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Jessica Jones
Daredevil (Classic)
Daredevil (Hell's Kitchen)
EXTRAJUDICIAL PROCEEDINGS
Jessica Jones: Increased chance of throwing the Pizza with Special Attack 1. Also, Dodging attacks using Dexterity inflicts a non-stacking Exhaustion Debuff, lowering Critical Damage Rating by 500 for 6 seconds, instead of granting Precision.

Daredevil (Classic): Whenever the Combo Meter rises past a multiple of 10, gain a True Accuracy Passive for 8 seconds. When fighting Science Champions, gain a True Strike Passive instead.

Daredevil (Hell's Kitchen): Whenever the Combo Meter rises past a multiple of 10, gain a True Accuracy Passive for 8 seconds. When fighting Science Champions, gain a True Strike Passive instead.
Unique Synergy: Does not stack with duplicate synergies.
Nick Fury
Civil Warrior
Iron Man
Iron Man (Infinity War)
Punisher 2099
EXTREME CONDITIONS KIT
All Champions except Nick: If Nick is alive, once per fight when a teammate is inflicted with any Coldsnap, Frost Bite or Incinerate effect he will drop an Extreme Conditions Kit, granting Debuff Immunity for 10 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Hulk (Immortal)
Hulkbuster
Thor
Captain America
Black Panther
EXTREME MEASURES
Hulk (Immortal): Personal Stun Effects have +10% increased duration.

Hulkbuster: Opponents suffer -10% Ability Accuracy while Stunned.

Thor: Opponents suffer -10% Ability Accuracy while Stunned.

Captain America: Opponents suffer -10% Ability Accuracy while Stunned.

Black Panther: Opponents suffer -10% Ability Accuracy while Stunned.
Unique Synergy: Does not stack with duplicate synergies.
Bullseye
Hawkeye
Kate Bishop
Eye for an Eye
Synergy Champions: Dialed In Passives increase the duration of their associated effects by an additional +3%.
Unique Synergy: Does not stack with duplicate synergies.
Shang Chi
Ant-Man
Beast
Black Widow
Captain America
EYES OF THE DRAGON
Shang Chi: Landing a Critical Hit grants an additional +2% Critical Damage Rating. Max 100 hits.

Ant-Man: Landing a Critical Hit grants an additional +2% Critical Damage Rating. Max 100 hits.

Beast: Landing a Critical Hit grants an additional +2% Critical Damage Rating. Max 100 hits.

Black Widow: Landing a Critical Hit grants an additional +2% Critical Damage Rating. Max 100 hits.

Captain America: Landing a Critical Hit grants an additional +2% Critical Damage Rating. Max 100 hits.
Unique Synergy: Does not stack with duplicate synergies.
Abomination (Immortal)
Man-Thing
Venom The Duck
FAIREST OF THEM ALL
Abomination (Immortal): Heavy Attacks inflict an Armor Break Debuff reducing the Opponent’s Armor Rating by [250, 350] for 15 seconds.

Man-Thing: The Opponent’s Combat Power Rate is reduced by up to 50% based on Agitation when struck by a Special Attack.

Venom The Duck: Symbiote Buffs gain +15% duration.
Unique Synergy: Does not stack with duplicate synergies.
Captain America (Infinity War)
Human Torch
Killmonger
FAMILIAR FACES
Captain America (Infinity War): Increase the duration of Bleed Debuffs on the Opponent by 1 second(s).

Human Torch: If the last hit of Special Attack 2 strikes a Block, Human Torch will avoid incoming attacks for 0.85 seconds, causing them to Miss.

Killmonger: Critical Hits are improved to have a 100% chance to cause Bleed.
Unique Synergy: Does not stack with duplicate synergies.
Captain America
Iron Man (Infinity War)
Captain America (Infinity War)
Captain America (WWII)
FAMILIAR INSIGHT
Captain America: Weakness, Fatigue, Bleed, and Petrify Debuffs last 15% longer.

Iron Man (Infinity War): Blocking reduces 10% more damage.
Unique Synergy: Does not stack with duplicate synergies.
Red Goblin
Venom
FAMILY FEUD
Red Goblin: Lose 1 less Bloodlust when defeated.

Venom: Reduce the duration of Venom's Klyntar Buff by 30%.
Unique Synergy: Does not stack with duplicate Synergies.
Black Widow (Deadly Origin)
Red Guardian
FAMILY REUNION
Black Widow (Deadly Origin): Black Widow starts the fight with her Passive Evade active until triggered.

