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Hulk (Ragnarok)
Korg
GRANDMASTER’S CHAMPIONS
Hulk (Ragnarok): Crowd Excitement is locked at 100 for an additional 3 seconds.

Korg: When Korg spends 13 or more Crowd Excitement charges through his Heavy Attack, the Armor Break lasts 20 seconds instead. Max Stack: 1.
Unique Synergy: Does not stack with duplicate Synergies.
Toad
Man-Thing
King Groot
GREASY SWAMP BOYS
Toad: +8% Poison Debuff Potency.

Man-Thing: Start the fight with an indefinite Prowess Buff increasing Special Attack Damage by 60%. This Buff is removed after a Special Attack ends.

King Groot: Start the fight with an indefinite Prowess Buff increasing Special Attack Damage by 60%. This Buff is removed after a Special Attack ends.
Unique Synergy: Does not stack with duplicate synergies.
Gladiator
Hyperion
Sentry
Ikaris
Great Guys
Synergy Champions: While far from the Opponent, gain an indefinite Unstoppable Buff. This Buff will not trigger while being struck by the Opponent, and is removed if either Champion re-enters striking distance.
Unique Synergy: Does not stack with duplicate synergies.
Hulk
Void
GRIPPED BY FEAR
Hulk: Gains 1 bar of Power when below 20% Health.

Void: When charging Heavy Attacks, Void can gain up to 3 Fury Buffs, each enhancing his Attack Rating by 20% for 8 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Cassie Lang
Apocalypse
Groot
Hulk (Immortal)
Mephisto
Ms. Marvel (Kamala Khan)
GROW BIG OR GO HOME
Synergy Champions: Gain +6% Block Proficiency and Block Penetration for each Synergy Champion present.
Storm (Pyramid X)
Apocalypse
GUARDIAN OF THE PYRAMID
Storm (Pyramid X): After charging her Dormant Prowess Storm has a 70% chance to trigger a Passive Prowess for each Prowess Buff that is already active. Each increasing Special Damage by 15% for 6 seconds.
If this champion is a Horseman of Apocalypse Gain +30% Critical Rating and +20% Prowess Potency.
Unique Synergy: Does not stack with duplicate synergies.
Heimdall
GUARDIAN OF THE RAINBOW BRIDGE
All Champions except Heimdall: Once per fight Heimdall will intercede on your behalf, the first time when you would be knocked out gain both an Indestructible and an Unstoppable Buff which last for 2 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Black Widow (Claire Voyant)
GUILTY SOULS
All Champions gain +10% Attack when fighting against Villain Opponents.
Unique Synergy: Does not stack with duplicate synergies.
Spider-Gwen
Carnage
Venom
Symbiote Supreme
Venom The Duck
GWENOM RISING
Gwen’s Spider-Sense charges are evolved, reducing their evade chance by half. They also now grant an additional +10% Attack rating each and their max cap is raised by 1.
Solo: Only affects this Champion and does not stack.
Super-Skrull
Mister Fantastic
Human Torch
Invisible Woman
Thing
H.E.R.B.I.E.
Other Synergy Members: If at or below 20% health at the start of the fight, heal 10% of Max Health over 6 second(s). Otherwise gain 60% of a Bar of Power over 6 second(s) instead.
Unique Synergy: Does not stack with duplicate synergies.
Emma Frost
Storm (Pyramid X)
Storm
Professor X
HABITAT
Emma Frost: Gain up to +30% increased Critical Rating scaling with Emma’s Power Meter.

Storm (Pyramid X): +20% Shock Potency.

Storm: +20% Shock Potency.
All Mutants and X-Men except Professor X: +15% Prowess Effect Duration for each Cerebro Charge. Max 60%.
Unique Synergy: Does not stack with duplicate synergies.
Punisher 2099
Red Skull
HAIL HYDRA!
Punisher 2099: Duration of Heal Block, Armor Break, and Power Lock Debuffs are increased by 50%.

Red Skull: Intercepts Heal Block the opponent for 7.5 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Sersi
Spider-Ham
HAM'S ODYSSEY
Sersi: 60% chance to gain an Unstoppable Buff for 6 seconds when a Glancing Buff expires.

Spider-Ham: While Unblockable, activating a Special Attack places 2 additional Porker Poppers if the Opponent is Taunted.
Unique Synergy: Does not stack with duplicate synergies.
The Serpent
Thor
Thor (Jane Foster)
Cull Obsidian
Iron Man (Infinity War)
Hammer Time
Synergy Champions: Hammer attacks gain +20% Attack Rating.
Unique Synergy: Does not stack with duplicate synergies.
Rogue
Absorbing Man
HANDS-ON APPROACH
Rogue: The timer for Rogue's Replicated Buffs is paused during the Opponent's Special Attacks.

Absorbing Man: Reduce the duration of Non-Damaging Debuffs other than Stuns by 50%.
Unique Synergy: Does not stack with duplicate synergies.
Ant-Man
Wasp
Ghost
HARD TO HIT
Ant-Man: When causing a hit to Glance, gains Fury Passive increasing Attack by 25% for 12 seconds. Max: 3. +25% Attack at the start of the fight if Wasp, Ant-Man and Ghost are together in a team.

Wasp: Counter Sting is never disabled when Wasp is below 20% Health. +25% Attack at the start of the fight if Wasp, Ant-Man and Ghost are together in a team.

Ghost: +25% Attack at the start of the fight if Wasp, Ant-Man and Ghost are together in a team.
Unique Synergy: Does not stack with duplicate Synergies.
Ikaris
Juggernaut
Unstoppable Colossus
HARD-HEADED
Ikaris: Gains 10% bonus duration on Incinerate Debuffs when paired with Unstoppable Colossus or Juggernaut (stacks if with both).

Juggernaut: While Unstoppable, gain +100% Combat Power Rate on Heavy Attacks.

Unstoppable Colossus: When gaining Unstoppable Buff will also trigger a 50% Fury Buff for 15 seconds.
Unique Synergy: Does not stack with duplicate synergies.
Sentinel
Squirrel Girl
HARDWIRED FOR HEARTBREAK
Sentinel: Each time an Opponent is immune to one of Sentinel’s personal Incinerate or Shock effects, Sentinel gains 2 Analysis Charges. If Sentinel has his Analysis Complete, he deals a burst of 25% of his Attack Rating as Energy Damage each time instead.

Squirrel Girl: Each time a Robot Opponent is immune to one of Squirrel Girl’s personal Bleed effects, Squirrel Girl converts her Bleed into a Shock effect.
Unique Synergy: Does not stack with duplicate synergies.
Enchantress
Hela
Loki
Hate the Mighty Thunder God
Enchantress: New Enchantment Spell: Flesh to Stone: →,←,←. Inflicts a Petrify Debuff. No effect against #Robots.

Hela: Summoned Sword attacks grant an additional 5 Spirits of the Dead.

Loki: The first hit of Loki’s Heavy Attack prevents him from using his Special Attacks 2 and 3 until the Heavy Attack finishes.
Unique Synergy: Does not stack with duplicate synergies.
Red Goblin
Spider-Man (Symbiote)
HATRED
Red Goblin: While Frenzy is active, Increase Buff Duration by 30%.

Spider-Man (Symbiote): Special 2 creates a non-stacking Fury Buff granting 5% attack for each Armor Break on the Opponent, lasting 20 seconds. While Active, Heavy Attacks inflict 1 additional Armor Break.
Unique Synergy: Does not stack with duplicate Synergies.