Black Widow strikes with Widow’s Insight active she gains 2% of a Bar of Power.

Each time he Exploits a Weakness, Taskmaster has a 30% chance to Inflict a Sabotage Debuff, reducing Defensive Ability Accuracy by 20% for 10 seconds and dealing 10% of Attack as direct Damage when Abilities fail to trigger.

Unique Synergy: Does not stack with duplicate synergies.

Synergy Members: For every 5 personal Shock effects removed by personal abilities, inflict an identical Shock effect.
Unique Synergy: Does not stack with duplicate synergies.

Other Synergy Members: The last hit of Special Attack 1 Incinerates the Opponent for 6 second(s).
This also inflicts Heal Block if all other Champions in this Synergy are present.
Unique Synergy: Does not stack with duplicate synergies.

When becoming Enraged, inflict the Opponent with a 5 seconds Suppression Debuff reducing their Combat Power Rate by 30%.

Solo: Only affects this Champion and does not stack.

Gaining Bloodthirst grants +1 additional Bloodthirst per captured Class Soul.

Gain an Unblockable Buff during Special Attack 1 and 2 while at 150 or more Spirits of the Dead.

Unique Synergy: Does not stack with duplicate synergies.

Synergy Members: Start each fight with an indefinite Failsafe Charge. When struck by a Special Attack 1 or 2, consume the Failsafe to gain an Indestructible Passive for the duration of the Special.
Unique Synergy: Does not stack with duplicate synergies.

Champions have a 100% chance to instantly regain 20% of their HP just before they're knocked out. Each living teammate reduces this chance by 20%.

Synergy Members: Gain a Precision Buff during Special Attacks for each Damage over Time Debuff and Stagger Passive on the Opponent, each increasing Critical Rating by +375.
Unique Synergy: Does not stack with duplicate synergies.

The Control Box is unable to cycle out of Hate mode and Opponents are 20% more likely to use a Heavy Attack. Personal Shock Debuff potency is increased by +60%. Personal Fury Buffs refresh when the Fourth Light Attack lands a hit or it strikes into a block.

Each stack of Hatred increases Regeneration Rate by 1%.

Unique Synergy: Does not stack with duplicate synergies.

+1000 Physical Resistance while Unstoppable.

Basic Attacks against Loki have a 10% chance to miss, while his Opponent is under the effect of any Buff.

Unique Synergy: Does not stack with duplicate synergies.

Synergy Members: Special Attacks don't generate Power for the Opponent if Titania is alive, and gain +10% Attack Rating if Captain Marvel is alive, +750 Critical Rating if Storm is alive, and +400 Critical Damage Rating if Yondu is alive.
Unique Synergy: Does not stack with duplicate synergies.

The first time your Opponent reaches Max Power each fight, drain 5% of their Power and trigger a Power Lock Debuff lasting 2 seconds.

Heavy Attacks have a 100% chance to grant a Fury Buff increasing Attack Rating by 25% for 10 seconds.

Unique Synergy: Does not stack with duplicate synergies.