Red Guardian: While charging a Heavy Attack, become Passively Unstoppable for 0.6 seconds. Cooldown: 10 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Stryfe
Cable
Cyclops (Blue Team)
Cyclops (New Xavier School)
Phoenix
FAMILY?
All Champions gain +[4, 5, 6]% Health.
Captain Marvel
Ms. Marvel (Kamala Khan)
FAN CLUB
Captain Marvel: Fury Buffs in Binary Ignition have 10% increased potency.

Ms. Marvel (Kamala Khan): All melee attacks have 20% chance to Armor Break for each stack of active Fury reducing Armor Rating by +15%.
Unique Synergy: Does not stack with duplicate synergies.
Diablo
Annihilus
Doctor Doom
Terrax
Mole Man
FANTASTIC FIENDS
Diablo: 20% chance to Purify a Debuff.

Annihilus: 20% chance to Purify a Debuff.

Doctor Doom: 20% chance to Purify a Debuff.

Terrax: 20% chance to Purify a Debuff.

Mole Man: While Frenzied, Mole Man’s attacks lower Defensive Ability Accuracy by 50% fighting against the #Fantastic Four.
Unique Synergy: Does not stack with duplicate synergies.
Doctor Doom
Annihilus
Diablo
FANTASTIC RAGE
Doctor Doom: Heavy Attacks are guaranteed critical hits while the Opponent is suffering from a Stagger effect.
Solo: Only affects this Champion and does not stack.
Colossus
Galan
Thanos
FARM TO TABLE
Colossus: Colossus’ Special Attack 1 becomes passively Unblockable when activated with 5 or more Personal Armor Up Buffs.

Galan: Converting Resistances into Planetary Mass creates an additional 5 Planetary Mass per Resistance.

Thanos: The first time Thanos would be knocked out in each fight, he gains an Indestructible Buff, keeping the Mad Titan alive for 8 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Colossus
Wolverine
Old Man Logan
FASTBALL SPECIAL
Colossus: Gain a Fastball Fury Buff at the start of the fight, granting +50% Attack and +50% Special Attack rating for 15 seconds.

Wolverine: Begin the fight with 1 Bar of Power.

Old Man Logan: Begin the fight with 1 Bar of Power.
Unique Synergy: Does not stack with duplicate synergies.
Doctor Strange
Ikaris
Iron Man
FATEFUL FRIENDS
Doctor Strange: Upon the Weakness Debuff expiring, gain a Protection Buff for 10 seconds preventing Dr. Strange from taking more than 5% of max health from a single hit.

Ikaris: When Incinerate Debuffs expire naturally or get purified, apply 30% of the amount back to the opponent with full durations.

Iron Man: Inflict an Incinerate Debuff on the Opponent dealing 100% Attack Rating as Energy Damage per second on all Special Attacks.
Unique Synergy: Does not stack with duplicate synergies.
Attuma
Hulk
Juggernaut
Thing
Titania
Absorbing Man
FEAR ITSELF
Attuma: Gain +20% Attack Rating when fighting at Class Advantage, and regain the Attack Rating penalty when fighting at Disadvantage.

Hulk: Gain +20% Attack Rating when fighting at Class Advantage, and regain the Attack Rating penalty when fighting at Disadvantage.

Juggernaut: Gain +20% Attack Rating when fighting at Class Advantage, and regain the Attack Rating penalty when fighting at Disadvantage.

Thing: Gain +20% Attack Rating when fighting at Class Advantage, and regain the Attack Rating penalty when fighting at Disadvantage.

Titania: Gain +20% Attack Rating when fighting at Class Advantage, and regain the Attack Rating penalty when fighting at Disadvantage.

Absorbing Man: Gain +20% Attack Rating when fighting at Class Advantage, and regain the Attack Rating penalty when fighting at Disadvantage.
Unique Synergy: Does not stack with duplicate synergies.
Killmonger
Void
FEARLESS
Killmonger: If Vibranium Armor is active, Killmonger has a 35% chance to Purify a Debuff after a 0.5 second delay and then instantly Regenerate 4% Health per Debuff.

Void: Regenerates 1% Health when inflicting his Intimidating Debuffs.
Unique Synergy: Does not stack with duplicate Synergies.
Howard The Duck
Man-Thing
She-Hulk
FEARSOME FOUR
Howard The Duck: Special 2 gains +25% Ability Accuracy.

Man-Thing: If Struck by a Basic Attack while under the effect of an Unstoppable Buff 100% chance to gain an Indestructible Buff lasting 0.5 second(s).

She-Hulk: Striking a Stunned Opponent with a Heavy Attack grants a Fury Buff increasing Attack by 100% of her Base Attack for 1 second(s).
Unique Synergy: Does not stack with duplicate synergies.